此页面是自动翻译的,不保证翻译的准确性。请参阅 英文版 对于源文本。

Determining the Age of First Acute Coronary Syndrome

2023年1月30日 更新者:Deniz Demirci、Antalya Training and Research Hospital

Determining the Cardiovascular Risk Factors Affecting the Age of First Acute Coronary Syndromes

The study aimed to evaluate the association between the obesity grade and the age of the first acute coronary syndrome (ACS). The effect of cardiovascular (CV) risk factors and the age of first ACS in patients with severe obesity was also examined. Consecutive patients with diagnosis of first episode of ACS were prospectively enrolled in 2014 to 2024.Cardiovascular risks of patients will be determined according to clinical and laboratory evaluation and patients were categorized by their body mass indices (BMI). Independent variables that effected the age of first ACS were examined by linear regression analysis

研究概览

详细说明

In the first stage, the first ACS diagnosis of the patients will be tried to be clarified. It will be tried to clarify whether the patients have had ACS before, according to their history, ecg echo and coronary angiography findings. Patients with previous ACS or uncertain ACS diagnosis will not be included in the study.

In the second stage, cardiovascular risk burdens of patients for whom the initial ACS diagnosis is clear will be revealed. Smoking, diabetes mellitus (DM), hypertension (HT), psychological stress, socio-economic status, migration history, cholesterol parameters will be determined. The duration and severity of these risk factors will be determined. In the final model, each risk factor will be examined in detail with its sub-tabs and the effect of each risk factor will be examined separately.

Eventually, a model will be developed that allows predicting the first ACS age. The shortcomings of this model and the narrow scope of the definition of the population will be determined and the direction will be determined for the studies that improve these points.

研究类型

观察性的

注册 (预期的)

2000

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习联系方式

学习地点

      • Antalya、火鸡
        • 招聘中
        • Deniz Demirci
        • 接触:
          • Deniz Demirci, MD

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

18年 及以上 (成人、年长者)

接受健康志愿者

不

有资格学习的性别

全部

取样方法

概率样本

研究人群

First acute coronary syndrome patients admitted to the coronary intensive care unit

描述

Inclusion Criteria:

  • Adult patients with the diagnosis of the first acute coronary syndrome

Exclusion Criteria:

  • Previous cardiovascular disease
  • Chronic renal disease,
  • Chronic obstructive pulmonary disease,
  • Malignancy,
  • Regularly use of statins, antiplatelets or anticoagulants,
  • Situations where oral communication cannot be established with the patient
  • Situations when coronary angiography (CAG) could not be performed .
  • Patients with findings that might be related to previous MI on electrocardiography (ECG) or echocardiography and total occlusion other than 'culprit' lesion and no critical stenosis on CAG

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

研究衡量的是什么?

主要结果指标

结果测量
措施说明
大体时间
Determining the effect of cardiovascular risk factors on the mean age of the first acute coronary syndrome
大体时间:10 years
Detection of the effect of gender, smoking, obesity, diabetes, hypertension, psychological stress, socioeconomic status, migration, dyslipidemia on the age of first acute coronary syndrome episode.
10 years

次要结果测量

结果测量
措施说明
大体时间
Determining the effect of obesity on the mean age of the first acute coronary syndrome
大体时间:6 years
Grouping will be made to obesity degree (Normal, overweight, obesity severe obesity). The first ACS average age of these groups will be compared. Risk factors affecting this average age will not be revealed by linear regression model.
6 years
Determining the effect of migration on the mean age of the first acute coronary syndrome.
大体时间:6 years
Do the patients live in the city where they were born. It will be determined whether he migrated from another city. If there is a migration situation, the reasons will be determined. The migration direction will be determined according to the regions. The impact of migration and migration direction on the first ACS age will be determined.
6 years
Model for calculating the acute coronary syndrome age
大体时间:8 years
Develop a model that calculates the estimated age of ACS on the basis of cardiovascular risk factors.
8 years

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

出版物和有用的链接

负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始 (实际的)

2014年1月2日

初级完成 (预期的)

2023年6月1日

研究完成 (预期的)

2024年6月1日

研究注册日期

首次提交

2020年10月1日

首先提交符合 QC 标准的

2020年10月1日

首次发布 (实际的)

2020年10月8日

研究记录更新

最后更新发布 (实际的)

2023年1月31日

上次提交的符合 QC 标准的更新

2023年1月30日

最后验证

2023年1月1日

更多信息

与本研究相关的术语

药物和器械信息、研究文件

研究美国 FDA 监管的药品

不

研究美国 FDA 监管的设备产品

不

此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.

订阅