Symptom Clusters in Hong Kong Chinese Children With Blood Cancer
2022年4月12日 更新者：Dr Eva Ho、The Hong Kong Polytechnic University
Symptom Clusters in Hong Kong Chinese Children With Blood Cancer:: A Longitudinal Study
Pediatric blood cancer is the most common childhood malignancy.
Despite its survival has been substantially improved, children still have to pay a high price for numerous distressing symptoms resulted from chemotherapy.
Previous studies related to symptom experiences mainly focus on individual symptoms, rather than on multiple symptoms.
Understanding these distressing symptoms may help healthcare professionals to develop appropriate and effective interventions with the aims of alleviating symptom severity and thus promoting the child's psychosocial well-being and quality of life.
研究概览
详细说明
A longitudinal study design will be conducted.
A sample of 120 patients age 5-17years, diagnosed with blood cancer but not yet receive any chemotherapy and able to communicate with Cantonese and read Chinese will be recruited in the pediatric oncology ward of Hong Kong Children's Hospital.
研究类型
观察性的
注册 (预期的)
120
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习联系方式
- 姓名：Ka Wai Lam, PhD
- 电话号码：27666420
- 邮箱：kwkatlam@polyu.edu.hk
学习地点
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Hong Kong,China
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Hong Kong、Hong Kong,China、香港、0000
- 招聘中
- Ka Yan Ho
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参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
5年 至 17年 (孩子)
接受健康志愿者
不
有资格学习的性别
全部
取样方法
非概率样本
研究人群
We will recruit pediatric patients with blood cancer in the Hong Kong Children's Hospital
描述
Inclusion Criteria:
- aged 5 - 17 years old
- diagnosed with blood cancer but not yet receive any chemotherapy
- able to communicate with Cantonese and read Chinese
Exclusion Criteria:
- who are scheduled to have concurrent cancer treatment
- with recurrent malignancy
- medical condition, or cognitive and learning problems in their medical records
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
队列和干预
团体/队列 |
干预/治疗 |
|---|---|
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Questionnaire
This study aims to examine the cancer patient's symptom clusters and their changes over chemotherapy among pediatric patients with blood cancer in Hong Kong
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Participants will complete a set of validated questionnaires (TRSC-C and demographic sheet) before chemotherapy.
They also have to complete the same questionnaires (TRSC-C) again within 1 week after the 1st, 2nd, 3rd, 4th , 5th and 6th courses of chemotherapy via telephone interview by our research assistants.
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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The therapy-related symptom checklist for children (TRSC-C)
大体时间：Before chemotherapy
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For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.
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Before chemotherapy
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The therapy-related symptom checklist for children (TRSC-C) at 1-week
大体时间：At 1-week follow-up
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For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.
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At 1-week follow-up
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The therapy-related symptom checklist for children (TRSC-C) at 1-month
大体时间：At 1-month follow-up
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For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.
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At 1-month follow-up
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The therapy-related symptom checklist for children (TRSC-C) at 3-month
大体时间：At 3-month follow-up
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For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.
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At 3-month follow-up
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The therapy-related symptom checklist for children (TRSC-C) at 6-month
大体时间：At 6-month follow-up
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For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.
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At 6-month follow-up
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Demographic sheet
大体时间：At baseline
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collect the background information of our subjects, including their age, gender, educational attainment, parents' marital status and religious belief
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At baseline
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合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
调查人员
- 首席研究员：Ka Yan Ho, phd、The Hong Kong Polytechnic University
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (实际的)
2021年9月1日
初级完成 (预期的)
2024年9月1日
研究完成 (预期的)
2024年9月1日
研究注册日期
首次提交
2021年5月3日
首先提交符合 QC 标准的
2021年5月11日
首次发布 (实际的)
2021年5月17日
研究记录更新
最后更新发布 (实际的)
2022年4月19日
上次提交的符合 QC 标准的更新
2022年4月12日
最后验证
2022年4月1日
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.