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Home-Based Circuit Training in Adults With Obesity (HBCT)

2026年5月26日 更新者：Chulalongkorn University

Effects of Home-Based Circuit Training on Vascular and Metabolic Health in Adults With Obesity: A Randomized Controlled Trial

Obesity is associated with impaired vascular function, metabolic dysfunction, and reduced physical fitness, which increase cardiovascular disease risk. This randomized controlled trial aims to investigate the effects of a 12-week home-based circuit training program using light-to-moderate resistance on vascular health, body composition, metabolic function, resting metabolic rate, substrate oxidation, physical activity, and physical fitness in adults with obesity. Participants will be randomly assigned to either a home-based circuit training group or a control group maintaining usual daily activities. The findings may support the use of home-based exercise as a practical and time-efficient strategy for obesity management and cardiovascular risk reduction.

研究概览

地位

完全的

条件

干预/治疗

详细说明

Obesity is a major public health concern associated with endothelial dysfunction, arterial stiffness, metabolic impairment, and reduced physical fitness. Although exercise training is recommended for obesity management, adherence to supervised exercise programs may be limited by time constraints and accessibility. Home-based circuit training may provide a feasible alternative that combines aerobic and resistance exercise within a time-efficient format.

This randomized controlled trial investigates the effects of a 12-week home-based circuit training intervention on vascular function, body composition, metabolic function, resting metabolic rate, substrate oxidation, physical activity, and physical fitness in adults with obesity.

Participants with obesity (BMI ≥ 27.5 kg/m²) will be randomly assigned to either a circuit training group or a control group. The intervention group will perform home-based circuit training using light-to-moderate resistance three times weekly for 12 weeks, while the control group will maintain usual activities.

Primary vascular outcomes include flow-mediated dilation, carotid intima-media thickness, brachial-ankle pulse wave velocity, and post-occlusive reactive hyperemia. Secondary outcomes include body composition, fasting plasma glucose, resting metabolic rate, substrate oxidation, physical activity, muscular strength, flexibility, and cardiorespiratory fitness.

The study aims to determine whether home-based circuit training can improve vascular and metabolic health and serve as a practical strategy for reducing cardiovascular risk in adults with obesity.

研究类型

介入性

注册 (实际的)

29

阶段

  • 不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。

学习地点

  • 泰国
    • ฺBangkok
      • Bangkok、ฺBangkok、泰国、10330
        • Faculty of Sports Science, Chulalongkorn University

参与标准

研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

  • 成人

接受健康志愿者

不

描述

Inclusion Criteria:

  • Adults with obesity according to the Asia-Pacific criteria (body mass index [BMI] ≥ 27.5 kg/m²).
  • Able to participate in a home-based exercise program.
  • Willing to provide written informed consent.

Exclusion Criteria:

  • History of uncontrolled diabetes (HbA1c ≥ 10% or blood glucose ≥ 200 mg/dL).
  • Uncontrolled hypertension (≥ 140/90 mmHg).
  • Cardiovascular disease.
  • Chronic obstructive pulmonary disease.
  • Orthopedic conditions limiting exercise participation.
  • Participation in regular exercise programs or sports activities within the previous 3 months

学习计划

本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。

研究是如何设计的？

设计细节

  • 主要用途：治疗
  • 分配：随机化
  • 介入模型：并行分配
  • 屏蔽：无（打开标签）

武器和干预

参与者组/臂
干预/治疗
实验性的：Home-Based Circuit Training
Participants in this group will perform a 12-week home-based circuit training program three times per week. Each session includes warm-up, circuit exercise, and cool-down components designed to improve vascular and metabolic health.
行为的：Home-Based Circuit Training

Participants will perform a 12-week home-based circuit training program three times per week. Each session includes warm-up, circuit-based exercises targeting major muscle groups, and cool-down activities. The intervention is designed to improve vascular and metabolic health in adults with obesity.

The training program consisted of two phases: phase 1 (weeks 1-6) and phase 2 (weeks 7-12).

During phase 1, participants performed resistance exercises at an intensity of 65-70% of one-repetition maximum (1RM). Each exercise consisted of 12 repetitions, with a 1-minute rest between exercises. The lifting tempo was maintained at 2:2 (concentric: eccentric). Participants completed 8 exercises per circuit for a total of 3 circuits, with a 2-minute rest between circuits.

During phase 2, the intensity was increased to 70-75% of 1RM, while maintaining 12 repetitions per exercise. The rest interval between exercises was reduced to 30 seconds, with the same lifting tempo (2:2). Participants complete
无干预：Control Group
participants in the control group will maintain their usual daily activities without participating in the exercise intervention during the study period.

研究衡量的是什么？

主要结果指标

结果测量
措施说明
大体时间
Vascular Function
大体时间：Baseline and 12 weeks
Change in flow-mediated dilation from baseline to 12 weeks.
Baseline and 12 weeks

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

赞助

Chulalongkorn University

调查人员

  • 研究主任：Daroonwan Suksom, PhD、Faculty of Sports Science, Chulalongkorn University, Bangkok, Thailand
  • 首席研究员：Tunyakarn Worasettawat, PhD、Faculty of Sports Science, Chulalongkorn University, Bangkok, Thailand
  • 学习椅：Hirofumi Tanaka, PhD、Department of Kinesiology and Health Education, The University of Texas at Austin, USA

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始 (实际的)

2025年6月18日

初级完成 (实际的)

2025年8月31日

研究完成 (实际的)

2025年12月25日

研究注册日期

首次提交

2026年5月26日

首先提交符合 QC 标准的

2026年5月26日

首次发布 (实际的)

2026年6月2日

研究记录更新

最后更新发布 (实际的)

2026年6月2日

上次提交的符合 QC 标准的更新

2026年5月26日

最后验证

2026年5月1日

更多信息

与本研究相关的术语

关键字

其他相关的 MeSH 术语

其他研究编号

  • HBCT-OB-2026
  • Ratchadapisek Postdoctoral (其他赠款/资助编号：Chulalongkorn University)

计划个人参与者数据 (IPD)

计划共享个人参与者数据 (IPD)？

不

IPD 计划说明

Individual participant data (IPD) may be shared upon reasonable request after publication of the study results and approval by the principal investigator.

药物和器械信息、研究文件

研究美国 FDA 监管的药品

不

研究美国 FDA 监管的设备产品

不

此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.

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