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Home-Based Circuit Training in Adults With Obesity (HBCT)

26. maj 2026 opdateret af: Chulalongkorn University

Effects of Home-Based Circuit Training on Vascular and Metabolic Health in Adults With Obesity: A Randomized Controlled Trial

Obesity is associated with impaired vascular function, metabolic dysfunction, and reduced physical fitness, which increase cardiovascular disease risk. This randomized controlled trial aims to investigate the effects of a 12-week home-based circuit training program using light-to-moderate resistance on vascular health, body composition, metabolic function, resting metabolic rate, substrate oxidation, physical activity, and physical fitness in adults with obesity. Participants will be randomly assigned to either a home-based circuit training group or a control group maintaining usual daily activities. The findings may support the use of home-based exercise as a practical and time-efficient strategy for obesity management and cardiovascular risk reduction.

Studieoversigt

Status

Afsluttet

Betingelser

Detaljeret beskrivelse

Obesity is a major public health concern associated with endothelial dysfunction, arterial stiffness, metabolic impairment, and reduced physical fitness. Although exercise training is recommended for obesity management, adherence to supervised exercise programs may be limited by time constraints and accessibility. Home-based circuit training may provide a feasible alternative that combines aerobic and resistance exercise within a time-efficient format.

This randomized controlled trial investigates the effects of a 12-week home-based circuit training intervention on vascular function, body composition, metabolic function, resting metabolic rate, substrate oxidation, physical activity, and physical fitness in adults with obesity.

Participants with obesity (BMI ≥ 27.5 kg/m²) will be randomly assigned to either a circuit training group or a control group. The intervention group will perform home-based circuit training using light-to-moderate resistance three times weekly for 12 weeks, while the control group will maintain usual activities.

Primary vascular outcomes include flow-mediated dilation, carotid intima-media thickness, brachial-ankle pulse wave velocity, and post-occlusive reactive hyperemia. Secondary outcomes include body composition, fasting plasma glucose, resting metabolic rate, substrate oxidation, physical activity, muscular strength, flexibility, and cardiorespiratory fitness.

The study aims to determine whether home-based circuit training can improve vascular and metabolic health and serve as a practical strategy for reducing cardiovascular risk in adults with obesity.

Undersøgelsestype

Interventionel

Tilmelding (Faktiske)

29

Fase

  • Ikke anvendelig

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

    • ฺBangkok
      • Bangkok, ฺBangkok, Thailand, 10330
        • Faculty of Sports Science, Chulalongkorn University

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

  • Voksen

Tager imod sunde frivillige

Ingen

Beskrivelse

Inclusion Criteria:

  • Adults with obesity according to the Asia-Pacific criteria (body mass index [BMI] ≥ 27.5 kg/m²).
  • Able to participate in a home-based exercise program.
  • Willing to provide written informed consent.

Exclusion Criteria:

  • History of uncontrolled diabetes (HbA1c ≥ 10% or blood glucose ≥ 200 mg/dL).
  • Uncontrolled hypertension (≥ 140/90 mmHg).
  • Cardiovascular disease.
  • Chronic obstructive pulmonary disease.
  • Orthopedic conditions limiting exercise participation.
  • Participation in regular exercise programs or sports activities within the previous 3 months

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

  • Primært formål: Behandling
  • Tildeling: Randomiseret
  • Interventionel model: Parallel tildeling
  • Maskning: Ingen (Åben etiket)

Våben og indgreb

Deltagergruppe / Arm
Intervention / Behandling
Eksperimentel: Home-Based Circuit Training
Participants in this group will perform a 12-week home-based circuit training program three times per week. Each session includes warm-up, circuit exercise, and cool-down components designed to improve vascular and metabolic health.

Participants will perform a 12-week home-based circuit training program three times per week. Each session includes warm-up, circuit-based exercises targeting major muscle groups, and cool-down activities. The intervention is designed to improve vascular and metabolic health in adults with obesity.

The training program consisted of two phases: phase 1 (weeks 1-6) and phase 2 (weeks 7-12).

During phase 1, participants performed resistance exercises at an intensity of 65-70% of one-repetition maximum (1RM). Each exercise consisted of 12 repetitions, with a 1-minute rest between exercises. The lifting tempo was maintained at 2:2 (concentric: eccentric). Participants completed 8 exercises per circuit for a total of 3 circuits, with a 2-minute rest between circuits.

During phase 2, the intensity was increased to 70-75% of 1RM, while maintaining 12 repetitions per exercise. The rest interval between exercises was reduced to 30 seconds, with the same lifting tempo (2:2). Participants complete

Ingen indgriben: Control Group
participants in the control group will maintain their usual daily activities without participating in the exercise intervention during the study period.

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Vascular Function
Tidsramme: Baseline and 12 weeks
Change in flow-mediated dilation from baseline to 12 weeks.
Baseline and 12 weeks

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Efterforskere

  • Studieleder: Daroonwan Suksom, PhD, Faculty of Sports Science, Chulalongkorn University, Bangkok, Thailand
  • Ledende efterforsker: Tunyakarn Worasettawat, PhD, Faculty of Sports Science, Chulalongkorn University, Bangkok, Thailand
  • Studiestol: Hirofumi Tanaka, PhD, Department of Kinesiology and Health Education, The University of Texas at Austin, USA

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Faktiske)

18. juni 2025

Primær færdiggørelse (Faktiske)

31. august 2025

Studieafslutning (Faktiske)

25. december 2025

Datoer for studieregistrering

Først indsendt

26. maj 2026

Først indsendt, der opfyldte QC-kriterier

26. maj 2026

Først opslået (Faktiske)

2. juni 2026

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

2. juni 2026

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

26. maj 2026

Sidst verificeret

1. maj 2026

Mere information

Begreber relateret til denne undersøgelse

Andre undersøgelses-id-numre

  • HBCT-OB-2026
  • Ratchadapisek Postdoctoral (Andet bevillings-/finansieringsnummer: Chulalongkorn University)

Plan for individuelle deltagerdata (IPD)

Planlægger du at dele individuelle deltagerdata (IPD)?

INGEN

IPD-planbeskrivelse

Individual participant data (IPD) may be shared upon reasonable request after publication of the study results and approval by the principal investigator.

Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter

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Ingen

Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .

Kliniske forsøg med Home-Based Circuit Training

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