Effect of Coordinative Locomotor Training in Children With Cerebral Palsy (CLT-PHYSIO-CP)
2026年7月21日 更新者:Muhammad Muneeb Jafar、University of Faisalabad
Effect of Coordinative Locomotor Training as Compared to Conventional Physio Therapy in Improving Interlimb Coordination and Dynamic Balance Among Children With Spastic Hemiplegic Cerebral Palsy
Cerebral palsy is a brain disorder that affects how children move their bodies.
Children with spastic hemiplegic CP have stiffness on one side of the body, making it hard to walk and balance.
This study will test a special exercise program called Coordinative Locomotor Training (CLT).
CLT uses running and skating movements to train both arms and legs to work together.
The investigator want to see if CLT works better than regular physiotherapy for improving coordination and balance in participants.
Half of the children will do CLT, and the other half will do regular exercises.
The investogar will measure their balance and walking ability before and after 4 weeks of training.
研究概览
地位
主动,不招人
条件
详细说明
This is a double-blinded, parallel-group, randomized controlled trial conducted at the Department of Rehabilitation Sciences, The University of Faisalabad.
A total of 38 children diagnosed with spastic hemiplegic cerebral palsy (GMFCS Level I-II), aged 8 to 12 years, will be recruited from pediatric physiotherapy centers.
Participants will be randomly assigned (1:1 ratio) using a computer-generated randomization list to either the Experimental Group (CLT) or the Control Group (CPT).
The Experimental Group (n=19) will receive Coordinative Locomotor Training based on Proprioceptive Neuromuscular Facilitation (PNF) sprinter and skater patterns.
The intervention will be delivered in three postures (supine, sitting, and single-leg stand) for 3 sets of 5 repetitions with a 10-second hold and 10-second rest, lasting 30 minutes per session, 3 times per week for 4 weeks (total 12 sessions).
The Control Group (n=19) will receive conventional physiotherapy consisting of hot pack application for 10 minutes, rotational exercises for 5 minutes, followed by stretching and resistance training for 15 minutes, lasting 30 minutes per session, 3 times per week for 4 weeks (total 12 sessions).
The primary outcome measures are interlimb coordination (assessed via 1-step time asymmetry and stride time variability) and dynamic balance (Pediatric Balance Scale).
Secondary outcomes include functional gait (TUG and 10MWT) and static balance (one-leg stand test).Participants will not know whether they are in experiment or control group.
A blinded assessor will evaluate all participants at baseline (Week 0) and post-intervention (Week 8).
Data will be analyzed using SPSS version 23.
研究类型
介入性
注册 (实际的)
38
阶段
- 不适用
联系人和位置
本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。
学习地点
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Punjab Province
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Faisalābad、Punjab Province、巴基斯坦、3800
- The University of Faisalabad
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参与标准
研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
- 孩子
接受健康志愿者
不
描述
Inclusion Criteria:
- Children aged 8 to 12 years.
- Diagnosed with spastic hemiplegic cerebral palsy.
- GMFCS Level I or II.
- Ability to follow simple verbal instructions.
- Medically stable with no changes in anti-spastic medication in the last 3 months.
Exclusion Criteria:
- Orthopedic surgery or Botulinum toxin injection in the last 6 months.
- Severe cognitive impairment preventing cooperation.
- Visual or vestibular deficits affecting balance.
- Uncontrolled seizures.
- Other neurological or musculoskeletal disorders unrelated to CP.
学习计划
本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。
研究是如何设计的?
设计细节
- 主要用途:治疗
- 分配:随机化
- 介入模型:并行分配
- 屏蔽:双倍的
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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实验性的:Coordinative Locomotor Training (CLT)
PNF-based sprinter and skater patterns in supine, sitting, and standing.
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Participants perform PNF sprinter pattern (flexion/adduction/external rotation on one side with extension/abduction/internal rotation on the opposite side) and skater pattern (reciprocal upper and lower limb movements).
Exercises are done for 3 sets of 5 reps, 10-sec holds, 30 min/session, 3x/week for 4 weeks.
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有源比较器:Conventional Physiotherapy (CPT)
ROM exercises, stretching, and resistance training.
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rotational exercises (5 min), then passive stretching of hamstrings, quadriceps, and ankle plantarflexors combined with resistance training using elastic bands (15 min).
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研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Change in Interlimb Coordination
大体时间:Baseline (Week 0) and Post-intervention (Week 8)
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Measured by 1-step time asymmetry (NAI) during gait analysis.
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Baseline (Week 0) and Post-intervention (Week 8)
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Change in Dynamic Balance
大体时间:Baseline (Week 0) and Post-intervention (Week 8)
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Measured by the Pediatric Balance Scale (PBS).
A 14-item scale scoring from 0 to 56.
Higher scores indicate better balance.
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Baseline (Week 0) and Post-intervention (Week 8)
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Change in Functional Gait Speed
大体时间:Baseline (Week 0) and Post-intervention (Week 8)
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Measured by the Time Up and Go (TUG) test in seconds,
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Baseline (Week 0) and Post-intervention (Week 8)
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合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (实际的)
2026年2月15日
初级完成 (实际的)
2026年6月15日
研究完成 (估计的)
2026年8月10日
研究注册日期
首次提交
2026年6月8日
首先提交符合 QC 标准的
2026年6月14日
首次发布 (实际的)
2026年6月16日
研究记录更新
最后更新发布 (实际的)
2026年7月23日
上次提交的符合 QC 标准的更新
2026年7月21日
最后验证
2026年6月1日
更多信息
与本研究相关的术语
其他研究编号
- TUF/EIRB/ 199 /26
计划个人参与者数据 (IPD)
计划共享个人参与者数据 (IPD)?
不
药物和器械信息、研究文件
研究美国 FDA 监管的药品
不
研究美国 FDA 监管的设备产品
不
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