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Effect of Coordinative Locomotor Training in Children With Cerebral Palsy (CLT-PHYSIO-CP)

14. juni 2026 opdateret af: Muhammad Muneeb Jafar, University of Faisalabad

Effect of Coordinative Locomotor Training as Compared to Conventional Physio Therapy in Improving Interlimb Coordination and Dynamic Balance Among Children With Spastic Hemiplegic Cerebral Palsy

Cerebral palsy is a brain disorder that affects how children move their bodies. Children with spastic hemiplegic CP have stiffness on one side of the body, making it hard to walk and balance. This study will test a special exercise program called Coordinative Locomotor Training (CLT). CLT uses running and skating movements to train both arms and legs to work together. The investigator want to see if CLT works better than regular physiotherapy for improving coordination and balance in participants. Half of the children will do CLT, and the other half will do regular exercises. The investogar will measure their balance and walking ability before and after 4 weeks of training.

Studieoversigt

Status

Aktiv, ikke rekrutterende

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

This is a double-blinded, parallel-group, randomized controlled trial conducted at the Department of Rehabilitation Sciences, The University of Faisalabad. A total of 38 children diagnosed with spastic hemiplegic cerebral palsy (GMFCS Level I-II), aged 8 to 12 years, will be recruited from pediatric physiotherapy centers. Participants will be randomly assigned (1:1 ratio) using a computer-generated randomization list to either the Experimental Group (CLT) or the Control Group (CPT). The Experimental Group (n=19) will receive Coordinative Locomotor Training based on Proprioceptive Neuromuscular Facilitation (PNF) sprinter and skater patterns. The intervention will be delivered in three postures (supine, sitting, and single-leg stand) for 3 sets of 5 repetitions with a 10-second hold and 10-second rest, lasting 30 minutes per session, 3 times per week for 4 weeks (total 12 sessions). The Control Group (n=19) will receive conventional physiotherapy consisting of hot pack application for 10 minutes, rotational exercises for 5 minutes, followed by stretching and resistance training for 15 minutes, lasting 30 minutes per session, 3 times per week for 4 weeks (total 12 sessions). The primary outcome measures are interlimb coordination (assessed via 1-step time asymmetry and stride time variability) and dynamic balance (Pediatric Balance Scale). Secondary outcomes include functional gait (TUG and 10MWT) and static balance (one-leg stand test).Participants will not know whether they are in experiment or control group. A blinded assessor will evaluate all participants at baseline (Week 0) and post-intervention (Week 8). Data will be analyzed using SPSS version 23.

Undersøgelsestype

Interventionel

Tilmelding (Faktiske)

38

Fase

  • Ikke anvendelig

Kontakter og lokationer

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Studiesteder

  • Pakistan
    • Punjab Province
      • Faisalābad, Punjab Province, Pakistan, 3800
        • The University of Faisalabad

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

  • Barn

Tager imod sunde frivillige

Ingen

Beskrivelse

Inclusion Criteria:

  • Children aged 8 to 12 years.
  • Diagnosed with spastic hemiplegic cerebral palsy.
  • GMFCS Level I or II.
  • Ability to follow simple verbal instructions.
  • Medically stable with no changes in anti-spastic medication in the last 3 months.

Exclusion Criteria:

  • Orthopedic surgery or Botulinum toxin injection in the last 6 months.
  • Severe cognitive impairment preventing cooperation.
  • Visual or vestibular deficits affecting balance.
  • Uncontrolled seizures.
  • Other neurological or musculoskeletal disorders unrelated to CP.

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

  • Primært formål: Behandling
  • Tildeling: Randomiseret
  • Interventionel model: Parallel tildeling
  • Maskning: Dobbelt

Våben og indgreb

Deltagergruppe / Arm
Intervention / Behandling
Eksperimentel: Coordinative Locomotor Training (CLT)
PNF-based sprinter and skater patterns in supine, sitting, and standing.
Andet: Coordinative Locomotor Training
Participants perform PNF sprinter pattern (flexion/adduction/external rotation on one side with extension/abduction/internal rotation on the opposite side) and skater pattern (reciprocal upper and lower limb movements). Exercises are done for 3 sets of 5 reps, 10-sec holds, 30 min/session, 3x/week for 4 weeks.
Aktiv komparator: Conventional Physiotherapy (CPT)
ROM exercises, stretching, and resistance training.
Andet: Conventional Physiotherapy
rotational exercises (5 min), then passive stretching of hamstrings, quadriceps, and ankle plantarflexors combined with resistance training using elastic bands (15 min).

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Change in Interlimb Coordination
Tidsramme: Baseline (Week 0) and Post-intervention (Week 8)
Measured by 1-step time asymmetry (NAI) during gait analysis.
Baseline (Week 0) and Post-intervention (Week 8)
Change in Dynamic Balance
Tidsramme: Baseline (Week 0) and Post-intervention (Week 8)
Measured by the Pediatric Balance Scale (PBS). A 14-item scale scoring from 0 to 56. Higher scores indicate better balance.
Baseline (Week 0) and Post-intervention (Week 8)

Sekundære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Change in Functional Gait Speed
Tidsramme: Baseline (Week 0) and Post-intervention (Week 8)
Measured by the Time Up and Go (TUG) test in seconds,
Baseline (Week 0) and Post-intervention (Week 8)

Samarbejdspartnere og efterforskere

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Sponsor

University of Faisalabad

Datoer for undersøgelser

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Studer store datoer

Studiestart (Faktiske)

15. februar 2026

Primær færdiggørelse (Anslået)

15. juni 2026

Studieafslutning (Anslået)

1. juli 2026

Datoer for studieregistrering

Først indsendt

8. juni 2026

Først indsendt, der opfyldte QC-kriterier

14. juni 2026

Først opslået (Faktiske)

16. juni 2026

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

16. juni 2026

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

14. juni 2026

Sidst verificeret

1. juni 2026

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

  • TUF/EIRB/ 199 /26

Plan for individuelle deltagerdata (IPD)

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INGEN

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