Evaluation of the Effects of Orthognathic Surgeries on the Temporomandibular Joint Using a Mandibular Movement Analyzer Device
研究概览
研究类型
注册 (估计的)
联系人和位置
学习联系方式
- 姓名:Lorincz Gergely, medical
- 电话号码:+36306640386
- 邮箱:lorincz.gergely@semmelweis.hu
学习地点
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Budapest、匈牙利、1088
- 招聘中
- Semmelweis University Department of Paediatric Dentistry and Orthodontics
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接触:
- Gergely Lorincz, medical
- 电话号码:+36306640386
- 邮箱:lorincz.gergely@semmelweis.hu
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参与标准
资格标准
适合学习的年龄
- 成人
- 年长者
接受健康志愿者
取样方法
研究人群
描述
Inclusion Criteria:
Age between 18 and 45 years (skeletally mature patients). Severe dentofacial deformity requiring combined orthodontic and orthognathic surgical treatment (e.g., Le Fort I osteotomy, bilateral sagittal split osteotomy, or bimaxillary procedure).
Presurgical orthodontic preparation completed or near completion. Signed written informed consent prior to study enrollment. Ability and willingness to attend all scheduled preoperative and postoperative follow-up visits.
Exclusion Criteria:
History of previous orthognathic or major craniofacial surgical interventions. Congenital craniofacial anomalies, cleft lip and/or palate, or genetic syndromes affecting the musculoskeletal or facial skeleton.
Pre-existing severe degenerative temporomandibular joint disease (e.g., advanced osteoarthritis, idiopathic condylar resorption, or ankylosis).
Systemic rheumatologic, autoimmune, or connective tissue disorders affecting bone and joint metabolism (e.g., rheumatoid arthritis, lupus).
Active neurological or neuromuscular disorders affecting jaw movement or motor control.
Current use of medications significantly altering bone metabolism or neuromuscular function (e.g., chronic systemic corticosteroids, antiresorptive agents).
Severe unmanaged bruxism or acute trauma to the maxillofacial region
学习计划
研究是如何设计的?
设计细节
队列和干预
团体/队列 |
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Orthognathic Surgery Cohort
Adult patients diagnosed with dentofacial deformities undergoing combined orthodontic and orthognathic surgical treatment (e.g., bilateral sagittal split osteotomy, Le Fort I osteotomy, or bimaxillary surgery).
Participants undergo preoperative and postoperative clinical and functional assessments of the temporomandibular joint (TMJ), including mandibular motion, condylar position analysis, and evaluation of temporomandibular signs and symptoms.
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研究衡量的是什么?
主要结果指标
结果测量 |
大体时间 |
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Change in Three-Dimensional Condylar Displacement
大体时间:Baseline (preoperative, within 4 weeks prior to surgery) and at 6 months postoperatively
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Baseline (preoperative, within 4 weeks prior to surgery) and at 6 months postoperatively
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Change in Mandibular Maximum Range of Motion
大体时间:Baseline (preoperative, within 4 weeks prior to surgery) and at 6 months postoperatively
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Baseline (preoperative, within 4 weeks prior to surgery) and at 6 months postoperatively
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合作者和调查者
出版物和有用的链接
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (估计的)
研究完成 (估计的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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