Role of Total Thyroidectomy in Relieving Local Symptoms in Hashimoto's Thyroiditis
The Role of Total Thyroidectomy in Relieving Chronic Local Symptoms Associated With Hashimoto's Thyroiditis: Prospective Cohort Study
This study aims to evaluate the role and effectiveness of total thyroidectomy in relieving compressive and local symptoms (such as dysphagia, dyspnea, and anterior neck pain/discomfort) in patients with Hashimoto's thyroiditis who fail to improve with conservative medical management.
研究概览
详细说明
Hashimoto's thyroiditis is a chronic autoimmune disease often presenting with goiter and local pressure symptoms. While levothyroxine replacement is standard for hypothyroidism, persistent compressive symptoms, cosmetic concerns, or suspicion of malignancy may necessitate surgical intervention.
This study investigates patients diagnosed with Hashimoto's thyroiditis presenting with significant local symptoms. Eligible patients undergoing total thyroidectomy will be evaluated preoperatively and postoperatively to assess symptom resolution, postoperative complication rates (such as hypocalcemia and recurrent laryngeal nerve injury), and overall patient satisfaction following surgery.
研究类型
注册 (估计的)
联系人和位置
学习联系方式
- 姓名：Ahmed Atef Muslim, Bachelor of Medicine and Surge
- 电话号码：+201099626447
- 邮箱：ahmed.atef.465.aa@gmail.com
学习地点
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Asyut Governorate
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Asyut、Asyut Governorate、埃及、71515
- Assiut University Hospitals
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接触：
- Ahmed Atef Muslim, Bachelor of Medicine and Surge
- 电话号码：+201099626447
- 邮箱：ahmed.atef.465.aa@gmail.com
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-
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
Patients diagnosed with Hashimoto's thyroiditis who suffer from persistent local compressive symptoms and undergo total thyroidectomy at the Department of Surgery, Assiut University Hospitals.
描述
Inclusion Criteria:
- Adults patients with confirmed Hashimoto's thyroiditis (elevated serum anti-thyroid peroxidase \anti-thyroglobulin antibodies, characteristic ultrasound findings and/or positive fine needle aspiration cytology)
- Biochemically euthyroid with normal thyroid function test.
- Presence of persistent local symptoms (neck pain, throat discomfort,neck tightness,chocking) for more than 6 months
- Patient fit and motivated to surgery.
Exclusion Criteria:
- Confirmed or high-suspicion thyroid malignancy (Bethesda V or IV on FNAC
- Previous thyroid or neck surgery
- Patient refusal to participate in the study
- Severe comorbidities precluding general anesthesia
- Active psychiatric illness
学习计划
研究是如何设计的？
设计细节
- 观测模型：COHORT
- 时间观点：PROSPECTIVE
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Improvement or Relief of Local Compressive Symptoms
大体时间：6 months postoperatively
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Assessment of changes in patient-reported compressive symptoms (such as dysphagia, dyspnea, and local neck discomfort or pressure) following total thyroidectomy compared to baseline status. |
6 months postoperatively
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Incidence of Postoperative Complications
大体时间：Up to 30 days postoperatively
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Rate of surgical complications including transient or permanent hypocalcemia, recurrent laryngeal nerve injury, and wound complications. |
Up to 30 days postoperatively
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合作者和调查者
调查人员
- 研究主任：Ahmed Gamal Hamdan, Lecturer
研究记录日期
研究主要日期
学习开始 (估计的)
初级完成 (估计的)
研究完成 (估计的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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