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COMPARATIVE ANALYSIS OF DUAL-TASK COGNITIVE-MOTOR TRAINING AND ACTION OBSERVATION THERAPY ON UPPER LIMB FUNCTIONAL RECOVERY AND HAND DEXTERITY IN PATIENTS WITH SUBACUTE STROKE

2026年11月8日 更新者：Ibadat International University, Islamabad

This randomized controlled trial aims to compare the effects of dual-task cognitive-motor training and action observation therapy on upper limb functional recovery and hand dexterity in patients with subacute stroke.

研究概览

地位

招聘中

条件

干预/治疗

研究类型

介入性

注册 (估计的)

48

阶段

  • 不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。

学习联系方式

研究联系人备份

学习地点

参与标准

研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

40年 至 75年 (成人、年长者)

接受健康志愿者

不

有资格学习的性别

全部

描述

Inclusion Criteria:

  • First-ever ischemic or hemorrhagic stroke (confirmed by CT/MRI).
  • Subacute stage of stroke 3-6 months
  • Age 40-75 years, male andfemale..
  • Mini Mental State Examination (MMSE) >24.
  • Manual muscle testing (MMT) > 3.

Exclusion Criteria:

  • Bilateral stroke or brainstem stroke.
  • Severe neglect, apraxia, or global aphasia.
  • Severe visual field defects such as hemianopia.
  • Uncontrolled hypertension, unstable cardiac issues, and uncontrolled diabetes.
  • Neurological disorders (Parkinson's, MS, and Alzheimer's).
  • Fractures or contracture (Modified Ashworth Scale < 2).
  • Pre-existing musculoskeletal Issues in the upper limb

学习计划

本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。

研究是如何设计的？

设计细节

  • 主要用途：治疗
  • 分配：随机化
  • 介入模型：并行分配
  • 屏蔽：单身的

武器和干预

参与者组/臂
干预/治疗
实验性的：Group A (Dual-Task Cognitive-Motor Training)

Dual-Task Cognitive-Motor Training
其他：Dual-Task Cognitive-Motor Training

Week 1: Simple Cognitive + Motor Tasks Motor Tasks

  • Reaching
  • Ball transfer
  • Cone stacking
  • Block moving Cognitive Tasks Performed simultaneously
  • Counting forward
  • Naming colors
  • Saying weekdays
  • Simple word recall Week 2: Moderate Cognitive Loading Motor Tasks
  • up stacking
  • Object sorting
  • Arm elevation tasks Cognitive Tasks
  • Counting backward
  • Simple calculations
  • Memory recall Progression
  • Increase movement repetitions
  • Reduce rest periods Week 3: Functional Dual Tasks

Motor Tasks ADL-based:

  • Folding towel
  • Carrying objects
  • Simulated feeding Cognitive Tasks
  • Responding to questions
  • Word generation
  • Sequencing activities Week 4: Complex Real-Life Dual Tasks

Motor Tasks Complex upper limb activities:

  • Tray carrying
  • Multi-step object transfer
  • Kitchen simulation
  • Dressing simulation Cognitive Tasks
  • Serial subtraction
  • Problem solving
  • Delayed recall
  • Following multistep commands
有源比较器：Group B (Action Observation Therapy)

Action Observation Therapy
其他：Action Observation Therapy

Week 1: Basic Gross Motor Tasks

Observation Tasks Patient watches videos or therapist demonstrations of:

  • shoulder flexion
  • elbow flexion/extension
  • reaching movements
  • grasp and release activities Execution Patient imitates observed movements using affected upper limb. Functional Tasks
  • Reaching cone
  • Picking up cup
  • Moving blocks
  • Table wiping Week 2: Bilateral Functional Activities Observation
  • Bilateral reaching
  • Holding objects
  • Cup transfer
  • Folding towel Execution Patient repeats observed activities. Progression
  • Increase repetitions
  • Add object manipulation
  • Encourage movement accuracy Week 3: Fine Motor and Dexterity Tasks Observation
  • Peg placement
  • Buttoning
  • Spoon use
  • Writing simulation
  • Coin transfer Execution Focused practice after each observation clip. Progression
  • Faster task completion
  • Reduced verbal cueing
  • More affected side involvement Week 4: Complex Functional ADL Tasks Observation
  • Drinking from glass
  • Opening container
  • Dressing-relate

研究衡量的是什么？

主要结果指标

结果测量
措施说明
大体时间
Barthel Index (BI)
大体时间：Baseline, 2nd week, 4th week

It measures independence in daily activities. Test-retest reliability: ICC = 0.89 (High stability)
Baseline, 2nd week, 4th week
Fugl-Meyer Assessment Upper Extremity (FMA-UE)
大体时间：Baseline, 2nd week, 4th week

It is a stroke-specific, performance-based outcome measure used to assess upper limb motor recovery following a stroke. The FMA-UE consists of 33 items evaluating reflex activity, voluntary movement within and out of synergy, wrist and hand function, and coordination/speed. Each item is scored on a 3-point ordinal scale (0 = cannot perform, 1 = performs partially, 2 = performs fully), with a maximum score of 66 indicating optimal motor function.
Baseline, 2nd week, 4th week
Box and Block Test (BBT)
大体时间：Baseline, 2nd week, 4th week

It measures gross manual dexterity / hand function. Concurrent validity: r = 0.801 (Strong correlation)
Baseline, 2nd week, 4th week
Trail Making Test Part B
大体时间：Baseline, 2nd week, 4th week

It measures attention shifting, processing speed, and executive function. ICC = 0.93 Excellent test-retest reliability
Baseline, 2nd week, 4th week

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

赞助

Ibadat International University, Islamabad

调查人员

  • 学习椅：Nazish Rafique、Ibadat International University

出版物和有用的链接

负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。

一般刊物

  • 1. Alvarez-Rodríguez M., López-Dolado, E., Salas-Monedero, M., Lozano-Berrio, V., Ceruelo-Abajo, S., Gil-Agudo, A., & de los Reyes-Guzmán, A. (2020). Concurrent validity of a virtual version of Box and Block Test for patients with neurological disorders. World Journal of Neuroscience, 10(1), 79-89. 2. An H. S., & Kim, D. J. (2021). Effects of activities of daily living-based dual-task training on upper extremity function, cognitive function, and quality of life in stroke patients. Osong Public Health and Research Perspectives, 12(5), 304-313. 3.Borges, L. R. D. M., Fernandes, A. B. G. S., Oliveira dos Passos, J., Rego, I. A. O., & Campos, T. F. (2022). Action observation for upper limb rehabilitation after stroke. Cochrane Database of Systematic Reviews, 2022(8), CD011887. 4. GB 2021 Stroke Risk Factor Collaborators. (2024). Global, regional, and national burden of stroke and its risk factors, 1990-2021: A systematic analysis for the Global Burden of Disease Study 2021. The Lancet Neurology, 23(10), 973-1003. 5.Han, C., Wang, Q., Meng, P. P., & Qi, M. Z. (2013). Effects of intensity of arm training on hemiplegic upper extremity motor recovery in stroke patients: A randomized controlled trial. Clinical Rehabilitation, 27(1), 75-81. 6.Khalid, Z., Gulalai, Qamar, K., Khan, M., Afridi, A., & Rahat, A. (2024). Effects of action observation exercises with complex tasks on upper limb function in acute stroke. Journal of Health and Rehabilitation Research, 4(1), 318-324. 7.Mancuso, M., Di Tondo, S., Costantini, E., Damora, A., Sale, P., & Abbruzzese, L. (2021). Action Observation Therapy for upper limb recovery in patients with stroke: A randomized controlled pilot study. Brain Sciences, 11(3), 290. 8.Milani, G., Baroni, A., Galluccio, M., Fadiga, L., & Rossettini, G. (2025). Action Observation Training for upper limb stroke rehabilitation: A pilot study on the role of attention. Journal of Clinical Medicine, 14(18), 6618. Page, S. J., Hade, E., & Persch, A. (2015). Psycho

有用的网址

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始 (实际的)

2026年7月9日

初级完成 (估计的)

2026年11月18日

研究完成 (估计的)

2026年11月30日

研究注册日期

首次提交

2026年11月8日

首先提交符合 QC 标准的

2026年11月8日

首次发布 (实际的)

2026年11月13日

研究记录更新

最后更新发布 (实际的)

2026年11月13日

上次提交的符合 QC 标准的更新

2026年11月8日

最后验证

2026年11月1日

更多信息

与本研究相关的术语

关键字

其他相关的 MeSH 术语

其他研究编号

  • IIUI/RERC/ADT/2026/07/380

计划个人参与者数据 (IPD)

计划共享个人参与者数据 (IPD)？

不

药物和器械信息、研究文件

研究美国 FDA 监管的药品

不

研究美国 FDA 监管的设备产品

不

此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.

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