In vitro activities of moxifloxacin against 900 aerobic and anaerobic surgical isolates from patients with intra-abdominal and diabetic foot infections

Charles E Edmiston, Candace J Krepel, Gary R Seabrook, Lewis R Somberg, Atilla Nakeeb, Robert A Cambria, Jonathan B Towne, Charles E Edmiston, Candace J Krepel, Gary R Seabrook, Lewis R Somberg, Atilla Nakeeb, Robert A Cambria, Jonathan B Towne

Abstract

The in vitro activities of moxifloxacin, ciprofloxacin, levofloxacin, gatifloxacin, imipenem, piperacillin-tazobactam, clindamycin, and metronidazole against 900 surgical isolates were determined using NCCLS testing methods. Moxifloxacin exhibited good to excellent antimicrobial activity against most aerobic (90.8%) and anaerobic (97.1%) microorganisms, suggesting that it may be effective for the treatment of polymicrobial surgical infections.

Source: PubMed

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