Clinical efficacy of an enhanced recovery after surgery protocol in patients undergoing robotic-assisted laparoscopic prostatectomy

Jie Cao, Jie Gu, Yan Wang, Xianjuan Guo, Xu Gao, Xiaoying Lu, Jie Cao, Jie Gu, Yan Wang, Xianjuan Guo, Xu Gao, Xiaoying Lu

Abstract

Objective: To evaluate the application of an enhanced recovery after surgery (ERAS) protocol in patients undergoing robot-assisted laparoscopic prostatectomy (RALP).

Methods: We conducted a retrospective cohort study of 136 patients who underwent RALP between August 2017 and June 2018 as the control group and a prospective analysis of 106 patients who underwent RALP between January 2019 and January 2020 as the ERAS group. ERAS focused on preoperative education, nutritional intervention, electrolyte solution intake, restrictive fluid infusion, body warming, no indwelling central venous catheter, use of nonsteroidal anti-inflammatory drugs (NSAIDs), early mobilization, and eating recovery.

Results: The times from RALP to the first intake of clear liquid; first ambulation; first defecation; first fluid, semi-liquid, and general diet; drain removal; and length of hospital stay (LOS) were significantly shorter, and operative time, fluid infusion within 24 hours, postoperative day (POD) 1 albumin, POD 1 hemoglobin, and POD 2 drainage were significantly higher in the ERAS group. Five patients (3.8%) in the ERAS group developed postoperative complications (urine leakage, n = 4; intestinal obstruction, n = 1), while 1 patient (0.7%) in the control group developed intestinal obstruction.

Conclusions: ERAS effectively accelerated patient rehabilitation and reduced the LOS for patients undergoing RALP.

Keywords: Prostate cancer; enhanced recovery after surgery; length of stay; postoperative complication; rehabilitation; robotic-assisted laparoscopic prostatectomy.

Conflict of interest statement

Declaration of conflicting interest: The authors declare that there is no conflict of interest.

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Source: PubMed

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