Evaluating physical functioning in critical care: considerations for clinical practice and research

Selina M Parry, Minxuan Huang, Dale M Needham, Selina M Parry, Minxuan Huang, Dale M Needham

Abstract

The evaluation of physical functioning is valuable in the intensive care unit (ICU) to help inform patient recovery after critical illness, to identify patients who may require rehabilitation interventions, and to monitor responsiveness to such interventions. This viewpoint article discusses: (1) the concept of physical functioning with reference to the World Health Organization International Classification of Functioning, Disability and Health; (2) the importance of measuring physical functioning in the ICU; and (3) methods for evaluating physical functioning in the ICU. Recommendations for clinical practice and research are made, along with discussion of future directions.

Keywords: Critical illness; Early mobility; Outcome measurement; Physical function; Physical rehabilitation.

Conflict of interest statement

Ethics approval and consent to participate

Not applicable

Consent for publication

Not applicable

Competing interests

A potential conflict of interest may exist for DMN who is a co-creator of the Functional Status Score for the ICU instrument, which is one of the measurement instruments discussed in this article. The Functional Status Score for the ICU is freely available for non-commercial use as indicated by its Creative Commons licensing. Moreover, DMN is a principal investigator on a NIH-funded, multi-centered randomized trial evaluating nutrition and exercise in acute respiratory failure and, related to this trial, is currently in receipt of an unrestricted research grant and donated amino acid product from Baxter Healthcare Corporation and an equipment loan from Reck Medical Device. DMN and MH received funding from the National Heart, Lung, and Blood Institute (NHLBI) (grant #R24HL111895). SMP reports National Health and Medical Research Council fellowship funding during conduct of this study. SMP and MH declare that they have no competing interests.

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Figures

Fig. 1
Fig. 1
Impact of pre-ICU, critical illness and hospital/ICU factors on body systems related to physical functioning. Pre-ICU, critical illness, environmental factors, and body-system impairments, have interdependent effects on physical functioning (e.g., ICU culture regarding sedation may lead to neurological impairment resulting in immobility and musculoskeletal impairment)
Fig. 2
Fig. 2
Factors to consider when selecting an outcome measure
Fig. 3
Fig. 3
Recommendations for Clinical Practice – Measurement of Physical Functioning. Abbreviations: ADL activities of daily living; BPS Behavioural Pain Scale; CAM-ICU Confusion assessment method for the ICU; CPAx Chelsea Physical assessment Tool; CPOT Critical Care Pain Observation Tool; FSS-ICU Functional Status Score for the ICU; IADL instrumented activities of daily living; ICU intensive care unit; ICDSC Intensive Care Delirium Screening Checklist; IMS ICU Mobility Scale; NRS Numerical rating scale; PFIT-s Physical Function in ICU Test-scored; RASS Richmond Agitation and Sedation Scale; SAS, Sedation Agitation Scale

References

    1. Iwashyna TJ, Ely EW, Smith DM, Langa KM. Long-term cognitive impairment and functional disability among survivors of severe sepsis. JAMA. 2010;304(16):1787–94. doi: 10.1001/jama.2010.1553.
    1. Jolley S, Bunnell A, Hough C. Intensive care unit acquired weakness. Chest. 2016;S0012-3692(16):47575–6.
    1. Needham DM, Davidson J, Cohen H, Hopkins RO, Weinert C, Wunsch H, et al. Improving long-term outcomes after discharge from intensive care unit: report from a stakeholders' conference. Crit Care Med. 2012;40:502–9. doi: 10.1097/CCM.0b013e318232da75.
    1. Puthucheary ZA, Rawal J, McPhail M, Connolly B, Ratnayake G, Chan P, et al. Acute skeletal muscle wasting in critical illness. JAMA. 2013;310(15):1591–70. doi: 10.1001/jama.2013.278481.
    1. Parry SM, El-Ansary D, Cartwright MS, Sarwal A, Berney S, Koopman R, et al. Ultrasonography in the intensive care setting can be used to detect changes in the quality and quantity of muscle and is related to muscle strength and function. J Crit Care. 2015;30(5):1151.e9–14. doi: 10.1016/j.jcrc.2015.05.024.
    1. De Jonghe B, Sharshar T, Lefaucheur J, Authier F, Durand-Zaleski I, Boussarsar M, et al. Paresis acquired in the intensive care unit: a prospective multicenter study. J Am Medical Assoc. 2002;288(9):2859–67. doi: 10.1001/jama.288.22.2859.
    1. Fan E, Dowdy DW, Colantuoni E, Mendez-Tellez P, Sevransky JE, Shanholtz C, et al. Physical complications in acute lung injury survivors: a 2-year longitudinal prospective study. Crit Care Med. 2014;42(4):849–59. doi: 10.1097/CCM.0000000000000040.
    1. Appleton R, Kinsella J, Quasim T. The incidence of intensive care unit-acquired weakness syndromes: a systematic review. J Intensive Care Soc. 2015;16(2):126–36. doi: 10.1177/1751143714563016.
    1. Tennila A, Salmi T, Pettila V, Roine RO, Varpula T, Takkunen O. Early signs of critical illness polyneuropathy in ICU patients with systemic inflammatory response syndrome or sepsis. Intensive Care Med. 2000;26(9):1360–3. doi: 10.1007/s001340000586.
    1. Berek K, Margreiter J, Willeit J, Berek A, Schmutzhard E, Mutz NJ. Polyneuropathies in critically ill patients: a prospective evaluation. Intensive Care Med. 1996;22(9):849–55. doi: 10.1007/BF02044106.
    1. De Jonghe B, Cook D, Sharshar T, Lefaucheur J, Carlet J, Outin H. Acquired neuromuscular disorders in critically ill patients: a systematic review. Intensive Care Med. 1998;24:9. doi: 10.1007/s001340050757.
    1. Herridge MS, Chu LM, Matte A, Tomlinson G, Chan L, Thomas C, et al. The RECOVER Program: disability risk groups and one year outcome after ≥7 days of mechanical ventilation. Am J Respir Crit Care Med. 2016.
    1. Hermans G, Van Mechelen H, Clerckx B, Vanhullebusch T, Mesotten D, Wilmer A, et al. Acute outcomes and 1-year mortality of intensive care unit-acquired weakness. A cohort study and propensity-matched analysis. Am J Respir Crit Care Med. 2014;190(4):410–20. doi: 10.1164/rccm.201312-2257OC.
    1. Parker A, Huang M, Colantuoni E, Lord R, Dinglas V, Chong A, et al. Health care resource use and costs in long-term survivors of ARDS: a 5-year longitudinal cohort study. Crit Care Med. 2017;45(2):196–204.
    1. World Health Organisation . Towards a common language for functioning, disability and health. Geneva: WHO; 2002.
    1. Needham D, Wozniak A, Hough C, Morris P, Dinglas V, Jackson J, et al. Risk factors for physical impairments after acute lung injury in a national multicenter study. AJRCCM. 2014;189(10):1214–24.
    1. Herridge MS, Tansey CM, Matté A, Tomlinson G, Diaz-Granados N, Cooper A, et al. Functional disability 5 years after acute respiratory distress syndrome. N Engl J Med. 2011;364(14):1293–304. doi: 10.1056/NEJMoa1011802.
    1. Iwashyna TJ. Trajectories of recovery and dysfunction after acute illness, with implications for clinical trial design. Am J Respir Crit Care Med. 2012;186(4):302–4. doi: 10.1164/rccm.201206-1138ED.
    1. Iwashyna T, Hodgson C, Pilcher D, Bailey M, van Lint A, Chavan S, et al. Timing of onset and burden of persistent critical illness in Australia and New Zealand: a retrospective population based observational study. Lancet Respir Med. 2016;4(7):566–73. doi: 10.1016/S2213-2600(16)30098-4.
    1. Parry S, Granger C, Berney S, Jones J, Beach L, El-Ansary D, et al. Assessment of impairment and activity limitations in the critically ill: a systematic review of measurement instruments and their clinimetric properties. ICM. 2015;41(5):744–62.
    1. Connolly B. Describing and measuring recovery and rehabilitation after critical illness. Curr Opinion Crit Care. 2015;21:445–52. doi: 10.1097/MCC.0000000000000233.
    1. Portney LG, Watkins MP. Foundations of clinical research, applications to practice. 3. Conneticut: Appleton and Lange; 2009.
    1. Roach K, Van Dillen L. Development of an Acute Care Index of Functional status for patients with neurologic impairment. Phys Ther. 1988;68(7):1102–8. doi: 10.1093/ptj/68.7.1102.
    1. De Morton N, Davidson M, Keating J. The de Morton Mobility Index (DEMMI): an essential health index for an ageing world. Health Qual Life Outcomes. 2008;19(6):63. doi: 10.1186/1477-7525-6-63.
    1. Guralnik JM, Simonsick EM, Ferrucci L, Glynn RJ, Berkman LF, Blazer DG, et al. A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol. 1994;49(2):M85–94. doi: 10.1093/geronj/49.2.M85.
    1. Parry S, Denehy L, Beach L, Berney S, Williamson H, Granger C. Functional outcomes in ICU—what should we be using? An observational study. Crit Care. 2015;19:127. doi: 10.1186/s13054-015-0829-5.
    1. Barr J, Fraser GL, Puntillo K, Ely EW, Gelinas C, Dasta JF, et al. Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit: executive summary. Am J Health Syst Pharm. 2013;70(1):53–8.
    1. Muscedere J, Waters B, Varambally A, Bagshaw S, Boyd J, Maslove D, et al. The impact of frailty on intensive care unit outcomes: a systematic review and meta-analysis. Intensive Care Med. 2017;43(8):1105–22. doi: 10.1007/s00134-017-4867-0.
    1. Kho M, Truong A, Zanni J, Ciesla N, Brower R, Palmer J, et al. Neuromuscular electrical stimulation in mechanically ventilated patients: a randomized sham-controlled pilot trial with blinded outcome assessment. J Crit Care. 2015;30(1):32–9. doi: 10.1016/j.jcrc.2014.09.014.
    1. Nordon-Craft A, Schenkman M, Edbrooke L, Malone D, Moss M, Denehy L. The Physical Function Intensive Care Test: implementation in survivors of critical illness. Phys Ther. 2014;94:1499–507. doi: 10.2522/ptj.20130451.
    1. Huang M, Chan K, Zanni J, Parry S, Neto S, da Silva V, et al. Functional status score for the intensive care unit (FSS-ICU): an international clinimetric analysis of validity, responsiveness and minimal important difference. Crit Care Med. 2016;44(120):e1155–64.
    1. Bissett B, Green M, Marzano V, Byrne S, Leditschke I, Needman T, et al. Reliability and utility of the acute care index of function in intensive care patients: an observational study. Heart Lung. 2016;45:10–4. doi: 10.1016/j.hrtlng.2015.09.008.
    1. Corner E, Wood H, Englebretsen C, Thomas A, Grant R, Nikoletou D, et al. The Chelsea critical care physical assessment tool (CPAx): validation of an innovative new tool to measure physical morbidity in the general adult critical care population: an observational proof of concept pilot study. Physiotherapy. 2013;99:33–41. doi: 10.1016/j.physio.2012.01.003.
    1. Corner E, Handy J, Brett S. E-learning to facilitate the education and implementation of the Chelsea Critical Care Physical Assessment: a novel measure of function in critical illness. BMJ Open. 2016;6:e010614. doi: 10.1136/bmjopen-2015-010614.
    1. Corner E, Soni N, Handy J, Brett S. Construct validity of the Chelsea Critical Care Physical Assessment tool: an observational study of recovery from critical illness. Crit Care. 2014;18:R55. doi: 10.1186/cc13801.
    1. Corner EJ, Hichens LV, Attrill KM, Vizcaychipi MP, Brett SJ, Handy JM. The responsiveness of the Chelsea Critical Care Physical Assessment tool in measuring functional recovery in the burns critical care population: an observational study. Burns. 2015;41(2):241–7. doi: 10.1016/j.burns.2014.12.002.
    1. Twose P, Wise M, Enright S. Critical care functional rehabilitation outcome measure: developing a validated measure. Physiother Theory Pract. 2015;31:474–82. doi: 10.3109/09593985.2015.1025320.
    1. Sommers J, Vredeveld T, Lindeboom R, Nollet F, Engelbert R, van der Schaaf M. The De Morton Mobility Index is feasible, reliable and valid in critically ill patients. Phys Ther. 2016;96(10):1658–66.
    1. Zanni J, Korupolu R, Fan E, Pradhan P, Janjua K, Palmer J, et al. Rehabilitation therapy and outcomes in acute respiratory failure: an observational pilot project. J Crit Care. 2010;25:254–62. doi: 10.1016/j.jcrc.2009.10.010.
    1. Ragavan V, Greenwood K, Bibi K. The Functional Status Score for the Intensive Care Unit Scale: is it reliable in the intensive care unit? Can it be used to determine discharge placement? JAcute Care Physical Ther. 2016;7(3):93–100. doi: 10.1097/JAT.0000000000000030.
    1. Maldaner da Silva V, Neto J, Cipriano G, Pinedo M, Needham D, Zanni J, et al. Brazilian version of the Functional Status Score for the ICU: translation and cross-cultural adaptation. Revista Brasileira de Terapia Intensiva. 2017;29(1):34–8.
    1. Thrush A, Rozek M, Dekerlegand J. The clinical utility of the functional status score for the intensive care unit (FSS-ICU) at a long term acute care hospital: a prospective cohort study. Phys Ther. 2012;92:1536–45. doi: 10.2522/ptj.20110412.
    1. Hodgson C, Needham D, Haines K, Bailey M, Ward A, Harrold M, et al. Feasibility and inter-rater reliability of the ICU Mobility Scale. Heart Lung. 2014;43(1):19–24. doi: 10.1016/j.hrtlng.2013.11.003.
    1. Kawaguchi W, Nawa R, Figueiredo T, Martins L, Pires-Neto R. Perme Intensive Care Unit Mobility Score and ICU Mobility Scale: translation into Portugese and cross-cultural adaptation for use in Brazil. Journal Brasileiro de Pneumologia. 2016;42(6):429–34. doi: 10.1590/s1806-37562015000000301.
    1. Tipping C, Bailey M, Bellomo R, Berney S, Buhr H, Denehy L, et al. The ICU Mobility scale has construct and predictive validity and is responsive: a multi-centre observational study. Ann Am Thoracic Soc. 2016;13(6):887–93.
    1. McWilliams D, Atkins G, Hodson J, Boyers M, Lea T, Snelson C. Feasibility and reliability of the Manchester Mobility Score as a measure of physical function within the intensive care unit. ACPRC J. 2016; in press.
    1. Denehy L, De Morton N, Skinner E, Edbrooke L, Haines K, Warrillow S, et al. A Physical Function test for use in the intensive care unit: validity, responsiveness, and predictive utility of the physical function ICU test (scored) Phys Ther. 2013;93:1636–45. doi: 10.2522/ptj.20120310.
    1. Skinner EH, Berney S, Warrillow S, Denehy L. Development of a physical function outcome measure (PFIT) and a pilot exercise training protocol for use in intensive care. Crit Care Resusc. 2009;11(2):110–5.
    1. Perme C, Nawa R, Winkelman C, Masud F. A tool to assess mobility status in critically ill patients: the Perme Mobility Score. Methodist Debakey Cardiovasc J. 2014;10(1):41–9. doi: 10.14797/mdcj-10-1-41.
    1. Nawa RK, Lettvin C, Winkelman C, Evora PRB, Perme C. Initial inter-rater reliability for a novel measure of patient mobility in a cardiovascular ICU. J Crit Care. 2014;29(3):475.e1–5.
    1. Garzon-Serrano J, Ryan C, Waak K, Hirschberg R, Tully S, Bittner E, et al. Early mobilization in critically ill patients: patients' mobilization level depends on health care provider's profession. Physical Med Rehabil. 2011;3(4):307–13.
    1. Schaller S, Stauble C, Susemasa M, Heim M, Duarte I, Mensch O, et al. The German validation study of the surgical intensive care unit optimal mobility score. J Crit Care. 2016;32:201–6. doi: 10.1016/j.jcrc.2015.12.020.
    1. Kasotakis G, Schmidt U, Perry D, Grosse-Sundrup M, Benjamin J, Ryan C, et al. The surgical intensive care unit optimal mobility scale predicts mortality and length of stay. Crit Care. 2012;40:1122–8. doi: 10.1097/CCM.0b013e3182376e6d.
    1. Piva S, Dora G, Minelli C, Michelini M, Turla F, Mazza S, et al. The surgical optimal mobility score predicts mortality and length of stay in an Italian population of medical, surgical and neurologic intensive care unit patients. J Crit Care. 2015;30:1251–7. doi: 10.1016/j.jcrc.2015.08.002.

Source: PubMed

3
订阅