Applications of Propolis in Dentistry: A Review

Amir Jalal Abbasi, Farnoush Mohammadi, Mohamad Bayat, Shimelis Megersa Gema, Hannaneh Ghadirian, Hasti Seifi, Hananeh Bayat, Naghmeh Bahrami, Amir Jalal Abbasi, Farnoush Mohammadi, Mohamad Bayat, Shimelis Megersa Gema, Hannaneh Ghadirian, Hasti Seifi, Hananeh Bayat, Naghmeh Bahrami

Abstract

Background: Propolis is a resinous substance obtained from the beehives that has antioxidant, anti-bacteria, anti-virus, anti-fungal, anti-tumor and anti-inflammatory activity. The aim of this study was to review the studies about the role of propolis in improving dental and oral health.

Methods: This study reviewed the published articles regarding the applications of propolis in dentistry. An electronic search of the literature was carried out in Farsi electronic databases including Google, Medlib.ir, SID, Iranmedex and Magiran as well as English electronic databases such as PubMed and ISI Web of Knowledge. These databases were searched for articles published between 1997 and October 20, 2017. Non-dental books and journals were also manually searched.

Results: This study reviewed published articles on the efficacy of propolis for surgical wound healing, caries prevention, treatment of dentin hypersensitivity, treatment of aphthous ulcers and propolis as a storage medium for avulsed teeth, root canal irrigating solution and mouthwash.

Conclusion: The result of the reviewed article showed that propolis is effective an agent that is used for multiple purpose in oral health.

Keywords: Dentistry; Honeybee; Oral health; Propolis.

References

    1. Wander P. Taking the sting out of dentistry. Dental Practice. 1995;25(1995):3–4.
    1. Krol W, Czuba Z, Scheller S, Gabrys J, Grabiec S, Shani J. Anti-oxidant property of ethanolic extract of propolis (EEP) as evaluated by inhibiting the chemiluminescence oxidation of luminol. Biochemistry International. 1990;21(4):593–597.
    1. Velazquez C, Navarro M, Acosta A, Angulo A, Dominguez Z, Robles R, et al. Antibacterial and free-radical scavenging activities of Sonoran propolis. Journal of Applied Microbiology. 2007;103(5):1747–1756.
    1. Park YK, Alencar SM, Aguiar CL. Botanical origin and chemical composition of Brazilian propolis. Journal of Agricultural and Food Chemistry. 2002;50(9):2502–2506.
    1. Seidel V, Peyfoon E, Watson DG, Fearnley J. Comparative study of the antibacterial activity of propolis from different geographical and climatic zones. Phytotherapy Research. 2008;22(9):1256–1263.
    1. Orsi R, Sforcin J, Rall V, Funari S, Barbosa L, Fernandes J. Susceptibility profile of Salmonella against the antibacterial activity of propolis produced in two regions of Brazil. Journal of Venomous Animals and Toxins including Tropical Diseases. 2005;11(2):109–116.
    1. Ikeno K, Ikeno T, Miyazawa C. Effects of propolis on dental caries in rats. Caries Research. 1991;25(5):347–351.
    1. Koru O, Toksoy F, Acikel CH, Tunca YM, Baysallar M, Guclu AU, et al. In vitro antimicrobial activity of propolis samples from different geographical origins against certain oral pathogens. Anaerobe. 2007;13(3):140–145.
    1. Kujumgiev A, Tsvetkova I, Serkedjieva Y, Bankova V, Christov R, Popov S. Antibacterial, antifungal and antiviral activity of propolis of different geographic origin. Journal of ethnopharmacology. 1999;64(3):235–240.
    1. Borrelli F, Maffia P, Pinto L, Ianaro A, Russo A, Capasso F, et al. Phytochemical compounds involved in the anti-inflammatory effect of propolis extract. Fitoterapia. 2002;73:S53–S63.
    1. Poppe B, Michaelis H. Results of a twice-yearly controlled oral hygiene activity using a propolis-containing toothpaste (double-blind study) Stomatologie der DDR. 1986;36(4):195–203.
    1. Dodwad V, Kukreja BJ. Propolis mouthwash: A new beginning. Journal of Indian Society of Periodontology. 2011;15(2):121.
    1. Cowan M. Plant products as antimicrobial agents. Clin Microbial Rev. 1999;22:564–582.
    1. Lotfy M. Biological activity of bee propolis in health and disease. Asian Pac J Cancer Prev. 2006;7(1):22–31.
    1. Magro FILHO O, de CARVALHO ACP. Application of propolis to dental sockets and skin wounds. The Journal of Nihon University School of Dentistry. 1990;32(1):4–13.
    1. Olczyk P, Wisowski G, Komosinska-Vassev K, Stojko J, Klimek K, Olczyk M, et al. Propolis modifies collagen types I and III accumulation in the matrix of burnt tissue. Evidence-Based Complementary and Alternative Medicine. 2013 2013.
    1. Martin MP, Pileggi R. A quantitative analysis of Propolis: a promising new storage media following avulsion. Dental traumatology. 2004;20(2):85–89.
    1. Özan F, Polat ZA, Er K, Özan Ü, Değer O. Effect of propolis on survival of periodontal ligament cells: new storage media for avulsed teeth. Journal of Endodontics. 2007;33(5):570–573.
    1. Gopikrishna V, Baweja PS, Venkateshbabu N, Thomas T, Kandaswamy D. RETRACTED: Comparison of Coconut Water, Propolis, HBSS, and Milk on PDL Cell Survival. Journal of Endodontics. 2008;34(5):587–589.
    1. Al-Shaher A, Wallace J, Agarwal S, Bretz W, Baugh D. Effect of propolis on human fibroblasts from the pulp and periodontal ligament. Journal of endodontics. 2004;30(5):359–361.
    1. Al-Qathami H, Al-Madi E. Comparison of sodium hypochlorite, propolis and saline as root canal irrigants: A pilot study. Saudi Dent J. 2003;15(2):100–103.
    1. Kandaswamy D, Venkateshbabu N, Gogulnath D, Kindo A. Dentinal tubule disinfection with 2% chlorhexidine gel, propolis, morinda citrifolia juice, 2% povidone iodine, and calcium hydroxide. International endodontic journal. 2010;43(5):419–423.
    1. Oncag O, Cogulu D, Uzel A, Sorkun K. Efficacy of propolis as an intracanal medicament against Enterococcus faecalis. General dentistry. 2006;54(5):319–322.
    1. Awawdeh L, AL-Beitawi M, Hammad M. Effectiveness of propolis and calcium hydroxide as a short-term intracanal medicament against Enterococcus faecalis: A laboratory study. Australian Endodontic Journal. 2009;35(2):52–58.
    1. Rezende GPdSR, Costa LRdRS, Pimenta FC, Baroni DA. In vitro antimicrobial activity of endodontic pastes with propolis extracts and calcium hydroxide: a preliminary study. Brazilian dental journal. 2008;19(4):301–305.
    1. Özan F, Sümer Z, Polat ZA, Er K, Özan Ü, Deḡer O. Effect of mouthrinse containing propolis on oral microorganisms and human gingival fibroblasts. European journal of dentistry. 2007;1(4):195.
    1. Fearnley J. Bee propolis: natural healing from the hive. Souvenir. 2001
    1. Hayacibara MF, Koo H, Rosalen PL, Duarte S, Franco EM, Bowen WH, et al. In vitro and in vivo effects of isolated fractions of Brazilian propolis on caries development. Journal of Ethnopharmacology. 2005;101(1):110–115.
    1. Koo H, Rosalen PL, Cury JA, Park YK, Bowen WH. Effects of compounds found in propolis on Streptococcus mutans growth and on glucosyltransferase activity. Antimicrobial agents and chemotherapy. 2002;46(5):1302–1309.
    1. Mahmoud A, Almas K, Dahlan A. The effect of propolis on dentinal hypersensitivity and level of satisfaction among patients from a university hospital Riyadh, Saudi Arabia. Indian journal of dental research: official publication of Indian Society for Dental Research. 1999;10(4):130–137.
    1. Murray M, Worthington H, Blinkhorn A. A study to investigate the effect of a propolis-containing mouthrinse on the inhibition of de novo plaque formation. Journal of Clinical Periodontology. 1997;24(11):796–798.
    1. Koo H, Cury JA, Rosalen PL, Ambrosano GM, Ikegaki M, Park YK. Effect of a mouthrinse containing selected propolis on 3-day dental plaque accumulation and polysaccharide formation. Caries Research. 2002;36(6):445–448.
    1. Scheller S, Nolewajka E, Panasiewicz M, Dziekanowska D, Tustanowski J, Stojko A. Biological properties and clinical application of propolis. IV. The action of ethanol extract of propolis (EEP) on cells cultured in vitro. Arzneimittel-Forschung. 1977;27(8):1547.
    1. Bassani-Silva S, Sforcin JM, Amaral AS, Gaspar LF, Rocha NS. Propolis effect in vitro on canine transmissible venereal tumor cells. Revista Portuguesa de Ciências Veterinárias. 2007;102(563/564):261–265.
    1. Bufalo MC, Candeias JM, Sforcin JM. In vitro cytotoxic effect of Brazilian green propolis on human laryngeal epidermoid carcinoma (HEp-2) cells. Evidence-Based Complementary and Alternative Medicine. 2009;6(4):483–487.
    1. Sforcin J. Propolis and the immune system: a review. Journal of ethnopharmacology. 2007;113(1):1–14.
    1. Sulaiman GM, Ad'hiah AH, Al-Sammarrae KW, Bagnati R, Frapolli R, Bello E, et al. Assessing the anti-tumour properties of Iraqi propolis in vitro and in vivo. Food and chemical toxicology. 2012;50(5):1632–1641.
    1. Chirumbolo S. Flavonoids in propolis acting on mast cell-mediated wound healing. Inflammopharmacology. 2012;20(2):99–101.
    1. Viuda-Martos M, Ruiz-Navajas Y, Fernández-López J, Pérez-Álvarez J. Functional properties of honey, propolis, and royal jelly. Journal of food science. 2008;73(9)
    1. Burdock G. Review of the biological properties and toxicity of bee propolis (propolis) Food and Chemical toxicology. 1998;36(4):347–363.
    1. Walgrave SE, Warshaw EM, Glesne LA. Allergic contact dermatitis from propolis. Dermatitis. 2005;16(4):209–215.

Source: PubMed

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