The CAIDE Dementia Risk Score App: The development of an evidence-based mobile application to predict the risk of dementia

Shireen Sindi, Elisabeth Calov, Jasmine Fokkens, Tiia Ngandu, Hilkka Soininen, Jaakko Tuomilehto, Miia Kivipelto, Shireen Sindi, Elisabeth Calov, Jasmine Fokkens, Tiia Ngandu, Hilkka Soininen, Jaakko Tuomilehto, Miia Kivipelto

Abstract

Background: The CAIDE (Cardiovascular Risk Factors, Aging, and Incidence of Dementia) Dementia Risk Score is a validated tool to predict late-life dementia risk (20 years later), based on midlife vascular risk factors. The goal was to render this prediction tool widely accessible.

Methods: The CAIDE Risk Score (mobile application) App was developed based on the CAIDE Dementia Risk Score, involving information on age, educational level, hypertension, hypercholesterolemia, obesity, and physical inactivity.

Results: The CAIDE Risk Score App is an evidence-based practical tool, which allows users to detect their individual risk, provides guidance for risk modification, and suggests consulting a health care practitioner if needed. Moreover, it allows practitioners to discuss preventive measures and monitor risk reduction.

Conclusions: The CAIDE Risk Score App is the first to predict the risk for dementia through an important evidence-based tool. The App can encourage users to actively decrease their modifiable risk factors and postpone cognitive impairment and dementia.

Keywords: Dementia prediction; Dementia prevention; Dementia risk score; Mobile applications; Mobile health; Vascular risk factors.

Figures

Fig. 1
Fig. 1
Receiver-operating characteristic curves showing the performance of the dementia risk scores in predicting the risk of dementia in 20 years among those in middle age. The AUC for model 1 was 0.769 (95% CI: 0.709–0.829). The AUC for model 2 was 0.776 (95% CI: 0.717–0.836). (Figure adapted from .) Abbreviation: CI, confidence interval.
Fig. 2
Fig. 2
CAIDE Risk Score App screenshot displaying the demographic information required for calculation of the risk score. Abbreviations: CAIDE, Cardiovascular Risk Factors, Aging, and Incidence of Dementia; BP, blood pressure.
Fig. 3
Fig. 3
CAIDE Risk Score App screenshot showing a graphic representation of the risk score. Abbreviations: CAIDE, Cardiovascular Risk Factors, Aging, and Incidence of Dementia; BP, blood pressure.
Fig. 4
Fig. 4
Explanation of the increased risk score. Abbreviation: BP, blood pressure.

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Source: PubMed

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