The Likelihood of Developing a Carbapenem-Resistant Enterobacteriaceae Infection during a Hospital Stay
Pranita D Tamma, Abida Kazmi, Yehudit Bergman, Katherine E Goodman, Ernest Ekunseitan, Joe Amoah, Patricia J Simner, Pranita D Tamma, Abida Kazmi, Yehudit Bergman, Katherine E Goodman, Ernest Ekunseitan, Joe Amoah, Patricia J Simner
Abstract
Of 1,455 unique patients in U.S. intensive care units (ICUs), 4% were rectally colonized with CRE on admission. A total of 297 patients were initially negative for carbapenem-resistant Enterobacteriaceae (CRE) and remained in the ICU long enough to contribute additional swabs; 22% of these patients had a subsequent CRE-positive swab, with a median time to CRE colonization of 13 days (interquartile range, 7 to 21 days). Patients colonized with carbapenemase-producing CRE were more likely than those colonized with non-carbapenemase-producing CRE to develop CRE infections during their hospitalizations (36% versus 3%; P < 0.05).
Keywords: CRE; ICU; carbapenem resistance; multidrug-resistant organisms.
Copyright © 2019 American Society for Microbiology.
Source: PubMed