Dare to jump: The effect of the new high impact activity SuperJump on bone remodeling. A new tool to maintain fitness during COVID-19 home confinement

Sonya Vasto, Alessandra Amato, Patrizia Proia, Rosalia Caldarella, Cristina Cortis, Sara Baldassano, Sonya Vasto, Alessandra Amato, Patrizia Proia, Rosalia Caldarella, Cristina Cortis, Sara Baldassano

Abstract

SuperJump is a high impact activity performed on an elastic trampoline that mixes aerobic and anaerobic exercises already proposed as home-based activity for preventing a sedentary lifestyle. We determined in a randomized controlled trial whether 20 weeks of SuperJump activity would promote bone formation and reduce resorption in eumenorrheic women. Twenty-four women were randomized to a non-exercise group (control group) or an exercise group that performed SuperJump activity three times a week for 20 weeks. Blood samples were collected in both groups at baseline and at the end of the 20 weeks and compared within and between the groups for C-terminal telopeptide (CTX), a marker of bone resorption, osteocalcin, a marker of bone formation, and the markers of bone metabolism parathyroid hormone (PTH), calcitonin, albumin-adjusted calcium (Aa calcium), vitamin D, phosphate and potassium. After 20 weeks of SuperJump activity, levels of CTX were significantly reduced while levels of osteocalcin were increased. PTH, calcium and potassium were involved in the mechanism of action because PTH was reduced while calcium and potassium were increased. Calcitonin, vitamin D and phosphate levels did not change. These data suggest that SuperJump activity is able to reduce bone resorption and improve bone formation by acting on essential regulators of bone metabolism. They also suggest that SuperJump training may be used as a valuable intervention to prevent the occurrence of osteoporosis in aging because it improves bone homeostasis in favor of bone formation and could counteract a sedentary lifestyle, such as during COVID-19 home confinement, which could itself contribute to the variation of bone metabolism. Trial registration: Clinicaltrials.gov NCT04942691 -retrospectively registered.

Keywords: Bone homeostasis; Bone remodeling; Osteoporosis prevention; Physical activity; Women.

Conflict of interest statement

The authors report no conflict of interest.

Copyright © Biology of Sport 2022.

Figures

FIG. 1
FIG. 1
Flow chart of the recruitment and selection process of subjects.
FIG. 2
FIG. 2
Schematic overview of the study design. Blood samples were collected at time 0 (baseline) and after 20 weeks in the control group and exercise group. In the exercise group, SuperJump training was performed three times a week, each session lasting 60 minutes for a total of 20-weeks. The control group not performed physical activity.
FIG. 3
FIG. 3
Markers of bone remodeling measured baseline and after 20 weeks in the control group and exercise group. (A) Box and whisker plot of CTX, marker of bone resorption (B) Box and whisker plot of Osteocalcin, marker of bone formation.
FIG. 4
FIG. 4
Markers of bone metabolism measured baseline and 20 weeks in the control group and exercise group. (A) Box and whisker plot of PTH (B) Box and whisker plot of Aa Calcium (C) Box and whisker plot of Calcitonin (D) Box and whisker plot of Vitamin D (E) Box and whisker plot of Phosphate (F) Box and whisker plot of Potassium.

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Source: PubMed

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