Should RT-PCR be considered a gold standard in the diagnosis of COVID-19?

Moustapha Dramé, Maturin Tabue Teguo, Emeline Proye, Fanny Hequet, Maxime Hentzien, Lukshe Kanagaratnam, Lidvine Godaert, Moustapha Dramé, Maturin Tabue Teguo, Emeline Proye, Fanny Hequet, Maxime Hentzien, Lukshe Kanagaratnam, Lidvine Godaert

No abstract available

Keywords: COVID-19; RT-PCR; diagnosis; gold standard; serology.

Conflict of interest statement

The authors declare that there are no conflict of interests.

References

    1. Liu R, Han H, Liu F, et al. Positive rate of RT‐PCR detection of SARS‐CoV‐2 infection in 4880 cases from one hospital in Wuhan, China, from Jan to Feb 2020. Clin Chim Acta. 2020;505:172‐175.
    1. Xie J, Ding C, Li J, et al. Characteristics of patients with coronavirus disease (COVID‐19) confirmed using an IgM‐IgG antibody test [published online ahead of print April 24, 2020]. J Med Virol. 2020.
    1. Liu K, Chen Y, Lin R, Han K. Clinical features of COVID‐19 in elderly patients: a comparison with young and middle‐aged patients [published online ahead of print March 27, 2020]. J Infect. 2020;80(6):e14‐e18.
    1. Cassaniti I, Novazzi F, Giardina F, et al. Performance of VivaDiag COVID‐19 IgM/IgG rapid test is inadequate for diagnosis of COVID‐19 in acute patients referring to emergency room department [published online ahead of print March 30, 2020]. J Med Virol. 2020.
    1. Xiang F., Wang X., He X., et al. Antibody detection and dynamic characteristics in patients with COVID‐19 [published online ahead of print April 19, 2020]. Clin Infect Dis. 2020.
    1. Ai T, Yang Z, Hou H, et al. Correlation of chest CT and RT‐PCR testing in coronavirus disease 2019 (COVID‐19) in China: a report of 1014 cases [published online ahead of print February 26, 2020]. Radiology. 2020.
    1. Majidi H., Niksolat F. Chest CT in patients suspected of COVID‐19 infection: a reliable alternative for RT‐PCR. Am J Emerg Med. 2020.
    1. Cohen J. A coefficient of agreement for nominal scales. Educ Psychol Meas. 1960;20:27‐46.
    1. Duggan PF. Time to abolish "gold standard". BMJ. 1992;304:1568‐1569.
    1. Versi E. "Gold standard" is an appropriate term. BMJ. 1992;305(6846):187.

Source: PubMed

3
订阅