Randomized controlled trial of a positive affect intervention for people newly diagnosed with HIV

Judith T Moskowitz, Adam W Carrico, Larissa G Duncan, Michael A Cohn, Elaine O Cheung, Abigail Batchelder, Lizet Martinez, Eisuke Segawa, Michael Acree, Susan Folkman, Judith T Moskowitz, Adam W Carrico, Larissa G Duncan, Michael A Cohn, Elaine O Cheung, Abigail Batchelder, Lizet Martinez, Eisuke Segawa, Michael Acree, Susan Folkman

Abstract

Objective: We conducted a randomized controlled trial to determine whether IRISS (Intervention for those Recently Informed of their Seropositive Status), a positive affect skills intervention, improved positive emotion, psychological health, physical health, and health behaviors in people newly diagnosed with HIV.

Method: One-hundred and fifty-nine participants who had received an HIV diagnosis in the past 3 months were randomized to a 5-session, in-person, individually delivered positive affect skills intervention or an attention-matched control condition.

Results: For the primary outcome of past-day positive affect, the group difference in change from baseline over time did not reach statistical significance (p = .12, d = .30). Planned secondary analyses within assessment point showed that the intervention led to higher levels of past-day positive affect at 5, 10, and 15 months postdiagnosis compared with an attention control. For antidepressant use, the between group difference in change from baseline was statistically significant (p = .006, d = -.78 baseline to 15 months) and the difference in change over time for intrusive and avoidant thoughts related to HIV was also statistically significant (p = .048, d = .29). Contrary to findings for most health behavior interventions in which effects wane over the follow up period, effect sizes in IRISS seemed to increase over time for most outcomes.

Conclusions: This comparatively brief positive affect skills intervention achieved modest improvements in psychological health, and may have the potential to support adjustment to a new HIV diagnosis. (PsycINFO Database Record

Trial registration: ClinicalTrials.gov NCT00720733.

(c) 2017 APA, all rights reserved).

Figures

Figure 1
Figure 1
CONSORT diagram
Figure 2A. Effect sizes ( d )…
Figure 2A. Effect sizes (d) for between group changes from baseline: Psychological Health
For binary outcome variables, effect sizes were first calculated as odds ratios and converted to Cohen's d following Borenstein, Hedges, Higgins, & Rothstein (2009) for ease of interpretation across outcome variables. PA = Positive affect; NA = Negative Affect; CES-D = the Center for Epidemiological Studies Depression Scale; IES = Impact of Events Scale
Figure 2B. Effect Sizes ( d )…
Figure 2B. Effect Sizes (d) for between group change from baseline: Physical Health and Health Behaviors
For binary outcome variables, effect sizes were first calculated as odds ratios and converted to Cohen's d following Borenstein, Hedges, Higgins, & Rothstein (2009) for ease of interpretation across outcome variables. VL = viral load; ART = Antiretroviral Therapy

Source: PubMed

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