Multidisciplinary integrated headache care: a prospective 12-month follow-up observational study

Thomas-Martin Wallasch, Peter Kropp, Thomas-Martin Wallasch, Peter Kropp

Abstract

This prospective study investigated the effectiveness of a three-tier modularized out- and inpatient multidisciplinary integrated headache care program. N = 204 patients with frequent headaches (63 migraine, 11 tension-type headache, 59 migraine + tension-type headache, 68 medication-overuse headache and 3 with other primary headaches) were enrolled. Outcome measures at baseline, 6- and 12-month follow-ups included headache frequency, Migraine Disability Assessment (MIDAS), Hospital Anxiety and Depression Scale (HADS), standardized headache diary and a medication survey. Mean reduction in headache frequency was 5.5 ± 8.5 days/month, p < 0.001 at 6 months' follow-up and 6.9 ± 8.3 days/month, p < 0.001 after 1 year. MIDAS decreased from 53.0 ± 60.8 to 37.0 ± 52.4 points, p < 0.001 after 6 months and 34.4 ± 53.2 points, p < 0.001 at 1 year. 44.0 % patients demonstrated at baseline an increased HAD-score for anxiety and 16.7 % of patients revealed a HAD-score indicating a depression. At the end of treatment statistically significant changes could be observed for anxiety (p < 0.001) and depression (p < 0.006). The intake frequency of attack-aborting medication decreased from 10.3 ± 7.3 days/month at admission to 4.7 ± 4.1 days/month, p < 0.001 after 6 months and reached 3.8 ± 3.5 days/month, p < 0.001 after 1 year. At baseline 37.9 % of patients had experience with non-pharmacological treatments and 87.0 % at 12-month follow-up. In conclusion, an integrated headache care program was successfully established. Positive health-related outcomes could be obtained with a multidisciplinary out- and inpatient headache treatment program.

Figures

Fig. 1
Fig. 1
Course of headache frequency (days/month)

References

    1. Stovner LJ, Hagen K, Jensen R, Katsarava Z, Lipton R, Scher A, Steiner T, Zwart JA. The Global burden of headache: a documentation of headache prevalence and disability worldwide. Cephalalgia. 2007;27:193–210. doi: 10.1111/j.1468-2982.2007.01288.x.
    1. Lantéri-Minet M, Duru G, Mudge M, Cotrell S. Quality of life impairment, disability and economic burden associated with chronic daily headache, focusing on chronic migraine with or without medication overuse: a systematic review. Cephalalgia. 2011;31:837–850. doi: 10.1177/0333102411398400.
    1. Scher AI, Stewart WF, Ricci JA, Lipton RB. Factors associated with the onset and remission of chronic daily headache in a population-based study. Pain. 2003;106:81–89. doi: 10.1016/S0304-3959(03)00293-8.
    1. Jonsson P, Hedenrud T, Linde M. Epidemiology of medication overuse headache in the general Swedish population. Cephalalgia. 2011;31:1015–1022. doi: 10.1177/0333102411410082.
    1. Silberstein SD, Lipton RB, Saper JR. Chronic daily headache, including transformed migraine, chronic tension-type headache, and medication overuse. In: Silberstein SD, Lipton RB, Dodick DW, editors. Wolff’s headache and other head pain. 8. New York: Oxford University Press; 2008. pp. 315–378.
    1. Steiner TJ, Antonaci F, Jensen R, Lainez MJA, Lantéri-Minet M, Valade D. Recommendations for headache service organisation and delivery in Europe. J Headache Pain. 2011;12:419–426. doi: 10.1007/s10194-011-0320-x.
    1. Lipton RB, Diamond S, Reed M, Diamond ML, Stewart WF. Migraine diagnosis and treatment: results from the American Migraine study II. Headache. 2001;41:638–645. doi: 10.1046/j.1526-4610.2001.041007638.x.
    1. Devine JW, Farley JF, Hadsall RS. Patterns and predictors of prescription medication use in the management of headache: findings from the 2000 Medical Expenditure Panel Survey. Headache. 2005;45:1171–1180. doi: 10.1111/j.1526-4610.2005.00240.x.
    1. Pascual J, Lainez MJ, Baos V, Garcia ML, Lopez-Gil A. Predictive model for the Migraine-ACT questionnaire in primary care. Curr Med Res Opin. 2007;23:3033–3039. doi: 10.1185/030079907X242791.
    1. Clouse JC, Osterhaus JT. Healthcare resource use and costs associated with migraine in a managed healthcare setting. Ann Pharmacother. 1994;28:659–664.
    1. Saper JR, Lake AE, Madden SF, Kreeger C. Comprehensive/tertiary care for headache: a 6-month outcome study. Headache. 1999;39:249–263. doi: 10.1046/j.1526-4610.1999.3904249.x.
    1. Lang E, Kastner S, Neundörfer B, Bickel A. Können Therapieempfehlungen die Effektivität der ambulanten Versorgung von Patienten mit Kopfschmerzen verbessern? Schmerz. 2001;15:229–240. doi: 10.1007/s004820100053.
    1. Lemstra M, Stewart B, Olszynski WP. Effectiveness of multidisciplinary intervention in the treatment of migraine: a randomized clinical trial. Headache. 2002;42:845–854. doi: 10.1046/j.1526-4610.2002.02202.x.
    1. Harpole LH, Samsa GP, Jurgelski AE, Shipley JL, Bernstein A, Matchar DB. Headache management program improves outcome for chronic headache. Headache. 2003;43:715–724. doi: 10.1046/j.1526-4610.2003.03128.x.
    1. Maizels M, Saenz V, Wirjo J. Impact of a group-based model of disease management for headache. Headache. 2003;43:621–627. doi: 10.1046/j.1526-4610.2003.03104.x.
    1. Magnusson JE, Riess CM, Becker WJ. Effectiveness of a multidisciplinary treatment program for chronic daily headache. Can J Neurol Sci. 2004;31:72–79.
    1. Zeeberg P, Olesen J, Jensen R. Efficacy of multidisciplinary treatment in a tertiary referral headache centre. Cephalalgia. 2005;25:1159–1167. doi: 10.1111/j.1468-2982.2005.00980.x.
    1. Rothrock JF, Parada VA, Sims C, Key V, Walters NS, Zweifler RM. The impact of intensive patient education on clinical outcome in a clinic-based migraine population. Headache. 2006;46:726–731. doi: 10.1111/j.1526-4610.2006.00428.x.
    1. Mongingi F, Ciccone G, Rota E, Ferrero L, Ugolini A, Evangelista QA, Ceccarelli M, Galassi C. Effectiveness of an educational and physical programme in reducing headache, neck and shoulder pain: a workplace controlled trial. Cephalalgia. 2008;28:541–552. doi: 10.1111/j.1468-2982.2008.01551.x.
    1. Matchar DB, Harpole L, Samsa GP, Jurgelski A, Lipton RB, Silberstein SD, Young W, Kori S, Blumenfeld A. The headache management trial: a randomized study of coordinated care. Headache. 2008;48:1294–1310. doi: 10.1111/j.1526-4610.2007.01148.x.
    1. Lake AE, Saper JR, Hamel RL. Comprehensive inpatient treatment of refractory chronic daily headache. Headache. 2009;49:555–562. doi: 10.1111/j.1526-4610.2009.01364.x.
    1. Gunreben-Stempfe B, Griessinger N, Lang E, Muehlhans B, Sittl R, Ulrich K. Effectiveness of an intensive multidisciplinary headache treatment program. Headache. 2009;49:990–1000. doi: 10.1111/j.1526-4610.2009.01448.x.
    1. Jensen R, Zeeberg P, Dehlendorff C, Olesen J. Predictors of outcome of the treatment programme in a multidisciplinary headache centre. Cephalalgia. 2010;30:1214–1224. doi: 10.1177/0333102410361403.
    1. Gaul C, van Doorn C, Webering N, Dlugay M, Katsarava Z, Diener HC, Fritsche G. Clinical outcome of a headache-specific multidisciplinary treatment program and adherence to treatment recommendations in a tertiary headache center: an observational study. J Headache Pain. 2011;12:475–483. doi: 10.1007/s10194-011-0348-y.
    1. Gaul C, Bromstrup J, Fritsche G, Diener HC, Katsarava Z. Evaluating integrated headache care: a one-year follow-up observational study in patients treated at the Essen headache centre. BMC Neurol. 2011;11:124. doi: 10.1186/1471-2377-11-124.
    1. Baskin SM, Lipchik GL, Smitherman TA. Mood and anxiety disorders in chronic headache. Headache. 2006;46:76–87. doi: 10.1111/j.1526-4610.2006.00559.x.
    1. Wang SJ, Fuh JL, Lu SR, Juang KD. Quality of life differs among headache diagnoses: analysis of SF-36 survey in 901 headache patients. Pain. 2001;89:285–292. doi: 10.1016/S0304-3959(00)00380-8.
    1. Headache Classification Subcommittee of the International Headache Society The International Classification of Headache Disorders: 2nd edition. Cephalalgia. 2004;24:9–160. doi: 10.1111/j.1468-2982.2003.00824.x.
    1. Evers S, May A, Fritsche G, Kropp P, Lampl C, Limmroth V, Malzacher V, Sandor P, Straube A, Diener H-C. Akuttherapie und Prophylaxe der Migräne—Leitlinie der Deutschen Migräne- und Kopfschmerzgesellschaft und der Deutschen Gesellschaft für Neurologie. Nervenheilkunde. 2008;27:933–949.
    1. Straube A, May A, Kropp P, Katsarava Z, Haag G, Lampl C, Sándor PS, Diener H-C, Evers S. Therapie primärer chronischer Kopfschmerzen: Chronische Migräne, chronischer Kopfschmerz vom Spannungstyp und andere chronische tägliche Kopfschmerzen—Evidenzbasierte Empfehlungen der Deutschen Migräne- und Kopfschmerzgesellschaft in Zusammenarbeit mit der Österreichischen Kopfschmerzgesellschaft und der Schweizerischen Kopfwehgesellschaft. Nervenheilkunde. 2007;26:186–199.
    1. Diener HC, Gaul C, Jensen R, Göbel H, Heinze A, Silberstein SD. Integrated headache care. Cephalalgia. 2011;31:1039–1047. doi: 10.1177/0333102411409075.
    1. Stewart WF, Lipton RB, Whyte J, Dowson A, Kolodner K, Liberman JN, Sawyer J. An international study to assess reliability of the Migraine Disability Assessment (MIDAS) score. Neurology. 1999;53:988–994. doi: 10.1212/WNL.53.5.988.
    1. Stewart WF, Lipton RB, Dowson AJ, Sawyer J. Development and testing of the Migraine Disability Assessment (MIDAS) Questionnaire to assess headache-related disability. Neurology. 2001;56:20–28. doi: 10.1212/WNL.56.suppl_1.S20.
    1. Herrmann-Lingen C, Buss U, Snaith RP (2005) Hospital Anxiety and Depression Scale—Deutsche Version (HADS-D); (2.Aufl.)
    1. Wallasch TM, Bek J, Pabel R, Modahl M, Demir M, Straube A. AC-STB - Eine sektorenübergreifende Software zur Dokumentation und Verlaufskontrolle von Kopfschmerzpatienten. Der Schmerz. 2009;2:145–153. doi: 10.1007/s00482-008-0745-6.
    1. Margraf J, Schneider S, Ehlers A (2005) Diagnostisches Interview bei psychischen Störungen (DIPS) (3. Aufl.). Springer, Berlin
    1. Ware J, Jr, Kosinski M, Keller SD. A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. Med Care. 1996;34:220–233. doi: 10.1097/00005650-199603000-00003.
    1. Bullinger M, Kirchberger I (1998) Fragebogen zum Allgemeinen Gesundheitszustand SF12
    1. Maizels M, Smitherman TA, Penzien DB. A review of screening tools for psychiatric comorbidity in headache patients. Headache. 2006;3:98–109. doi: 10.1111/j.1526-4610.2006.00561.x.
    1. Wallasch TM, Hermann C. Validation of criterion-based patient assignment and treatment effectiveness of a multidisciplinary modularized Managed Care Program for Headache. J Headache Pain. 2012;13:379–387. doi: 10.1007/s10194-012-0453-6.
    1. Kabbouche MA, Powers SW, Vockell AL, LeCates SL, Ellinor PL, Segers A, Manning P, Burdine D, Hershey AD. Outcome of a Multidisciplinary Approach to Pediatric Migraine at 1, 2 and 5 years. Headache. 2005;45:1298–1303. doi: 10.1111/j.1526-4610.2005.00261.x.
    1. Hagen K, Stovner LJ. A randomized controlled trial on medication-overuse headache: outcome after 1 and 4 years. Acta Neurol Scand Suppl. 2011;191:38–43. doi: 10.1111/j.1600-0404.2011.01542.x.
    1. Sances G, Ghiotto N, Galli F, Guaschino E, Rezzani C, Guidetti V, Nappi G. Risk factors in medication-overuse headache: a 1-year follow-up study (care II protocol) Cephalalgia. 2010;30(3):329–336.
    1. Ghiotto N, Sances G, Galli F, Tassorelli C, Guaschino E, Sandrini G, Nappi G. Medication overuse headache and applicability of the ICHD-II diagnostic criteria: 1-year follow-up study (CARE I protocol) Cephalalgia. 2009;29(2):233–243. doi: 10.1111/j.1468-2982.2008.01712.x.
    1. Hagen K, Albretsen C, Vilming ST, Salvesen R, Grønning M, Helde G, Gravdahl G, Zwart JA, Stovner LJ. Management of medication overuse headache: 1-year randomized multicentre open-label trial. Cephalalgia. 2009;29(2):221–232. doi: 10.1111/j.1468-2982.2008.01711.x.
    1. Katsarava Z, Muessig M, Dzagnidze A, Fritsche G, Diener HC, Limmroth V. Medication overuse headache: rates and predictors for relapse in a 4-year prospective study. Cephalalgia. 2005;25:12–15. doi: 10.1111/j.1468-2982.2004.00789.x.
    1. Evers S, Marziniak M. Clinical features, pathophysiology, and treatment of medication-overuse headache. Lancet Neurol. 2010;9:391–401. doi: 10.1016/S1474-4422(10)70008-9.
    1. Katsarava Z, Fritsche G, Muessig M, Diener HC, Limmroth V. Clinical feature of withdrawal headache following overuse of triptans and other headache drugs. Neurology. 2001;57:1694–1698. doi: 10.1212/WNL.57.9.1694.
    1. Castillo J, Munoz P, Guitera V, Pascual J. Epidemiology of chronic daily headache in the general population. Headache. 1999;39:190–196. doi: 10.1046/j.1526-4610.1999.3903190.x.
    1. Micieli G, Manzoni GC, Granella F, et al. Clinical and epidemiological observations on drug abuse in headache patients. In: Diener HC, Wilkinson M, et al., editors. Drug-Induced Headache. Berlin: Springer; 1988. pp. 20–28.
    1. Katsarava Z, Limmroth V, Finke M, Diener HC, Fritsche G. Rates and predictors for relapse in medication overuse headache: a 1-year prospective study. Neurology. 2003;60(10):1682–1683. doi: 10.1212/01.WNL.0000063322.14078.90.
    1. Fritsche G, Eberl A, Katsarava Z, Limmroth V, Diener HC. Drug-induced headache: long-term follow up of withrawal therapy and persistence of drug misuse. Eur Neurol. 2001;45:229–235. doi: 10.1159/000052134.
    1. Katsarava Z, Schneeweiss S, Kurth T, Kroener U, Fritsche G, Eikermann A, Diener HC, Limmroth V. Incidence and predictors for chronicity of headache in patients with episodic migraine. Neurology. 2004;62:788–790. doi: 10.1212/01.WNL.0000113747.18760.D2.

Source: PubMed

3
订阅