Osteoarthritis management: Does the pharmacist play a role in bridging the gap between what patients actually know and what they ought to know? Insights from a national online survey

Andrew J McLachlan, Peter R Carroll, David J Hunter, Tom A N Wakefield, Rodney Stosic, Andrew J McLachlan, Peter R Carroll, David J Hunter, Tom A N Wakefield, Rodney Stosic

Abstract

Background: Guidelines encourage engagement in self-care activities for osteoarthritis (OA), but there are gaps in consumers' knowledge about suitable choices for self-care. Community pharmacists are in an ideal position to contribute to OA management through screening and supporting evidence-based pain management choices. Prior research established an association between health literacy and advice-seeking and appropriateness of analgesics choices (both lower in participants with limited health literacy) amongst people living with OA. This article explores the implications of these data for pharmacists in OA management.

Methods: A national online survey was conducted amongst 628 adults aged 45-74 years, currently residing in Australia, with self-reported symptoms of OA. All data were collected using a customized online questionnaire, which was completed only once. 'Self-reported symptoms of OA' was based on six validated screening questions to identify people with OA without a formal clinical diagnosis.

Results: Respondents matched the typical profile of people diagnosed with OA; more than half were female (56%), knees (59%) and hips (31%) were the primary affected joints and 74% were either overweight or obese. Self-identification of OA was limited (41%). Overall, 38% self-managed their pain, and limited health literacy was associated with less advice-seeking. Efficacy and ease of use were the main reasons cited for prompting use across all classes of nonprescription analgesic, with less than 20% reporting recommendation from a pharmacist. Participants were managing their pain with an average of 1.74 (95% confidence interval: 1.60-1.88) analgesics, but 73% reported inadequate pain relief and 54% had disrupted sleep.

Conclusion: Our findings highlight three key themes: lack of self-identification of OA, suboptimal pain relief and limited use of the community pharmacist as a source of management advice. Equipping community pharmacists with tools to identify OA could bridge this gap. More research is needed to determine if it will improve consumers' ability to appropriately manage OA pain.

Patient or public contribution: Consumers living with OA contributed to the study outcomes, reviewed the survey questionnaire for face validity and advised on plain language terminology.

Keywords: Australia; analgesics; community pharmacy; health literacy; osteoarthritis; recommendations; screening.

Conflict of interest statement

All authors have completed the ICMJE uniform disclosure form at www.icmje.org/coi_disclosure.pdf and declare: David J. Hunter reports personal fees and other support from Bayer Australia Ltd., Consumer Healthcare during the conduct of the study and personal fees from Merck Serono, Novartis, Bayer, Tissuegene and TLCBio outside the submitted work. Andrew J. McLachlan reports personal fees and other support from Bayer Australia Ltd., Consumer Healthcare during the conduct of the study and research funding to the Sydney Pharmacy School from GSK to support a PhD scholar under his supervision, outside the submitted work. Peter R. Carroll reports personal fees and other support from Bayer Australia Ltd., Consumer Healthcare during the conduct of the study. Tom A. N. Wakefieldreports receiving personal fees from his employer (Fifty Five 5 Pty., Ltd.), who were paid consulting fees by Bayer Australia Ltd., Consumer Healthcare during the conduct of the study and nonfinancial support provided by Bayer Australia Ltd., Consumer Healthcare during the preparation of the manuscript. Rodney Stosic is an employee of Bayer Australia Ltd. Andrew J. McLachlan (the manuscript's guarantor) affirms that the manuscript is an honest, accurate and transparent account of the study being reported; that no important aspects of the study have been omitted; and that any discrepancies from the study as planned (and, if relevant, registered) have been explained.

© 2022 The Authors. Health Expectations published by John Wiley & Sons Ltd.

Figures

Figure 1
Figure 1
Self‐identification of osteoarthritis (OA) amongst the primary analysis population

References

    1. Safiri S, Kolahi A‐A, Smith E, et al. Global, regional and national burden of osteoarthritis 1990‐2017: a systematic analysis of the Global Burden of Disease Study 2017. Ann Rheum Dis. 2020;79(6):819‐828.
    1. AIHW . Osteoarthritis. Cat. no. PHE 232. Web report. 2019. Accessed July 15, 2021.
    1. Hunter DJ, Bierma‐Zeinstra S. Osteoarthritis. Lancet. 2019;393(10182):1745‐1759.
    1. Royal Australian College of General Practitioners (RACGP). Guideline for the management of knee and hip osteoarthritis, Second Edition. 2018. Accessed July 15, 2021.
    1. Bannuru RR, Osani MC, Vaysbrot EE, et al. OARSI guidelines for the non‐surgical management of knee, hip, and polyarticular osteoarthritis. Osteoarthritis Cartilage. 2019;27(11):1578‐1589.
    1. National Institute for Health and Clinical Excellence . Osteoarthritis: care and management. Clinical Guideline CG177. London: National Institute for Health and Care Excellence (UK). 2014. Accessed July 15, 2021.
    1. March L, Amatya B, Osborne RH, Brand C. Developing a minimum standard of care for treating people with osteoarthritis of the hip and knee. Best Pract Res Clin Rheumatol. 2010;24(1):121‐145.
    1. Kroon FP, van der Burg LR, Buchbinder R, Osborne RH, Johnston RV, Pitt V. Self‐management education programmes for osteoarthritis. Cochrane Database Syst Rev. 2014;(1):Cd008963.
    1. Marks R. Health literacy and osteoarthritis self‐management. J Aging Res Healthcare. 2018;2(3):32‐45.
    1. Adams J, Lowe W, Protheroe J, et al. Self‐management of a musculoskeletal condition for people from harder to reach groups: a qualitative patient interview study. Disabil Rehabil. 2019;41(25):3034‐3042.
    1. Jeon YH, Flaherty I, Urban H, et al. Qualitative evaluation of evidence‐based online decision aid and resources for osteoarthritis management: understanding patient perspectives. Arthritis Care Res. 2019;71(1):46‐55.
    1. Waryasz GR, Gil JA, Kosinski LR, Chiou D, Schiller JR. Patient comprehension of hip arthroscopy: an investigation of health literacy. J Hip Preserv Surg. 2020;7(2):340‐344.
    1. Tsahakis JM, Issar NM, Kadakia RJ, Archer KR, Barzyk T, Mir HR. Health literacy in an orthopaedic trauma patient population: improving patient comprehension with informational intervention. J Orthop Trauma. 2014;28(4):e75‐e79.
    1. Hadden KB, Prince LY, Bushmiaer MK, Watson JC, Barnes CL. Health literacy and surgery expectations in total hip and knee arthroplasty patients. Patient Educ Couns. 2018;101(10):1823‐1827.
    1. Berkman ND, Sheridan SL, Donahue KE, Halpern DJ, Crotty K. Low health literacy and health outcomes: an updated systematic review. Ann Intern Med. 2011;155(2):97‐107.
    1. Schumacher JR, Hall AG, Davis TC, et al. Potentially preventable use of emergency services: the role of low health literacy. Med Care. 2013;51(8):654‐658.
    1. Booker S, Herr K, Tripp‐Reimer T. Patterns and perceptions of self‐management for osteoarthritis pain in African American older adults. Pain Med. 2019;20(8):1489‐1499.
    1. Hunter DJ, McLachlan AJ, Carroll PR, Wakefield TAN, Stosic R. Health literacy and appropriateness of self‐care and pain management in osteoarthritis: an understanding of the patient's perspective. Arthritis Care Res. Published online December 23, 2021. 10.1002/acr.24851
    1. Pouliot A, Vaillancourt R. Medication literacy: why pharmacists should pay attention. Can J Hosp Pharm. 2016;69(4):335‐336.
    1. Carlisle A, Jacobson KL, Di Francesco L, Parker RM. Practical strategies to improve communication with patients. P T. 2011;36(9):576‐589.
    1. Boonstra AM, Stewart RE, Köke AJ, et al. Cut‐off points for mild, moderate, and severe pain on the numeric rating scale for pain in patients with chronic musculoskeletal pain: variability and influence of sex and catastrophizing. Front Psychol. 2016;7:1466.
    1. Hunter DJ, Hinman RS, Bowden JL, et al. Effectiveness of a new model of primary care management on knee pain and function in patients with knee osteoarthritis: protocol for The Partner Study. BMC Musculoskelet Disord. 2018;19(1):132.
    1. Wallace LS, Rogers ES, Roskos SE, Holiday DB, Weiss BD. Brief report: screening items to identify patients with limited health literacy skills. J Gen Intern Med. 2006;21(8):874‐877.
    1. Quinzanos I, Hirsh JM, Bright C, Caplan L. Cross‐sectional correlation of single‐item health literacy screening questions with established measures of health literacy in patients with rheumatoid arthritis. Rheumatol Int. 2015;35(9):1497‐1502.
    1. Finbråten HS, Wilde‐Larsson B, Nordström G, Pettersen KS, Trollvik A, Guttersrud Ø. Establishing the HLS‐Q12 short version of the European Health Literacy Survey Questionnaire: latent trait analyses applying Rasch modelling and confirmatory factor analysis. BMC Health Serv Res. 2018;18(1):506.
    1. Cella D, Choi SW, Condon DM, et al. PROMIS(®) Adult Health Profiles: efficient short‐form measures of seven health domains. Value Health. 2019;22(5):537‐544.
    1. Shim J, Hamilton DF. Comparative responsiveness of the PROMIS‐10 Global Health and EQ‐5D questionnaires in patients undergoing total knee arthroplasty. Bone Joint J. 2019;101‐B(7):832‐837.
    1. Gandek B, Roos EM, Franklin PD, Ware JE, Jr. Item selection for 12‐item short forms of the Knee injury and Osteoarthritis Outcome Score (KOOS‐12) and Hip disability and Osteoarthritis Outcome Score (HOOS‐12). Osteoarthritis Cartilage. 2019;27(5):746‐753.
    1. Gandek B, Roos EM, Franklin PD, Ware JE, Jr. A 12‐item short form of the knee injury and Osteoarthritis Outcome Score (KOOS‐12): tests of reliability, validity and responsiveness. Osteoarthritis Cartilage. 2019;27(5):762‐770.
    1. Gandek B, Roos EM, Franklin PD, Ware JE, Jr. A 12‐item short form of the hip disability and Osteoarthritis Outcome Score (HOOS‐12): tests of reliability, validity and responsiveness. Osteoarthritis Cartilage. 2019;27(5):754‐761.
    1. Dreiser RL, Maheu E, Guillou GB. Sensitivity to change of the functional index for hand osteoarthritis. Osteoarthritis Cartilage. 2000;8(suppl A):S25‐S28.
    1. Dreiser RL, Maheu E, Guillou GB, Caspard H, Grouin JM. Validation of an algofunctional index for osteoarthritis of the hand. Rev Rhum Engl Ed. 1995;62(6 suppl 1):43S‐53S.
    1. Binkley JM, Stratford PW, Lott SA, Riddle DL. The Lower Extremity Functional Scale (LEFS): scale development, measurement properties, and clinical application. North American Orthopaedic Rehabilitation Research Network. Phys Ther. 1999;79(4):371‐383.
    1. Buysse DJ, Reynolds CF, 3rd , Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res. 1989;28(2):193‐213.
    1. Ibáñez V, Silva J, Cauli O. A survey on sleep assessment methods. PeerJ. 2018;6:e4849.
    1. Sangha O, Stucki G, Liang MH, Fossel AH, Katz JN. The self‐administered comorbidity questionnaire: a new method to assess comorbidity for clinical and health services research. Arthritis Care Res. 2003;49(2):156‐163.
    1. Feldman BJ, Fredericksen RJ, Crane PK, et al. Evaluation of the Single‐Item Self‐Rating Adherence Scale for use in routine clinical care of people living with HIV. AIDS Behav. 2013;17(1):307‐318.
    1. Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of a self‐reported measure of medication adherence. Med Care. 1986;24(1):67‐74.
    1. Horne R, Weinman J, Hankins M. The beliefs about medicines questionnaire: the development and evaluation of a new method for assessing the cognitive representation of medication. Psychol Health. 1999;14(1):1‐24.
    1. Brand CA, Harrison C, Tropea J, Hinman RS, Britt H, Bennell K. Management of osteoarthritis in general practice in Australia. Arthritis Care Res. 2014;66(4):551‐558.
    1. Allen KD, Choong PF, Davis AM, et al. Osteoarthritis: models for appropriate care across the disease continuum. Best Pract Res Clin Rheumatol. 2016;30(3):503‐535.
    1. Hunter DJ, Bowden JL. Therapy: are you managing osteoarthritis appropriately? Nat Rev Rheumatol. 2017;13(12):703‐704.
    1. Edwards JJ, Khanna M, Jordan KP, Jordan JL, Bedson J, Dziedzic KS. Quality indicators for the primary care of osteoarthritis: a systematic review. Ann Rheum Dis. 2015;74(3):490‐498.
    1. Guttersrud Ø, Le C, Pettersen KS, Helseth S, Finbråten HS. Towards a progression of health literacy skills: establishing the HLS‐Q12 cutoff scores. Health policy (Amsterdam, Netherlands). 2019.
    1. Kao MH, Tsai YF. Living experiences of middle‐aged adults with early knee osteoarthritis in prediagnostic phase. Disabil Rehabil. 2012;34(21):1827‐1834.
    1. Leopoldino AO, Machado GC, Ferreira PH, et al. Paracetamol versus placebo for knee and hip osteoarthritis. Cochrane Database Syst Rev. 2019;2(2):Cd013273.
    1. Abdel Shaheed C, Ferreira GE, Dmitritchenko A, et al. The efficacy and safety of paracetamol for pain relief: an overview of systematic reviews. Med J Aust. 2021;214(7):324‐331.
    1. Hunter DJ, Bennell K, Austin M, et al. Algorithm—holistic assessment, diagnosis and management of knee and/or hip osteoarthritis. 2018. Accessed July 15, 2021.
    1. Sørensen K, Van den Broucke S, Fullam J, et al. Health literacy and public health: a systematic review and integration of definitions and models. BMC Public Health. 2012;12(1):80.
    1. Sperber NR, Bosworth HB, Coffman CJ, et al. Differences in osteoarthritis self‐management support intervention outcomes according to race and health literacy. Health Educ Res. 2013;28(3):502‐511.
    1. Gignac MA, Davis AM, Hawker G, et al. “What do you expect? You're just getting older”: a comparison of perceived osteoarthritis‐related and aging‐related health experiences in middle‐ and older‐age adults. Arthritis Rheum. 2006;55(6):905‐912.
    1. Bunzli S, O'Brien P, Ayton D, et al. Misconceptions and the acceptance of evidence‐based nonsurgical interventions for knee osteoarthritis. A qualitative study. Clin Orthop Relat Res. 2019;477(9):1975‐1983.
    1. Bowden JL, Lamberts R, Hunter DJ, Melo LR, Mills K. Community‐based online survey on seeking care and information for lower limb pain and injury in Australia: an observational study. BMJ Open. 2020;10(7):e035030.
    1. Kielly J, Davis EM, Marra C. Practice guidelines for pharmacists: the management of osteoarthritis. Can Pharm J. 2017;150(3):156‐168.
    1. Ayorinde AA, Porteous T, Sharma P. Screening for major diseases in community pharmacies: a systematic review. Int J Pharm Pract. 2013;21(6):349‐361.
    1. Downie AS, Hancock M, Abdel Shaheed C, et al. An electronic clinical decision support system for the management of low back pain in community pharmacy: development and mixed methods feasibility study. JMIR Med Inform. 2020;8(5):e17203.
    1. Steed L, Sohanpal R, Todd A, et al. Community pharmacy interventions for health promotion: effects on professional practice and health outcomes. Cochrane Database Syst Rev. 2019;12(12):Cd011207.
    1. Marra CA, Cibere J, Tsuyuki RT, et al. Improving osteoarthritis detection in the community: pharmacist identification of new, diagnostically confirmed osteoarthritis. Arthritis Rheum. 2007;57(7):1238‐1244.
    1. Kairuz TE, Bellamy KM, Lord E, Ostini R, Emmerton LM. Health literacy among consumers in community pharmacy: perceptions of pharmacy staff. Health Expect. 2015;18(5):1041‐1051.

Source: PubMed

3
订阅