Long-term risks after kidney donation: how do we inform potential donors? A survey from DESCARTES and EKITA transplantation working groups

Geir Mjøen, Umberto Maggiore, Nicos Kessaris, Diederik Kimenai, Bruno Watschinger, Cristophe Mariat, Mehmet Sukru Sever, Marta Crespo, Licia Peruzzi, Goce Spasovski, Søren Schwartz Sørensen, Uwe Heemann, Julio Pascual, Ondrej Viklicky, Aisling E Courtney, Karine Hadaya, Laszlo Wagner, Ionut Nistor, Vassilis Hadjianastassiou, Magdalena Durlik, Ilkka Helanterä, Rainer Oberbauer, Gabriel Oniscu, Luuk Hilbrands, Daniel Abramowicz, Geir Mjøen, Umberto Maggiore, Nicos Kessaris, Diederik Kimenai, Bruno Watschinger, Cristophe Mariat, Mehmet Sukru Sever, Marta Crespo, Licia Peruzzi, Goce Spasovski, Søren Schwartz Sørensen, Uwe Heemann, Julio Pascual, Ondrej Viklicky, Aisling E Courtney, Karine Hadaya, Laszlo Wagner, Ionut Nistor, Vassilis Hadjianastassiou, Magdalena Durlik, Ilkka Helanterä, Rainer Oberbauer, Gabriel Oniscu, Luuk Hilbrands, Daniel Abramowicz

Abstract

Background: Publications from the last decade have increased knowledge regarding long-term risks after kidney donation. We wanted to perform a survey to assess how transplant professionals in Europe inform potential kidney donors regarding long-term risks. The objectives of the survey were to determine how they inform donors and to what extent, and to evaluate the degree of variation.

Methods: All transplant professionals involved in the evaluation process were considered eligible, regardless of the type of profession. The survey was dispatched as a link to a web-based survey. The subjects included questions on demographics, the information policy of the respondent and the use of risk calculators, including the difference of relative and absolute risks and how the respondents themselves understood these risks.

Results: The main finding was a large variation in how often different long-term risks were discussed with the potential donors, i.e. from always to never. Eighty percent of respondents stated that they always discuss the risk of end-stage renal disease, while 56% of respondents stated that they always discuss the risk of preeclampsia. Twenty percent of respondents answered correctly regarding the relationship between absolute and relative risks for rare outcomes.

Conclusions: The use of written information and checklists should be encouraged. This may improve standardization regarding the information provided to potential living kidney donors in Europe. There is a need for information and education among European transplant professionals regarding long-term risks after kidney donation and how to interpret and present these risks.

Keywords: kidney donors; long-term risks; transplant professionals.

© The Author(s) 2021. Published by Oxford University Press on behalf of ERA-EDTA.

Figures

FIGURE 1
FIGURE 1
Origin of the respondents to the survey, reported as proportion of the total (A) and as number of respondents per 10 living donor kidney transplants in their own country (B). The number of living donor kidney transplants was based on data from the Global Observatory on Donation and Transplantation for the year 2018 (http://www.transplant-observatory.org/); in (B), countries with ˂20 living donor kidney transplants in 2018 are reported in grey. Colour scale (legend on the right) reflects the numbers in the plot.
FIGURE 2
FIGURE 2
Findings from Table 2 are reported as stacked bar chart to facilitate the comparison across the different survey items.
FIGURE 3
FIGURE 3
Findings from Table 3 are reported as stacked bar chart to facilitate the comparison across the different survey items. AR, absolute risk; RR, relative risk.

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Source: PubMed

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