Crossover clinical trial of pain relief in cataract surgery

Suvin Choi, Sang-Gue Park, Lorne Bellan, Hyung-Hwan Lee, Sung Kun Chung, Suvin Choi, Sang-Gue Park, Lorne Bellan, Hyung-Hwan Lee, Sung Kun Chung

Abstract

Purpose: To determine the effects of intra-operative Korean traditional music on pain experienced by Korean patients undergoing sequential bilateral cataract surgery.

Methods: This was a two-sequence, two-period, and two-treatment crossover study. Fifty-two patients with cataracts were divided into two groups by block randomization, and bilateral cataract surgery was performed. In group 1, patients listened to Korean traditional music (KTM) during their first but not second cataract surgery. This sequence was reversed for patients in group 2. After each surgery, patients scored their pain intensity (PI) using a visual analog scale (VAS) ranging from 0 to 10, where 0 was 'no pain' and 10 was 'unbearable pain.'

Result: There was a statistically significant reduction in the mean VAS score with KTM (3.1 ± 2.0) compared to that without KTM (4.1 ± 2.2; p = 0.013). However, there were no statistically significant differences in blood pressure or pulse rates.

Conclusion: KTM had a significant effect on reducing pain experienced by patients during cataract surgery. This may be useful in the context of other surgical procedures to reduce pain in Korean patients.

Keywords: Adjuvant therapy; Cataract surgery; Crossover design; Pain; Washout period.

Conflict of interest statement

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in this study.

Figures

Fig. 1
Fig. 1
Two-sequence, two-period, and two-treatment crossover design

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Source: PubMed

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