Correlation of Vitamin D status and orthodontic-induced external apical root resorption

Azita Tehranchi, Azin Sadighnia, Farnaz Younessian, Amir H Abdi, Armin Shirvani, Azita Tehranchi, Azin Sadighnia, Farnaz Younessian, Amir H Abdi, Armin Shirvani

Abstract

Background: Adequate Vitamin D is essential for dental and skeletal health in children and adult. The purpose of this study was to assess the correlation of serum Vitamin D level with external-induced apical root resorption (EARR) following fixed orthodontic treatment.

Materials and methods: In this cross-sectional study, the prevalence of Vitamin D deficiency (defined by25-hydroxyvitamin-D) was determined in 34 patients (23.5% male; age range 12-23 years; mean age 16.63 ± 2.84) treated with fixed orthodontic treatment. Root resorption of four maxillary incisors was measured using before and after periapical radiographs (136 measured teeth) by means of a design-to-purpose software to optimize data collection. Teeth with a maximum percentage of root resorption (%EARR) were indicated as representative root resorption for each patient. A multiple linear regression model and Pearson correlation coefficient were used to assess the association of Vitamin D status and observed EARR. P < 0.05 was considered statistically significant.

Results: The Pearson coefficient between these two variables was determined about 0.15 (P = 0.38). Regression analysis revealed that Vitamin D status of the patients demonstrated no significant statistical correlation with EARR, after adjustment of confounding variables using linear regression model (P > 0.05).

Conclusion: This study suggests that Vitamin D level is not among the clinical variables that are potential contributors for EARR. The prevalence of Vitamin D deficiency does not differ in patients with higher EARR. These data suggest the possibility that Vitamin D insufficiency may not contribute to the development of more apical root resorption although this remains to be confirmed by further longitudinal cohort studies.

Keywords: 25-Hydroxycalciferol; Vitamin D; orthodontics; root resorption.

Conflict of interest statement

The authors of this manuscript declare that they have no conflicts of interest, real or perceived, financial or non-financial in this article.

Figures

Figure 1
Figure 1
Evaluation method of external apical root resorption. (a) Point selection of a sample incisor teeth, at the start of the treatment (left), (b) point selection of the same sample at the end of the fixed orthodontic treatment (right).

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Source: PubMed

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