Effects of poor and short sleep on glucose metabolism and obesity risk
Karine Spiegel, Esra Tasali, Rachel Leproult, Eve Van Cauter, Karine Spiegel, Esra Tasali, Rachel Leproult, Eve Van Cauter
Abstract
The importance of sleep to hormones and glucose metabolism was first documented more than four decades ago. Since then, sleep curtailment has become an endemic behavior in modern society. In addition, the prevalence of sleep disorders, particularly obstructive sleep apnea (OSA), has increased. OSA is very common in endocrine and metabolic disorders, but often remains undiagnosed. This Review summarizes the laboratory and epidemiologic evidence that suggests how sleep loss, either behavioral or disease-related, and poor quality of sleep might promote the development of obesity and diabetes mellitus, and exacerbate existing endocrine conditions. Treatment of sleep disorders has the potential to improve glucose metabolism and energy balance. Screening for habitual sleep patterns and OSA might be critically important for patients with endocrine and metabolic disorders.
Conflict of interest statement
Competing Interests
E. Van Cauter has declared associations with the following companies: Actelyon and Sanofi-Aventis. See the article online for full details of the relationships. R. Leprout, K. Spiegel and E. Tasali declared no competing interests.
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Source: PubMed