Ultrasound-guided percutaneous needle electrolysis in chronic lateral epicondylitis: short-term and long-term results

Fermín Valera-Garrido, Francisco Minaya-Muñoz, Francesc Medina-Mirapeix, Fermín Valera-Garrido, Francisco Minaya-Muñoz, Francesc Medina-Mirapeix

Abstract

Background: Ultrasound (US)-guided percutaneous needle electrolysis (PNE) is a novel minimally invasive approach which consists of the application of a galvanic current through an acupuncture needle.

Objective: To evaluate the clinical and ultrasonographic effectiveness of a multimodal programme (PNE, eccentric exercise (EccEx) and stretching) in the short term for patients with chronic lateral epicondylitis, and to determine whether the clinical outcomes achieved decline over time.

Methods: A one-way repeated measures study was performed in a clinical setting in 36 patients presenting with lateral epicondylitis. The patients received one session of US-guided PNE per week over 4-6 weeks, associated with a home programme of EccEx and stretching. The main outcome measures were severity of pain, disability (Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire), structural tendon changes (US), hypervascularity and patients' perceptions of overall outcome. Measurements at 6, 26 and 52 weeks follow-up included recurrence rates (increase in severity of pain or disability compared with discharge), perception of overall outcome and success rates.

Results: All outcome measures registered significant improvements between pre-intervention and discharge. Most patients (n=30, 83.3%) rated the overall outcome as 'successful' at 6 weeks. The ultrasonographic findings showed that the hypoechoic regions and hypervascularity of the extensor carpi radialis brevis changed significantly. At 26 and 52 weeks, all participants (n=32) perceived a 'successful' outcome. Recurrence rates were null after discharge and at follow-up at 6, 26 and 52 weeks.

Conclusions: Symptoms and degenerative structural changes of chronic lateral epicondylitis are reduced after US-guided PNE associated with EccEx and stretching, with encouragingly low recurrences in the mid to long term.

Trial registration number: ClinicalTrials.gov identifier: NCT02085928.

Keywords: SPORTS MEDICINE; ULTRASONOGRAPHY.

Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Figures

Figure 1
Figure 1
(A) Long-axis grey-scale ultrasound image displaying the origin of the extensor tendon during needle placement showing the echogenic needle (arrowheads) with the distal tip in the area of tendinosis. (B–D) Percutaneous needle electrolysis was performed with continual sonographic guidance. A white area is observed in the tissue approximately 30 min post-intervention. LE, lateral epicondyle.
Figure 2
Figure 2
Detail of cathode (modified electrosurgical scalpel with the needle) and anode (handheld electrode) electrodes for percutaneous needle electrolysis.
Figure 3
Figure 3
Needle approach. (A) In-plane approach. The transducer is placed on the lateral epicondyle and the needle is inserted in the centre of the transducer in a long axis position at an angle of about 30–45° to the skin surface, depending on the target area, and then advanced parallel to the sound beam. (B) Out-of-plane approach. The transducer is placed over the humeroradial joint and the needle is positioned at the centre of the transducer in a short axis position at an angle of about 80° to the skin surface and advanced perpendicular to the sound beam. LE, lateral epicondyle; RH, radial head; yellow line, lateral ulnar collateral ligament; blue line, capsule of the humeroradial joint; pink structure, common extensor tendon.
Figure 4
Figure 4
Lateral epicondylitis in a patient with a history of chronic right lateral elbow pain. (A) At baseline, long-axis grey-scale ultrasound (US) image reveals an irregular structure and a hypoechoic focus (asterisks) in the deep fibres of the extensor carpi radialis brevis. (B) At 6 weeks follow-up, US image of the same patient shows structural changes inside the initial area (arrowheads). (C) Power Doppler imaging demonstrates a striking hypervascular pattern composed of a series of tiny vessels. (D) Power Doppler imaging shows no blood flow inside the initial area. LE, lateral epicondyle; RH, radial head.

References

    1. Shiri R, Viikari-Juntura E, Varonen H, et al. Prevalence and determinants of lateral and medial epicondylitis: a population study. Am J Epidemiol 2006;164:1065–74.
    1. Verhaar JA. Tennis elbow. Anatomical, epidemiological and therapeutic aspects. Int Orthop 1994;18:263–7.
    1. Faro F, Wolf JM. Lateral epicondylitis: review and current concepts. J Hand Surg [Am] 2007;32:1271–9.
    1. Scher D, Wolf J. Lateral epicondylitis. Orthopedics 2009;32:276–82.
    1. Smidt N, Lewis M, Van Der Windt DA, et al. Lateral epicondylitis in general practice: course and prognostic indicators of outcome. J Rheumatol 2006;33:2053–9.
    1. Cummins CA. Lateral epicondylitis: in vivo assessment of arthroscopic debridement and correlation with patient outcomes. Am J Sports Med 2006;34:1486–91.
    1. Solheim E, Hegna J, Oyen J. Arthroscopic versus open tennis elbow release: 3- to 6-year results of a case-control series of 305 elbows. Arthroscopy 2013;29:854–9.
    1. Cyriax JH. The pathology and treatment of tennis elbow. J Bone Joint Surg Am 1936;18:921–40.
    1. Krogh TP, Bartels EM, Ellingsen T, et al. Comparative effectiveness of injection therapies in lateral epicondylitis: a systematic review and network meta-analysis of randomized controlled trials. Am J Sports Med 2013;41:1435–46.
    1. Bisset L, Beller E, Jull G, et al. Mobilisation with movement and exercise, corticosteroid injection, or wait and see for tennis elbow: randomised trial. BMJ 2006;333:939.
    1. Coombes BK, Bisset L, Brooks P, et al. Effect of corticosteroid injection, physiotherapy, or both on clinical outcomes in patients with unilateral lateral epicondylalgia: a randomized controlled trial. JAMA 2013;309:461–9.
    1. Zeisig E, Fahlström M, Ohberg L, et al. A two-year sonographic follow-up after intratendinous injection therapy in patients with tennis elbow. Br J Sports Med 2010;44:584–7.
    1. Cook JL, Purdam CR. Is tendon pathology a continuum? A pathology model to explain the clinical presentation of load induced tendinopathy. Br J Sports Med 2009;43:409–16.
    1. Nirschl RP. Elbow tendinosis/tennis elbow. Clin Sports Med 1992;11:851–70.
    1. Regan W, Wold LE, Coonrad R, et al. Microscopic histopathology of chronic refractory lateral epicondylitis. Am J Sports Med 1992;20:746–9.
    1. Zeisig E, Öhberg L, Alfredson H. Extensor origin vascularity related to pain in patients with tennis elbow. Knee Surg Sports Traumatol Arthrosc 2006;14:659–63.
    1. Alfredson H, Ljung BO, Thorsen K, et al. In vivo investigation of ECRB tendons with microdialysis technique—no signs of inflammation but high amounts of glutamate in tennis elbow. Acta Orthop Scand 2000;71:475–9.
    1. Fredberg U, Stengaard-Pedersen K. Chronic tendinopathy tissue pathology, pain mechanisms, and etiology with a special focus on inflammation. Scand J Med Sci Sports 2008;18:3–15.
    1. Bales CP, Placzek JD, Malone KJ, et al. Microvascular supply of the lateral epicondyle and common extensor origin. J Shoulder Elbow Surg 2007;16:497–501.
    1. Walz DM, Newman JS, Konin GP, et al. Epicondylitis: pathogenesis, imaging, and treatment. Radiographics 2010;30:167–84.
    1. Mishra A, Pavelko T. Treatment of chronic elbow tendinosis with buffered platelet-rich plasma. Am J Sports Med 2006;34:1774–8.
    1. Lin CL, Lee JS, Su WR, et al. Clinical and ultrasonographic results of ultrasonographically guided percutaneous radiofrequency lesioning in the treatment of recalcitrant lateral epicondylitis. Am J Sports Med 2011;39:2429–35.
    1. Finnoff JT, Fowler SP, Lai JK, et al. Treatment of chronic tendinopathy with ultrasound-guided needle tenotomy and platelet-rich plasma injection. PM R 2011;3:900–11.
    1. Housner JA, Jacobson JA, Misko R. Sonographically guided percutaneous needle tenotomy for the treatment of chronic tendinosis. J Ultrasound Med 2009;28:1187–92.
    1. Settergren R. Treatment of supraspinatus tendinopathy with ultrasound guided dry needling. J Chiropr Med 2013;12:26–9.
    1. Nagraba Ł, Tuchalska J, Mitek T, et al. Dry needling as a method of tendinopathy treatment. Ortop Traumatol Rehabil 2013;15:109–16.
    1. Almeida Mdos S, Guerra Fda R, de Oliveira LP, et al. A hypothesis for the anti-inflammatory and mechanotransduction molecular mechanisms underlying acupuncture tendon healing. Acupunct Med 2014;32: 178–82.
    1. Valera-Garrido F, Minaya-Muñoz F, Sánchez-Ibáñez JM. Efectividad de la electrólisis percutánea intratisular (EPI®) en las tendinopatías crónicas del tendón rotuliano. Trauma Fund MAPFRE 2010;21:227–36.
    1. Valera-Garrido F, Minaya-Muñoz F. Fisioterapia invasiva. Barcelona: Elsevier, 2013.
    1. Valera-Garrido F, Minaya-Muñoz F, Sánchez-Ibáñez JM, et al. Comparison of the acute inflammatory response and proliferation of dry needling and electrolysis percutaneous intratissue (EPI) in healthy rat Achilles tendons. Br J Sports Med 2013;47:e2.
    1. Malliaras P, Maffulli N, Garau G. Eccentric training programmes in the management of lateral elbow tendinopathy. Disabil Rehabil 2008;30:1590–6.
    1. Stasinopoulos D, Stasinopoulou K, Stasinopoulos I, et al. Comparison of effects of a home exercise programme and a supervised exercise programme for the management of lateral elbow tendinopathy. Br J Sports Med 2010;44:579–83.
    1. Martinez-Silvestrini JA, Newcomer KL, Gay RE, et al. Chronic lateral epicondylitis: comparative effectiveness of a home exercise program including stretching alone versus stretching supplemented with eccentric or concentric strengthening. J Hand Ther 2005;18:411–19.
    1. Takasaki H, Aoki M, Muraki T, et al. Muscle strain on the radial wrist extensors during motion-simulating stretching exercises for lateral epicondylitis: a cadaveric study. J Shoulder Elbow Surg 2007;16:854–8.
    1. Hervás M, Navarro Collado MJ, Peiró S, et al. Versión española del cuestionario DASH. Adaptación transcultural, fiabilidad, validez y sensibilidad a los cambios. Med Clin (Barc) 2006;127:441–7.
    1. Beggs I, Bianchi S, Bueno A, et al. ESSR Ultrasound Group Protocols. Musculoskeletal Ultrasound Technical Guidelines: Knee. (accessed 2 Aug 2013).
    1. Coombes BK, Bisset L, Connelly LB, et al. Optimising corticosteroid injection for lateral epicondylalgia with the addition of physiotherapy: a protocol for a randomised control trial with placebo comparison. BMC Musculoskelet Disord 2009;10:76.
    1. Drew BT, Smith TO, Littlewood C, et al. Do structural changes (eg, collagen/matrix) explain the response to therapeutic exercises in tendinopathy: a systematic review. Br J Sports Med 2014;48:966–72.
    1. James SL, Ali K, Pocock C, et al. Ultrasound guided dry needling and autologous blood injection for patellar tendinosis. Br J Sports Med 2007;41:518–21 discussion 522.
    1. Rha DW, Park GY, Kim YK, et al. Comparison of the therapeutic effects of ultrasound-guided platelet-rich plasma injection and dry needling in rotator cuff disease: a randomized controlled trial. Clin Rehabil 2013;27:113–22.
    1. Virchenko O, Aspenberg P. How can one platelet injection after tendon injury lead to a stronger tendon after 4 weeks? Interplay between early regeneration and mechanical stimulation. Acta Orthop 2006;77:806–12.
    1. Croisier JL, Foidart-Dessalle M, Tinant F, et al. An isokinetic eccentric programme for the management of chronic lateral epicondylar tendinopathy. Br J Sports Med 2007;41: 269–75.
    1. Minaya-Muñoz F, Valera-Garrido F, Sánchez-Ibáñez JM. Uso de la electrólisis percutánea intratisular (EPI®) en la epicondilagia crónica: caso clínico. Fisioter calid vida 2011;14: 13–16.
    1. Thanasas C, Papadimitriou G, Charalambidis C, et al. Platelet-rich plasma versus autologous whole blood for the treatment of chronic lateral elbow epicondylitis: a randomized controlled clinical trial. Am J Sports Med 2011;39:2130–4.
    1. Struijs PA, Kerkhoffs GM, Assendelft WJ, et al. Conservative treatment of lateral epicondylitis: brace versus physical therapy or a combination of both-a randomized clinical trial. Am J Sports Med 2004;32:462–9.

Source: PubMed

3
订阅