Laparoscopic appendectomy for acute appendicitis: How to discourage surgeons using inadequate therapy

Tomohide Hori, Takafumi Machimoto, Yoshio Kadokawa, Toshiyuki Hata, Tatsuo Ito, Shigeru Kato, Daiki Yasukawa, Yuki Aisu, Yusuke Kimura, Maho Sasaki, Yuichi Takamatsu, Taku Kitano, Shigeo Hisamori, Tsunehiro Yoshimura, Tomohide Hori, Takafumi Machimoto, Yoshio Kadokawa, Toshiyuki Hata, Tatsuo Ito, Shigeru Kato, Daiki Yasukawa, Yuki Aisu, Yusuke Kimura, Maho Sasaki, Yuichi Takamatsu, Taku Kitano, Shigeo Hisamori, Tsunehiro Yoshimura

Abstract

Acute appendicitis (AA) develops in a progressive and irreversible manner, even if the clinical course of AA can be temporarily modified by intentional medications. Reliable and real-time diagnosis of AA can be made based on findings of the white blood cell count and enhanced computed tomography. Emergent laparoscopic appendectomy (LA) is considered as the first therapeutic choice for AA. Interval/delayed appendectomy at 6-12 wk after disease onset is considered as unsafe with a high recurrent rate during the waiting time. However, this technique may have some advantages for avoiding unnecessary extended resection in patients with an appendiceal mass. Non-operative management of AA may be tolerated only in children. Postoperative complications increase according to the patient's factors, and temporal avoidance of emergent general anesthesia may be beneficial for high-risk patients. The surgeon's skill and cooperation of the hospital are important for successful LA. Delaying appendectomy for less than 24 h from diagnosis is safe. Additionally, a semi-elective manner (i.e., LA within 24 h after onset of symptoms) may be paradoxically acceptable, according to the factors of the patient, physician, and institution. Prompt LA is mandatory for AA. Fortunately, the Japanese government uses a universal health insurance system, which covers LA.

Keywords: Acute appendicitis; Delayed appendectomy; Interval appendectomy; Laparoscopic appendectomy; Surgery.

Conflict of interest statement

Conflict-of-interest statement: No potential conflicts of interest.

Figures

Figure 1
Figure 1
Port placement and laparoscopic view. A-C: If the left lateral port is set for laparoscope, a wider angle of working forceps can be made. However, a stab scar of 5 mm remains visible; D-F: Port placements for LA using an endostaple with the best cosmesis are shown. LA: Laparoscopic appendectomy.
Figure 2
Figure 2
Major techniques during laparoscopic appendectomy. A: A suprapubic port (5 mm) for a flexible laparoscope is placed within the area of pubic hair (dotted blue line) to hide the postoperative stab scar. A left lateral port (3 mm) is placed as low as possible, to enable an adequate angle for the working forceps and to hide the postoperative stab scar by underwear; B: The bladder wall (red arrows), the dome of the bladder (dotted blue line), and the central umbilical fold should be recognized. Although the suprapubic peritoneum easily extends during port insertion, a suprapubic port should be placed without bladder injury; C: Any injury of the left inferior epigastric vessels should be avoided; D: Countertraction of the mesoappendix (red arrow) should be made without obstruction of the abdominal wall. Gripping and rotating forces of 3-mm forceps are sufficient. The appendix can be shortened in a rolled-in fashion (blue arrow) to avoid any disturbance by the abdominal wall.
Figure 3
Figure 3
Key techniques during laparoscopic appendectomy. A: Appendiceal vessels should be clearly dissected and be sealed without a clip for subsequent use of an endostaple; B: Total resection of the appendiceal root should be made (red solid arrow). A flexible endostaple has an advantage in extended resection to the cecum (red dotted arrow); C: The ileocecal valve should be recognized before an endostaple is placed (red arrow). Any involvement of this valve should be avoided; D: The externally-inverted staple line should be carefully checked. If there is any concern about a stump, a couple of interrupted seromuscular sutures can be added. Unrelated and spilled staples (blue arrow) should be removed.

References

    1. Stewart D. The management of acute appendicitis. In: Cameron JL, Cameron AM, editors. Current surgical therapy. Philadelphia: Elsevier Saunders; 2014: 252-255 In: Cameron JL, Cameron AM, editors.
    1. Quartey B. Interval appendectomy in adults: A necessary evil? J Emerg Trauma Shock. 2012;5:213–216.
    1. Ditillo MF, Dziura JD, Rabinovici R. Is it safe to delay appendectomy in adults with acute appendicitis? Ann Surg. 2006;244:656–660.
    1. Udgiri N, Curras E, Kella VK, Nagpal K, Cosgrove J. Appendicitis, is it an emergency? Am Surg. 2011;77:898–901.
    1. Cervini P, Smith LC, Urbach DR. The surgeon on call is a strong factor determining the use of a laparoscopic approach for appendectomy. Surg Endosc. 2002;16:1774–1777.
    1. Sicard N, Tousignant P, Pineault R, Dubé S. Non-patient factors related to rates of ruptured appendicitis. Br J Surg. 2007;94:214–221.
    1. Eldar S, Nash E, Sabo E, Matter I, Kunin J, Mogilner JG, Abrahamson J. Delay of surgery in acute appendicitis. Am J Surg. 1997;173:194–198.
    1. Langelotz C, Scharfenberg M, Haase O, Schwenk W. Stress and heart rate variability in surgeons during a 24-hour shift. Arch Surg. 2008;143:751–755.
    1. Kelz RR, Freeman KM, Hosokawa PW, Asch DA, Spitz FR, Moskowitz M, Henderson WG, Mitchell ME, Itani KM. Time of day is associated with postoperative morbidity: an analysis of the national surgical quality improvement program data. Ann Surg. 2008;247:544–552.
    1. Zare MM, Itani KM, Schifftner TL, Henderson WG, Khuri SF. Mortality after nonemergent major surgery performed on Friday versus Monday through Wednesday. Ann Surg. 2007;246:866–874.
    1. Skoubo-Kristensen E, Hvid I. The appendiceal mass: results of conservative management. Ann Surg. 1982;196:584–587.
    1. Hoffmann J, Lindhard A, Jensen HE. Appendix mass: conservative management without interval appendectomy. Am J Surg. 1984;148:379–382.
    1. Adalla SA. Appendiceal mass: interval appendicectomy should not be the rule. Br J Clin Pract. 1996;50:168–169.
    1. Lai HW, Loong CC, Chiu JH, Chau GY, Wu CW, Lui WY. Interval appendectomy after conservative treatment of an appendiceal mass. World J Surg. 2006;30:352–357.
    1. Vons C, Barry C, Maitre S, Pautrat K, Leconte M, Costaglioli B, Karoui M, Alves A, Dousset B, Valleur P, et al. Amoxicillin plus clavulanic acid versus appendicectomy for treatment of acute uncomplicated appendicitis: an open-label, non-inferiority, randomised controlled trial. Lancet. 2011;377:1573–1579.
    1. Nitecki S, Assalia A, Schein M. Contemporary management of the appendiceal mass. Br J Surg. 1993;80:18–20.
    1. Andersson RE, Petzold MG. Nonsurgical treatment of appendiceal abscess or phlegmon: a systematic review and meta-analysis. Ann Surg. 2007;246:741–748.
    1. Mason RJ. Appendicitis: is surgery the best option? Lancet. 2011;377:1545–1546.
    1. Arnbjörnsson E. Acute appendicitis and dietary fiber. Arch Surg. 1983;118:868–870.
    1. Andersson N, Griffiths H, Murphy J, Roll J, Serenyi A, Swann I, Cockcroft A, Myers J, St Leger A. Is appendicitis familial? Br Med J. 1979;2:697–698.
    1. Jones BA, Demetriades D, Segal I, Burkitt DP. The prevalence of appendiceal fecaliths in patients with and without appendicitis. A comparative study from Canada and South Africa. Ann Surg. 1985;202:80–82.
    1. Larner AJ. The aetiology of appendicitis. Br J Hosp Med. 1988;39:540–542.
    1. Canterino JE, McCormack M, Gurung A, Passarelli J, Landry ML, Golden M. Cytomegalovirus appendicitis in an immunocompetent host. J Clin Virol. 2016;78:9–11.
    1. Plataras C, Tsangouri S, Bourikas D, Christianakis E. Acute appendicitis in a child with swine influenza (H1N1) BMJ Case Rep. 2015;2015:pii: bcr2014208219.
    1. Cheluvappa R, Luo AS, Palmer C, Grimm MC. Protective pathways against colitis mediated by appendicitis and appendectomy. Clin Exp Immunol. 2011;165:393–400.
    1. Kokkonen TS, Karttunen TJ. Endothelial Fas-Ligand in Inflammatory Bowel Diseases and in Acute Appendicitis. J Histochem Cytochem. 2015;63:931–942.
    1. Bockman DE. Functional histology of appendix. Arch Histol Jpn. 1983;46:271–292.
    1. Di Sebastiano P, Fink T, di Mola FF, Weihe E, Innocenti P, Friess H, Büchler MW. Neuroimmune appendicitis. Lancet. 1999;354:461–466.
    1. Wang Y, Reen DJ, Puri P. Is a histologically normal appendix following emergency appendicectomy alway normal? Lancet. 1996;347:1076–1079.
    1. de Oliveira Machado SL, Bagatini MD, da Costa P, Baldissarelli J, Reichert KP, de Oliveira LS, Lemos JG, Duarte T, Chitolina Schetinger MR, Morsch VM. Evaluation of mediators of oxidative stress and inflammation in patients with acute appendicitis. Biomarkers. 2016;21:530–537.
    1. Rivera-Chavez FA, Peters-Hybki DL, Barber RC, Lindberg GM, Jialal I, Munford RS, O’Keefe GE. Innate immunity genes influence the severity of acute appendicitis. Ann Surg. 2004;240:269–277.
    1. Khalil M, Rhee P, Jokar TO, Kulvatunyou N, O’Keeffe T, Tang A, Hassan A, Gries L, Latifi R, Joseph B. Antibiotics for appendicitis! Not so fast. J Trauma Acute Care Surg. 2016;80:923–932.
    1. Wagner JM, McKinney WP, Carpenter JL. Does this patient have appendicitis? JAMA. 1996;276:1589–1594.
    1. Lukáš K. [The story of Appendix] Cas Lek Cesk. 2015;154:189–193.
    1. Arnbjörnsson E. Management of appendiceal abscess. Curr Surg. 1984;41:4–9.
    1. Chen KC, Arad A, Chen KC, Storrar J, Christy AG. The clinical value of pathology tests and imaging study in the diagnosis of acute appendicitis. Postgrad Med J. 2016;92:611–619.
    1. Kim HC, Yang DM, Kim SW, Park SJ. Reassessment of CT images to improve diagnostic accuracy in patients with suspected acute appendicitis and an equivocal preoperative CT interpretation. Eur Radiol. 2012;22:1178–1185.
    1. Hopkins JA, Wilson SE, Bobey DG. Adjunctive antimicrobial therapy for complicated appendicitis: bacterial overkill by combination therapy. World J Surg. 1994;18:933–938.
    1. Rao PM, Rhea JT, Novelline RA, Mostafavi AA, McCabe CJ. Effect of computed tomography of the appendix on treatment of patients and use of hospital resources. N Engl J Med. 1998;338:141–146.
    1. Wagner PL, Eachempati SR, Soe K, Pieracci FM, Shou J, Barie PS. Defining the current negative appendectomy rate: for whom is preoperative computed tomography making an impact? Surgery. 2008;144:276–282.
    1. Pritchett CV, Levinsky NC, Ha YP, Dembe AE, Steinberg SM. Management of acute appendicitis: the impact of CT scanning on the bottom line. J Am Coll Surg. 2010;210:699–705, 705-707.
    1. Livingston EH, Woodward WA, Sarosi GA, Haley RW. Disconnect between incidence of nonperforated and perforated appendicitis: implications for pathophysiology and management. Ann Surg. 2007;245:886–892.
    1. Aly NE, McAteer D, Aly EH. Low vs. standard dose computed tomography in suspected acute appendicitis: Is it time for a change? Int J Surg. 2016;31:71–79.
    1. Zviedre A, Engelis A, Tretjakovs P, Jurka A, Zile I, Petersons A. Role of serum cytokines in acute appendicitis and acute mesenteric lymphadenitis among children. Medicina (Kaunas) 2016;52:291–297.
    1. Sack U, Biereder B, Elouahidi T, Bauer K, Keller T, Tröbs RB. Diagnostic value of blood inflammatory markers for detection of acute appendicitis in children. BMC Surg. 2006;6:15.
    1. Sülberg D, Chromik AM, Kersting S, Meurer K, Tannapfel A, Uhl W, Mittelkötter U. [Appendicitis in the elderly. CRP value as decision support for diagnostic laparoscopy] Chirurg. 2009;80:608–614.
    1. Jeon BG. Predictive factors and outcomes of negative appendectomy. Am J Surg. 2017;213:731–738.
    1. Kabir SA, Kabir SI, Sun R, Jafferbhoy S, Karim A. How to diagnose an acutely inflamed appendix; a systematic review of the latest evidence. Int J Surg. 2017;40:155–162.
    1. Semm K. Endoscopic appendectomy. Endoscopy. 1983;15:59–64.
    1. Heinzelmann M, Simmen HP, Cummins AS, Largiadèr F. Is laparoscopic appendectomy the new ‘gold standard’? Arch Surg. 1995;130:782–785.
    1. Chung RS, Rowland DY, Li P, Diaz J. A meta-analysis of randomized controlled trials of laparoscopic versus conventional appendectomy. Am J Surg. 1999;177:250–256.
    1. Garbutt JM, Soper NJ, Shannon WD, Botero A, Littenberg B. Meta-analysis of randomized controlled trials comparing laparoscopic and open appendectomy. Surg Laparosc Endosc. 1999;9:17–26.
    1. Golub R, Siddiqui F, Pohl D. Laparoscopic versus open appendectomy: a metaanalysis. J Am Coll Surg. 1998;186:545–553.
    1. Sauerland S, Lefering R, Holthausen U, Neugebauer EA. Laparoscopic vs conventional appendectomy--a meta-analysis of randomised controlled trials. Langenbecks Arch Surg. 1998;383:289–295.
    1. Temple LK, Litwin DE, McLeod RS. A meta-analysis of laparoscopic versus open appendectomy in patients suspected of having acute appendicitis. Can J Surg. 1999;42:377–383.
    1. Faiz O, Clark J, Brown T, Bottle A, Antoniou A, Farrands P, Darzi A, Aylin P. Traditional and laparoscopic appendectomy in adults: outcomes in English NHS hospitals between 1996 and 2006. Ann Surg. 2008;248:800–806.
    1. Fullum TM, Ladapo JA, Borah BJ, Gunnarsson CL. Comparison of the clinical and economic outcomes between open and minimally invasive appendectomy and colectomy: evidence from a large commercial payer database. Surg Endosc. 2010;24:845–853.
    1. Guller U, Hervey S, Purves H, Muhlbaier LH, Peterson ED, Eubanks S, Pietrobon R. Laparoscopic versus open appendectomy: outcomes comparison based on a large administrative database. Ann Surg. 2004;239:43–52.
    1. Moberg AC, Berndsen F, Palmquist I, Petersson U, Resch T, Montgomery A. Randomized clinical trial of laparoscopic versus open appendicectomy for confirmed appendicitis. Br J Surg. 2005;92:298–304.
    1. Pedersen AG, Petersen OB, Wara P, Rønning H, Qvist N, Laurberg S. Randomized clinical trial of laparoscopic versus open appendicectomy. Br J Surg. 2001;88:200–205.
    1. Kouhia ST, Heiskanen JT, Huttunen R, Ahtola HI, Kiviniemi VV, Hakala T. Long-term follow-up of a randomized clinical trial of open versus laparoscopic appendicectomy. Br J Surg. 2010;97:1395–1400.
    1. Tiwari MM, Reynoso JF, Tsang AW, Oleynikov D. Comparison of outcomes of laparoscopic and open appendectomy in management of uncomplicated and complicated appendicitis. Ann Surg. 2011;254:927–932.
    1. Brügger L, Rosella L, Candinas D, Güller U. Improving outcomes after laparoscopic appendectomy: a population-based, 12-year trend analysis of 7446 patients. Ann Surg. 2011;253:309–313.
    1. Ball CG, Kortbeek JB, Kirkpatrick AW, Mitchell P. Laparoscopic appendectomy for complicated appendicitis: an evaluation of postoperative factors. Surg Endosc. 2004;18:969–973.
    1. Towfigh S, Chen F, Mason R, Katkhouda N, Chan L, Berne T. Laparoscopic appendectomy significantly reduces length of stay for perforated appendicitis. Surg Endosc. 2006;20:495–499.
    1. Sahm M, Pross M, Otto R, Koch A, Gastinger I, Lippert H. Clinical Health Service Research on the Surgical Therapy of Acute Appendicitis: Comparison of Outcomes Based on 3 German Multicenter Quality Assurance Studies Over 21 Years. Ann Surg. 2015;262:338–346.
    1. Mentula P, Sammalkorpi H, Leppäniemi A. Laparoscopic Surgery or Conservative Treatment for Appendiceal Abscess in Adults? A Randomized Controlled Trial. Ann Surg. 2015;262:237–242.
    1. Ingraham AM, Cohen ME, Bilimoria KY, Pritts TA, Ko CY, Esposito TJ. Comparison of outcomes after laparoscopic versus open appendectomy for acute appendicitis at 222 ACS NSQIP hospitals. Surgery. 2010;148:625–635; discussion 635-637.
    1. Bulian DR, Kaehler G, Magdeburg R, Butters M, Burghardt J, Albrecht R, Bernhardt J, Heiss MM, Buhr HJ, Lehmann KS. Analysis of the First 217 Appendectomies of the German NOTES Registry. Ann Surg. 2017;265:534–538.
    1. Wood SG, Panait L, Duffy AJ, Bell RL, Roberts KE. Complications of transvaginal natural orifice transluminal endoscopic surgery: a series of 102 patients. Ann Surg. 2014;259:744–749.
    1. Ingraham AM, Cohen ME, Bilimoria KY, Ko CY, Hall BL, Russell TR, Nathens AB. Effect of delay to operation on outcomes in adults with acute appendicitis. Arch Surg. 2010;145:886–892.
    1. Norton VC, Schriger DL. Effect of transfer on outcome in patients with appendicitis. Ann Emerg Med. 1997;29:467–473.
    1. Teixeira PG, Sivrikoz E, Inaba K, Talving P, Lam L, Demetriades D. Appendectomy timing: waiting until the next morning increases the risk of surgical site infections. Ann Surg. 2012;256:538–543.
    1. Nagpal K, Udgiri N, Sharma N, Curras E, Cosgrove JM, Farkas DT. Delaying an appendectomy: is it safe? Am Surg. 2012;78:897–900.
    1. Kanona H, Al Samaraee A, Nice C, Bhattacharya V. Stump appendicitis: a review. Int J Surg. 2012;10:425–428.
    1. Perri S, Amendolara M, Gallo G, Valenti G, Meneghini G, Gelmi GF. [Laparoscopic appendectomy in clinical practice. Aesthetic and functional advantages] G Chir. 1993;14:313–319.
    1. Beldi G, Vorburger SA, Bruegger LE, Kocher T, Inderbitzin D, Candinas D. Analysis of stapling versus endoloops in appendiceal stump closure. Br J Surg. 2006;93:1390–1393.
    1. Sohn M, Hoffmann M, Pohlen U, Lauscher JC, Zurbuchen U, Holmer C, Buhr HJ, Lehmann KS. [Stump closure in laparoscopic appendectomy. Influence of endoloop or linear stapler on patient outcome] Chirurg. 2014;85:46–50.
    1. Guzman MJ, Gitelis ME, Linn JG, Ujiki MB, Waskerwitz M, Umanskiy K, Muldoon JP. A Model of Cost Reduction and Standardization: Improved Cost Savings While Maintaining the Quality of Care. Dis Colon Rectum. 2015;58:1104–1107.
    1. Matyja M, Strzałka M, Rembiasz K. Laparosocopic Appendectomy, Cost-Effectiveness of Three Different Techniques Used to Close the Appendix Stump. Pol Przegl Chir. 2015;87:634–637.
    1. Horvath P, Lange J, Bachmann R, Struller F, Königsrainer A, Zdichavsky M. Comparison of clinical outcome of laparoscopic versus open appendectomy for complicated appendicitis. Surg Endosc. 2017;31:199–205.
    1. Fleming FJ, Kim MJ, Messing S, Gunzler D, Salloum R, Monson JR. Balancing the risk of postoperative surgical infections: a multivariate analysis of factors associated with laparoscopic appendectomy from the NSQIP database. Ann Surg. 2010;252:895–900.
    1. Lygidakis NJ. Surgical approaches to peritonitis. The value of intra- and postoperative peritoneal lavage. Acta Chir Belg. 1983;83:345–352.
    1. Uematsu D, Akiyama G, Magishi A, Sano T, Niitsu H, Narita M, Komatsu H. Laparoscopic Hartmann’s procedure for fecal peritonitis resulting from perforation of the left-sided colon in elderly and severely ill patients. Tech Coloproctol. 2012;16:243–246.
    1. Faranda C, Barrat C, Catheline JM, Champault GG. Two-stage laparoscopic management of generalized peritonitis due to perforated sigmoid diverticula: eighteen cases. Surg Laparosc Endosc Percutan Tech. 2000;10:135–138; discussion 139-141.
    1. Bhangu A, Singh P, Lundy J, Bowley DM. Systemic review and meta-analysis of randomized clinical trials comparing primary vs delayed primary skin closure in contaminated and dirty abdominal incisions. JAMA Surg. 2013;148:779–786.
    1. Siribumrungwong B, Srikuea K, Thakkinstian A. Comparison of superficial surgical site infection between delayed primary and primary wound closures in ruptured appendicitis. Asian J Surg. 2014;37:120–124.
    1. Rucinski J, Fabian T, Panagopoulos G, Schein M, Wise L. Gangrenous and perforated appendicitis: a meta-analytic study of 2532 patients indicates that the incision should be closed primarily. Surgery. 2000;127:136–141.
    1. Cohn SM, Giannotti G, Ong AW, Varela JE, Shatz DV, McKenney MG, Sleeman D, Ginzburg E, Augenstein JS, Byers PM, et al. Prospective randomized trial of two wound management strategies for dirty abdominal wounds. Ann Surg. 2001;233:409–413.
    1. Siribumrungwong B, Noorit P, Wilasrusmee C, Thakkinstian A. A systematic review and meta-analysis of randomised controlled trials of delayed primary wound closure in contaminated abdominal wounds. World J Emerg Surg. 2014;9:49.
    1. Markides G, Subar D, Riyad K. Laparoscopic versus open appendectomy in adults with complicated appendicitis: systematic review and meta-analysis. World J Surg. 2010;34:2026–2040.
    1. Senekjian L, Nirula R. Tailoring the operative approach for appendicitis to the patient: a prediction model from national surgical quality improvement program data. J Am Coll Surg. 2013;216:34–40.
    1. Romy S, Eisenring MC, Bettschart V, Petignat C, Francioli P, Troillet N. Laparoscope use and surgical site infections in digestive surgery. Ann Surg. 2008;247:627–632.
    1. Rosser JC Jr, Lynch PJ, Cuddihy L, Gentile DA, Klonsky J, Merrell R. The impact of video games on training surgeons in the 21st century. Arch Surg. 2007;142:181–186; discusssion 186.
    1. Badurdeen S, Abdul-Samad O, Story G, Wilson C, Down S, Harris A. Nintendo Wii video-gaming ability predicts laparoscopic skill. Surg Endosc. 2010;24:1824–1828.
    1. Glassman D, Yiasemidou M, Ishii H, Somani BK, Ahmed K, Biyani CS. Effect of Playing Video Games on Laparoscopic Skills Performance: A Systematic Review. J Endourol. 2016;30:146–152.
    1. Middleton KK, Hamilton T, Tsai PC, Middleton DB, Falcone JL, Hamad G. Improved nondominant hand performance on a laparoscopic virtual reality simulator after playing the Nintendo Wii. Surg Endosc. 2013;27:4224–4231.
    1. Ju R, Chang PL, Buckley AP, Wang KC. Comparison of Nintendo Wii and PlayStation2 for enhancing laparoscopic skills. JSLS. 2012;16:612–618.
    1. Overtoom EM, Jansen FW, van Santbrink EJ, Schraffordt Koops SE, Veersema S, Schreuder HW. Training in Basic Laparoscopic Surgical Skills: Residents Opinion of the New Nintendo Wii-U Laparoscopic Simulator. J Surg Educ. 2017;74:352–359.
    1. Jalink MB, Goris J, Heineman E, Pierie JP, ten Cate Hoedemaker HO. Construct and concurrent validity of a Nintendo Wii video game made for training basic laparoscopic skills. Surg Endosc. 2014;28:537–542.
    1. Bokhari R, Bollman-McGregor J, Kahoi K, Smith M, Feinstein A, Ferrara J. Design, development, and validation of a take-home simulator for fundamental laparoscopic skills: using Nintendo Wii for surgical training. Am Surg. 2010;76:583–586.
    1. Wakasugi M, Tsujimura N, Nakahara Y, Matsumoto T, Takemoto H, Takachi K, Nishioka K, Oshima S. Single-incision laparoscopically assisted appendectomy performed by residents is safe and feasible: A single institution, retrospective case series. Ann Med Surg (Lond) 2017;15:43–46.
    1. Graat LJ, Bosma E, Roukema JA, Heisterkamp J. Appendectomy by residents is safe and not associated with a higher incidence of complications: a retrospective cohort study. Ann Surg. 2012;255:715–719.
    1. Lin YY, Shabbir A, So JB. Laparoscopic appendectomy by residents: evaluating outcomes and learning curve. Surg Endosc. 2010;24:125–130.
    1. Albright JB, Fakhre GP, Nields WW, Metzger PP. Incidental appendectomy: 18-year pathologic survey and cost effectiveness in the nonmanaged-care setting. J Am Coll Surg. 2007;205:298–306.
    1. Ochsner A. The cause of diffuse peritonitis complicating appendicitis and its prevention. JAMA. 1901;26:1747–1754.
    1. Willemsen PJ, Hoorntje LE, Eddes EH, Ploeg RJ. The need for interval appendectomy after resolution of an appendiceal mass questioned. Dig Surg. 2002;19:216–220; discussion 221.
    1. Ahmed I, Deakin D, Parsons SL. Appendix mass: do we know how to treat it? Ann R Coll Surg Engl. 2005;87:191–195.
    1. Mosegaard A, Nielsen OS. Interval appendectomy. A retrospective study. Acta Chir Scand. 1979;145:109–111.
    1. Foran B, Berne TV, Rosoff L. Management of the appendiceal mass. Arch Surg. 1978;113:1144–1145.
    1. Engkvist O. Appendectomy à froid a superfluous routine operation? Acta Chir Scand. 1971;137:797–800.
    1. Tekin A, Kurtoğlu HC, Can I, Oztan S. Routine interval appendectomy is unnecessary after conservative treatment of appendiceal mass. Colorectal Dis. 2008;10:465–468.
    1. Eriksson S, Granström L. Randomized controlled trial of appendicectomy versus antibiotic therapy for acute appendicitis. Br J Surg. 1995;82:166–169.
    1. Styrud J, Eriksson S, Nilsson I, Ahlberg G, Haapaniemi S, Neovius G, Rex L, Badume I, Granström L. Appendectomy versus antibiotic treatment in acute appendicitis. a prospective multicenter randomized controlled trial. World J Surg. 2006;30:1033–1037.
    1. Thomas DR. Conservative management of the appendix mass. Surgery. 1973;73:677–680.
    1. Eriksson S, Styrud J. Interval appendicectomy: a retrospective study. Eur J Surg. 1998;164:771–774; discussion 775.
    1. Hoffmann J. Contemporary management of appendiceal mass. Br J Surg. 1993;80:1350.
    1. Corfield L. Interval appendicectomy after appendiceal mass or abscess in adults: what is “best practice”? Surg Today. 2007;37:1–4.
    1. Paull DL, Bloom GP. Appendiceal abscess. Arch Surg. 1982;117:1017–1019.
    1. Kaminski A, Liu IL, Applebaum H, Lee SL, Haigh PI. Routine interval appendectomy is not justified after initial nonoperative treatment of acute appendicitis. Arch Surg. 2005;140:897–901.
    1. Yamini D, Vargas H, Bongard F, Klein S, Stamos MJ. Perforated appendicitis: is it truly a surgical urgency? Am Surg. 1998;64:970–975.
    1. Margenthaler JA, Longo WE, Virgo KS, Johnson FE, Oprian CA, Henderson WG, Daley J, Khuri SF. Risk factors for adverse outcomes after the surgical treatment of appendicitis in adults. Ann Surg. 2003;238:59–66.
    1. Andersen BR, Kallehave FL, Andersen HK. Antibiotics versus placebo for prevention of postoperative infection after appendicectomy. Cochrane Database Syst Rev. 2005;(3):CD001439.
    1. Wong PF, Gilliam AD, Kumar S, Shenfine J, O’Dair GN, Leaper DJ. Antibiotic regimens for secondary peritonitis of gastrointestinal origin in adults. Cochrane Database Syst Rev. 2005;(2):CD004539.
    1. López JJ, Deans KJ, Minneci PC. Nonoperative management of appendicitis in children. Curr Opin Pediatr. 2017;29:358–362.
    1. Georgiou R, Eaton S, Stanton MP, Pierro A, Hall NJ. Efficacy and Safety of Nonoperative Treatment for Acute Appendicitis: A Meta-analysis. Pediatrics. 2017;139:pii: e20163003.
    1. Gonzalez DO, Deans KJ, Minneci PC. Role of non-operative management in pediatric appendicitis. Semin Pediatr Surg. 2016;25:204–207.
    1. Kumar S, Jain S. Treatment of appendiceal mass: prospective, randomized clinical trial. Indian J Gastroenterol. 2004;23:165–167.
    1. Park HC, Kim MJ, Lee BH. Antibiotic therapy for appendicitis in patients aged ≥80 years. Am J Med. 2014;127:562–564.
    1. Parmentier B, Berrebi D, Peycelon M, Doit C, Ghoneimi AE, Bonnard A. Failure of First-Line Antibiotics in Nonoperative Management of Appendiceal Mass, toward a Second-Line Instead of Surgery? Eur J Pediatr Surg. 2016;26:267–272.
    1. de Kraker ME, Wolkewitz M, Davey PG, Koller W, Berger J, Nagler J, Icket C, Kalenic S, Horvatic J, Seifert H, et al. Burden of antimicrobial resistance in European hospitals: excess mortality and length of hospital stay associated with bloodstream infections due to Escherichia coli resistant to third-generation cephalosporins. J Antimicrob Chemother. 2011;66:398–407.
    1. Sadot E, Telem DA, Arora M, Butala P, Nguyen SQ, Divino CM. Laparoscopy: a safe approach to appendicitis during pregnancy. Surg Endosc. 2010;24:383–389.
    1. McGory ML, Zingmond DS, Tillou A, Hiatt JR, Ko CY, Cryer HM. Negative appendectomy in pregnant women is associated with a substantial risk of fetal loss. J Am Coll Surg. 2007;205:534–540.
    1. Wilasrusmee C, Sukrat B, McEvoy M, Attia J, Thakkinstian A. Systematic review and meta-analysis of safety of laparoscopic versus open appendicectomy for suspected appendicitis in pregnancy. Br J Surg. 2012;99:1470–1478.
    1. Wei L, Macdonald TM, Shimi SM. Appendicectomy is associated with increased pregnancy rate: a cohort study. Ann Surg. 2012;256:1039–1044.
    1. Bucher P, Mathe Z, Demirag A, Morel P. Appendix tumors in the era of laparoscopic appendectomy. Surg Endosc. 2004;18:1063–1066.
    1. Wright GP, Mater ME, Carroll JT, Choy JS, Chung MH. Is there truly an oncologic indication for interval appendectomy? Am J Surg. 2015;209:442–446.
    1. Wu JX, Dawes AJ, Sacks GD, Brunicardi FC, Keeler EB. Cost effectiveness of nonoperative management versus laparoscopic appendectomy for acute uncomplicated appendicitis. Surgery. 2015;158:712–721.
    1. Needham PJ, Laughlan KA, Botterill ID, Ambrose NS. Laparoscopic appendicectomy: calculating the cost. Ann R Coll Surg Engl. 2009;91:606–608.
    1. Uzman S, Donmez T, Erdem VM, Hut A, Yildirim D, Akinci M. Combined spinal-epidural anesthesia in laparoscopic appendectomy: a prospective feasibility study. Ann Surg Treat Res. 2017;92:208–213.
    1. Hamill JK, Liley A, Hill AG. Intraperitoneal Local Anesthetic for Laparoscopic Appendectomy in Children: A Randomized Controlled Trial. Ann Surg. 2017;266:189–194.
    1. Sumiyoshi R. [Preoperative fasting and fluid management in pediatric patients] Masui. 2013;62:1045–1052.
    1. Chau-in W, Hintong T, Rodanant O, Lekprasert V, Punjasawadwong Y, Charuluxananan S, Tanudsintum S. Anesthesia-related complications of caesarean delivery in Thailand: 16,697 cases from the Thai Anaesthesia Incidents Study. J Med Assoc Thai. 2010;93:1274–1283.
    1. Perez J, Barone JE, Wilbanks TO, Jorgensson D, Corvo PR. Liberal use of computed tomography scanning does not improve diagnostic accuracy in appendicitis. Am J Surg. 2003;185:194–197.
    1. Nosé Y. Japanese government saves hemodialysis patients’ lives. Artif Organs. 1998;22:815.
    1. Hori T, Kaido T, Iida T, Yagi S, Uemoto S. Comprehensive guide to laparoscope-assisted graft harvesting in live donors for living-donor liver transplantation: perspective of laparoscopic vision. Ann Gastroenterol. 2017;30:118–126.
    1. Di Saverio S, Birindelli A, Kelly MD, Catena F, Weber DG, Sartelli M, Sugrue M, De Moya M, Gomes CA, Bhangu A, et al. WSES Jerusalem guidelines for diagnosis and treatment of acute appendicitis. World J Emerg Surg. 2016;11:34.
    1. Agresta F, De Simone P, Leone L, Arezzo A, Biondi A, Bottero L, Catena F, Conzo G, Del Genio G, Fersini A, Guerrieri M, Illomei G, Tonelli P, Vitellaro M, Docimo G, Crucitti A; Italian Society Of Young Surgeons (SPIGC) Laparoscopic appendectomy in Italy: an appraisal of 26,863 cases. J Laparoendosc Adv Surg Tech A. 2004;14:1–8.
    1. Biondi A, Di Stefano C, Ferrara F, Bellia A, Vacante M, Piazza L. Laparoscopic versus open appendectomy: a retrospective cohort study assessing outcomes and cost-effectiveness. World J Emerg Surg. 2016;11:44.

Source: PubMed

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