Treatment of Psoriasis: Novel Approaches to Topical Delivery

Uwe Wollina, Michael Tirant, Aleksandra Vojvodic, Torello Lotti, Uwe Wollina, Michael Tirant, Aleksandra Vojvodic, Torello Lotti

Abstract

Topical treatment is the cornerstone for the management of mild to moderate psoriasis. Despite efforts in drug development, patient's satisfaction with the available topical treatments is limited. A strategy to improve safety, efficacy and comfort of topical treatment provides the development of new drug delivery and drug carrier systems. This review provides an overview of recent advances in this field with a focus on psoriasis. Laser-assisted drug delivery, foam formulations, nanoparticles, ethosomes, and niomes are considered. Hopefully, these new developments will improve topical drug therapy and patient satisfaction.

Keywords: Ethosomes; Foams; Laser-assisted drug delivery; Nanoparticles; Niosomes; Psoriasis; Topical drug therapy.

Copyright: © 2019 Uwe Wollina, Michael Tirant, Aleksandra Vojvodic, Torello Lotti.

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Source: PubMed

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