Urodynamics, the supine empty bladder stress test, and incontinence severity
Charles W Nager, Stephen R Kraus, Kim Kenton, Larry Sirls, Toby C Chai, Clifford Wai, Gary Sutkin, Wendy Leng, Heather Litman, Liyuan Huang, Sharon Tennstedt, Holly E Richter, Urinary Incontinence Treatment Network, Elizabeth A Gormley, Larry Sirls, Salil Khandwala, Linda Brubaker, Kimberly Kenton, Holly E Richter, L Keith Lloyd, Michael Albo, Charles Nager, Toby C Chai, Harry W Johnson, Halina M Zyczynski, Wendy Leng, Philippe Zimmern, Gary Lemack, Stephen Kraus, Thomas Rozanski, Peggy Norton, Ingrid Nygaard, Sharon Tennstedt, Anne Stoddard, Debuene Chang, Marva Moxey-Mims, Rebekah Rasooly, Amy Arisco, Jan Baker, Diane Borello-France, Kathryn L Burgio, Ananias Diokno, Melissa Fischer, MaryPat Fitzgerald, Chiara Ghetti, Patricia S Goode, Robert L Holley, Margie Kahn, Jerry Lowder, Karl Luber, Emily Luckacz, Alayne Markland, Shawn Menefee, Pamela Moalli, Elizabeth Mueller, Pradeep Nagaraju, Kenneth Peters, Elizabeth Sagan, Joseph Schaffer, Amanda Simsiman, Robert Starr, Gary Sutkin, R Edward Varner, Laura Burr, JoAnn Columb, Tamara Dickinson, Rosanna Dinh, Judy Gruss, Alice Howell, Chaandini Jayachandran, Kathy Jesse, D Lynn Kalinoski, Barbara Leemon, Kristen Mangus, Karen Mislanovich, Elva Kelly Moore, Caren Prather, Sylvia Sluder, Mary Tulke, Robin Willingham, Kimberly Woodson, Gisselle Zazueta-Damian, Kimberly J Dandreo, Liyuan Huang, Rose Kowalski, Heather Litman, Marina Mihova, Anne Stoddard, Kerry Tanwar, Sharon Tennstedt, Yan Xu, J Quentin Clemens, Paul Abrams, Diedre Bland, Timothy B Boone, John Connett, Dee Fenner, William Henderson, Sheryl Kelsey, Deborah J Lightner, Deborah Myers, Bassem Wadie, J Christian Winters, Charles W Nager, Stephen R Kraus, Kim Kenton, Larry Sirls, Toby C Chai, Clifford Wai, Gary Sutkin, Wendy Leng, Heather Litman, Liyuan Huang, Sharon Tennstedt, Holly E Richter, Urinary Incontinence Treatment Network, Elizabeth A Gormley, Larry Sirls, Salil Khandwala, Linda Brubaker, Kimberly Kenton, Holly E Richter, L Keith Lloyd, Michael Albo, Charles Nager, Toby C Chai, Harry W Johnson, Halina M Zyczynski, Wendy Leng, Philippe Zimmern, Gary Lemack, Stephen Kraus, Thomas Rozanski, Peggy Norton, Ingrid Nygaard, Sharon Tennstedt, Anne Stoddard, Debuene Chang, Marva Moxey-Mims, Rebekah Rasooly, Amy Arisco, Jan Baker, Diane Borello-France, Kathryn L Burgio, Ananias Diokno, Melissa Fischer, MaryPat Fitzgerald, Chiara Ghetti, Patricia S Goode, Robert L Holley, Margie Kahn, Jerry Lowder, Karl Luber, Emily Luckacz, Alayne Markland, Shawn Menefee, Pamela Moalli, Elizabeth Mueller, Pradeep Nagaraju, Kenneth Peters, Elizabeth Sagan, Joseph Schaffer, Amanda Simsiman, Robert Starr, Gary Sutkin, R Edward Varner, Laura Burr, JoAnn Columb, Tamara Dickinson, Rosanna Dinh, Judy Gruss, Alice Howell, Chaandini Jayachandran, Kathy Jesse, D Lynn Kalinoski, Barbara Leemon, Kristen Mangus, Karen Mislanovich, Elva Kelly Moore, Caren Prather, Sylvia Sluder, Mary Tulke, Robin Willingham, Kimberly Woodson, Gisselle Zazueta-Damian, Kimberly J Dandreo, Liyuan Huang, Rose Kowalski, Heather Litman, Marina Mihova, Anne Stoddard, Kerry Tanwar, Sharon Tennstedt, Yan Xu, J Quentin Clemens, Paul Abrams, Diedre Bland, Timothy B Boone, John Connett, Dee Fenner, William Henderson, Sheryl Kelsey, Deborah J Lightner, Deborah Myers, Bassem Wadie, J Christian Winters
Abstract
Aims: Determine whether urodynamic measures of urethral function [(valsalva leak point pressure (VLPP), maximum urethral closure pressure (MUCP), functional urethral length (FUL)] and the results of the supine empty bladder stress test (SEBST) correlate with each other and with subjective and objective measures of urinary incontinence (UI).
Methods: Data were collected preoperatively from subjects enrolled in a multicenter surgical trial of mid-urethral slings. Subjective measures included questionnaire scores from the Medical Epidemiological and Social Aspects of Aging Questionnaire, Urogenital Distress Inventory, and Incontinence Impact Questionnaire. Objective measures included a 24-hr pad weight test, incontinence episode frequency on a 3-day voiding diary, and a SEBST.
Results: Five hundred ninety-seven women enrolled. Three hundred seventy-two women had valid VLPP values; 539 had valid MUCP/FUL values. Subjective measures of severity had weak to moderate correlation with each other (r = 0.25-0.43) and with objective measures of severity (r = -0.06 to 0.45). VLPP and MUCP had moderate correlation with each other (r = 0.36, P< 0.001). Urodynamic measures of urethral function had little or no correlation with subjective or objective measures of severity. Subjects with a positive SEBST had more subjective and objective severity measures compared to the negative SEBST group, but they did not have significantly different VLPP and MUCP values.
Conclusions: VLPP and MUCP have moderate correlation with each other, but each had little or no correlation with subjective or objective measures of severity or with the results of the SEBST. This data suggests that the urodynamic measures of urethral function are not related to subjective or objective measures of UI severity.
Trial registration: ClinicalTrials.gov NCT00325039.
© 2010 Wiley-Liss, Inc.
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Source: PubMed