Effect of transcranial direct current stimulation on sports performance for two profiles of athletes (power and endurance) (COMPETE): a protocol for a randomised, crossover, double blind, controlled exploratory trial

Yohan Grandperrin, Sidney Grosprêtre, Magali Nicolier, Philippe Gimenez, Chrystelle Vidal, Emmanuel Haffen, Djamila Bennabi, Yohan Grandperrin, Sidney Grosprêtre, Magali Nicolier, Philippe Gimenez, Chrystelle Vidal, Emmanuel Haffen, Djamila Bennabi

Abstract

Background: Transcranial direct current stimulation (tDCS) is promising for improving motor and cognitive performance. Nevertheless, its mechanisms of action are unclear and need to be better characterised according to the stimulated brain area and the type of exercise performed.

Methods/design: This is a double-blind crossover study, organised into two parts: the first is to assess the effects of tDCS on explosive performance (jump task) and the second is to assess the effects on endurance performance (cycling time trial task). Participants, who are recreationally active or athletes (parkour practitioners, cyclists), will receive two active tDCS sessions (over the left dorsolateral prefrontal cortex and right motor cortex) and one sham tDCS session (part A), or two sequences (one active and one sham) of two daily tDCS sessions over 5 days (part B). Motor and cognitive performance will be compared before and after tDCS sessions (part A), and before and after the first session, after the last session and at day 12 and day 30 of each tDCS sequence (part B).

Discussion: This study investigates the acute and repeated effects of tDCS on the motor and cognitive performance of healthy subjects. It will try to evaluate if tDCS could be considered as a neuroenhancement technology according to the physical task investigated (endurance versus explosive).

Trial registration: ClinicalTrials.gov, NCT03937115. Registered on 3 May 2019; retrospectively registered.

Keywords: Cycling; Dorsolateral prefrontal cortex; Endurance performance; Explosive performance; Parkour; Primary motor cortex; Transcranial direct current stimulation.

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Study flow diagram (part A)
Fig. 2
Fig. 2
Study flow diagram (part B)
Fig. 3
Fig. 3
Randomised crossover design for COMPETE (part A) (Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) Figure). BART Balloon Analog Risk Task, BIS-10 Barratt Impulsiveness Scale-10, dlPFC dorsolateral prefrontal cortex, EEfRT Effort Expenditure for Rewards Task, M1 primary motor cortex, MCQ Monetary Choice Questionnaire, QIDS-C16 16-Item Quick Inventory of Depressive Symptomatology, Clinician Rating, QIDS-SR16 16-Item Quick Inventory of Depressive Symptomatology, Self-Report
Fig. 4
Fig. 4
Randomised cross-over design for COMPETE (part B) (Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) Figure). BART Balloon Analog Risk Task, BIS-10 Barratt Impulsiveness Scale-10, dlPFC dorsolateral prefrontal cortex, EEfRT Effort Expenditure for Rewards Task, M1 primary motor cortex, MCQ Monetary Choice Questionnaire, QIDS-C16 16-Item Quick Inventory of Depressive Symptomatology, Clinician Rating, QIDS-SR16 16-Item Quick Inventory of Depressive Symptomatology, Self-Report

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Source: PubMed

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