- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00902096
Predictors of Cord Blood Immunoglobin E (IgE) Levels
Background: Increased total serum IgE levels are a common characteristic of atopic diseases. Increased cord blood IgE levels, in conjunction with a family history of atopy, are associated with the development of allergic diseases in children. However, little is known about predictors of cord blood IgE levels.
Objective: The aim of our study was to identify predictors of cord blood IgE levels in an ongoing large birth cohort of infants with or without a family history of atopy.
Methods: Blood sampling of mothers was performed just before the delivery of newborns. Cord blood was also collected when the child was born. Maternal and cord blood was measured for IgE levels and cytokines. Questionnaires were administered after birth of the infant.
Study Overview
Status
Conditions
Study Type
Enrollment (Anticipated)
Contacts and Locations
Study Contact
- Name: Chien-Han Chen, MD
- Phone Number: 2004 886-3-3179599
- Email: chinsword@yahoo.com.tw
Study Locations
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-
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Taoyuan, Taiwan
- Recruiting
- Min-Sheng General Hospital
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Contact:
- Chien-Han Chen, MD
- Email: chinsword@yahoo.com.tw
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Principal Investigator:
- Chien-Han Chen, MD
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-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
- Older Adult
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion Criteria:
- Mothers in pregnancy 18 years of age or older, AND
- Mothers able to speak Chinese.
Exclusion Criteria:
- Infant delivered at less than 36 weeks' gestation,
- Infant with Apgar score in 5 minutes after birth < 7,
- Infant with a major congenital anomaly, OR
- Infant admitted to an intensive care unit.
Study Plan
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
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Prenatal factors
Prenatal factors to predict cord blood IgE
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
cord blood IgE
Time Frame: at birth
|
at birth
|
Secondary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Cord blood cytokines or other mediators
Time Frame: at birth
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at birth
|
Collaborators and Investigators
Sponsor
Investigators
- Principal Investigator: Chien-Han Chen, MD, Min-Sheng General Hospital
Study record dates
Study Major Dates
Study Start
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Other Study ID Numbers
- 2009008
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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