- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01123018
Screening for Memory Studies
August 24, 2026 updated by: John Wesson Ashford Jr
We hope to recruit participants into various clinical trials and research projects.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
The purpose of this protocol is to advertise, recruit, and do a preliminary screen for various clinical trials.
Anonymous information collected will be entered in a database available to researchers connected with the Stanford/VA Aging Clinical Research Center, located at VA Palo Alto Health Care System, Palo Alto Division.
Study Type
Observational
Enrollment (Actual)
1
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
California
-
Palo Alto, California, United States, 94304
- VA Palo Alto Health Care System
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
55 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
Yes
Sampling Method
Probability Sample
Study Population
healthy older adults with memory concerns
Description
Inclusion Criteria:
- Age 21 or over.
Exclusion Criteria:
- Major psychiatric problems.
- Major medical problems.
- Aversion to test-taking.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
|---|---|
|
Older Adults
Persons over age 60 Participants will complete the Memtrax memory screening test
|
Memory Screening test
Other Names:
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Memory Impairment
Time Frame: 90 seconds to 150 seconds (normal less than 100 seconds)
|
The primary outcome measure on a 50 item Continuous Recognition Task with 25 repeated items, first display of an item is 3 seconds, new image immediately after a response (MemTrax, see: reference), is number of HITs (a memory measure).
Less than 20 suggests memory impairment and will trigger referral to a memory study.
|
90 seconds to 150 seconds (normal less than 100 seconds)
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Processing speed measurement with MemTrax
Time Frame: 90 - 150 seconds (normal - 95 seconds)
|
Secondary outcome measure is response time to HITs (a measure of memory processing speed), usually 0.550 to 1.5 seconds.
Slower than 1.2 seconds suggests a memory, attention, or processing speed problem, will also trigger a referral to the memory study.
Note, a third measure, number of Correct Rejections (a measure of executive function), is used to validate the first and second outcome measures.
Values below 20 suggest that the other measures might not be valid.
|
90 - 150 seconds (normal - 95 seconds)
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Collaborators
Investigators
- Principal Investigator: J. Wesson Ashford Jr., MD, PhD, Stanford University
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
General Publications
- Ashford JW, Borson S. Primary care screening for dementia and mild cognitive impairment. JAMA. 2008 Mar 12;299(10):1132-3; author reply 1133-4. doi: 10.1001/jama.299.10.1132-b. No abstract available.
- Clifford JO Jr, Anand S, Tarpin-Bernard F, Bergeron MF, Ashford CB, Bayley PJ, Ashford JW. Episodic memory assessment: effects of sex and age on performance and response time during a continuous recognition task. Front Hum Neurosci. 2024 Apr 4;18:1304221. doi: 10.3389/fnhum.2024.1304221. eCollection 2024.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
June 1, 2007
Primary Completion (Actual)
December 1, 2023
Study Completion (Actual)
December 1, 2023
Study Registration Dates
First Submitted
May 11, 2010
First Submitted That Met QC Criteria
May 12, 2010
First Posted (Estimated)
May 13, 2010
Study Record Updates
Last Update Posted (Actual)
August 26, 2026
Last Update Submitted That Met QC Criteria
August 24, 2026
Last Verified
August 1, 2026
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
- Neurologic Manifestations
- Brain Diseases
- Central Nervous System Diseases
- Nervous System Diseases
- Mental Disorders
- Neurobehavioral Manifestations
- Neurocognitive Disorders
- Tauopathies
- Neurodegenerative Diseases
- Pathological Conditions, Signs and Symptoms
- Signs and Symptoms
- Alzheimer Disease
- Dementia
- Memory Disorders
Other Study ID Numbers
- SU-06302009-2900
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
UNDECIDED
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.