Referral Patterns for Hospital Acquired Acute Kidney Injury and Relevance to Renal Outcomes (HA-AKI)

June 25, 2010 updated by: Centre Hospitalier Universitaire Vaudois
Few studies analyzed the referral time to nephrologists and its impact on the patient outcome in a large cohort. The investigators described the incidence and determined the outcome with respect to renal function recovery, renal replacement therapy (RRT) requirement and in-hospital mortality of Hospital Acquired Acute Kidney Injury (HA-AKI) without nephrology referral (nrHA-AKI) and late referred HA-AKI patients to nephrologists (lrHA-AKI) compared with early referral patients (erHA-AKI). The patients included were admitted to the tertiary care academic center of Lausanne (Switzerland) between 2004 and 2008, in the medical and surgical services and in the intensive care unit (ICU).

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Switzerland
      • Sion, Switzerland, 1951
        • Nephrology - CHCVs

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 90 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Probability Sample

Study Population

This study population consisted of patients who were hospitalized in the medical and surgical departments as well as in the intensive care untis (ICU) of the University Hospital of Lausanne (Centre Hospitalier Universitaire Vaudois [CHUV]) that is a tertiary care academic medical center. Patients with AKI coming from ICU in the medicine or surgery wards, and patients from medicine or surgery wards, who required a transfer to ICU during the hospital stay, were also included whatever the cause of the transfer.

Description

Inclusion Criteria:

  • Adult patients.
  • Hospitalization in the medicine and surgery wards and in the intensive care unit.
  • Hospitalized patients with acquired acute kidney injury according to the
  • Acute Kidney Injury Network (AKIN)criteria.
  • HA-AKI patients with no referral to the nephrologist (nrHA-AKI).
  • HA-AKI patients referred late (more than five days [> 5 days]) to the nephrologist (lrHA-AKI).
  • HA-AKI patients early referred (within five days after sCr increase) to the nephrologist (erHA-AKI).

Exclusion Criteria:

  • Patients with AKI at the time of the hospital admission and during the first
  • 48 hours after admission.
  • Patients hospitalized in other wards.
  • Children under 18.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
nrHA-AKI patients
Patients with hospital-acquired acute kidney injury not referred to the nephrologists
Other: Nephrologist referral
Nephrologist specialty, renal replacement therapy
Other Names:
  • Control group: early-referred patients with HA-AKI.
lrHA-AKI patients
Patients with hospital-acquired acute kidney injury whao are late referred to the nephrologists
Other: Nephrologist referral
Nephrologist specialty, renal replacement therapy
Other Names:
  • Control group: early-referred patients with HA-AKI.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Referral patterns for hospital acquired acute kidney injury and relevance to renal outcomes
Recovery of renal function during hospital stay. Requirement for renal replacement therapy.

Secondary Outcome Measures

Outcome Measure
Measure Description
Referral patterns for hospital acquired acute kidney injury and relevance to renal outcomes
Length of hospital stay. In-hospital mortality.

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Centre Hospitalier Universitaire Vaudois

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

First Submitted

June 23, 2010

First Submitted That Met QC Criteria

June 25, 2010

First Posted (Estimate)

June 28, 2010

Study Record Updates

Last Update Posted (Estimate)

June 28, 2010

Last Update Submitted That Met QC Criteria

June 25, 2010

Last Verified

August 1, 2010

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • HA-AKI referral

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Subscribe