Exploration of Fatigue, Uncertainty, Depression and Quality of Life in Heart Transplantation Recipients

Exploration of Fatigue ,Uncertainty ,Depression and Quality of Life in Heart Transplantation Recipients

The purpose of this study is to explore the fatigue, uncertainty, depression and quality of life in heart transplant recipients, and associated factors of quality of life .

Study Overview

• Status: Completed
• Conditions: Heart Transplantation

Detailed Description

The purpose of this study is to explore the symptom distress, fatigue, depression, uncertainty, and quality of life in heart transplant recipients, and associated factors of quality of life (QOL). The eligible patients are (1)who undergone heart transplantation were recruited from the Department of Cardiac Surgery, Nation Taiwan University Hospital,(2)18 year old or older. A set of questionnaire with the Transplant Symptom Frequency and Symptom Distress Scale, Hospital Anxiety and Depression Scale (HADS) , Fatigue Symptom Inventory (FSI), Mishel's Uncertainty Scale, and 12-item Short-Form Health Survey (SF-12) were used to collected symptom distress, fatigue, depression, uncertainty, and QOL .

• Study Type: Observational
• Enrollment (Actual): 127

Contacts and Locations

Study Locations

• Taiwan
  • Taipei, Taiwan, 10051
    • National Taiwan University Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

The outpatients who undergone heart transplantation were recruited from the Department of Cardiac Surgery

Description

Inclusion Criteria:

• Clinical diagnosis of heart transplantation
• Adults 18 years of age

Exclusion Criteria:

• The woman who are pregnant

Study Plan

How is the study designed?

Design Details

• Observational Models: Case-Only
• Time Perspectives: Cross-Sectional

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort
heart transplantation

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
The SF12 Health survey	It was used to measure quality of life	1 month
Transplant Symptom Frequency and Symptom Distress Scale	it was used to measure symptom distress.	1 week
Fatigue Symptom Inventory	It was used to measure level of fatigue.	1 week
Hospital Anxiety and Depression Scale (HADS)	It was used to measure level of anxiety and depression.	1month
Illness Uncertainty Scale	It was used to measure level of uncertainty.	1 month

Collaborators and Investigators

• Sponsor: National Taiwan University Hospital

Study record dates

Study Major Dates

• Study Start: October 1, 2008
• Primary Completion (Actual): August 1, 2009
• Study Completion (Actual): August 1, 2009

Study Registration Dates

• First Submitted: August 24, 2009
• First Submitted That Met QC Criteria: August 16, 2010
• First Posted (Estimate): August 17, 2010

Study Record Updates

• Last Update Posted (Estimate): August 30, 2010
• Last Update Submitted That Met QC Criteria: August 27, 2010
• Last Verified: August 1, 2010

More Information

Terms related to this study

• Keywords: Depression; Fatigue; Heart Transplantation; Symptom Distress; Quality Of Life.
• Additional Relevant MeSH Terms: Behavioral Symptoms; Depression; Fatigue
• Other Study ID Numbers: 200808050R

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No