Efficacy of Methylsulfonylmethane Supplementation on Osteoarthritis of The Knee: A Randomized Controlled Study
August 24, 2010 updated by: Assaf-Harofeh Medical Center
The aim of this study was to determine the efficacy of methylsulfonylmethane (MSM) in treating patients with knee OA.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Study Type
Interventional
Phase
- Not Applicable
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
36 years to 66 years (Adult, Older Adult)
Accepts Healthy Volunteers
N/A
Genders Eligible for Study
All
Description
Inclusion Criteria:
- symptomatic knee OA for at least 6 months according to the clinical criteria of the American College of Rheumatology (ACR)
- radiographic confirmed knee OA according to the Kellgren & Lawrence scale
Exclusion Criteria:
- acute septic arthritis
- inflammatory arthritis
- any other type of arthritis
- history of knee buckling or recent knee injury
- lack of physical or mental bility to perform or comply with the treatment procedure
- diabetes mellitus
- fibromyalgia or other chronic pain syndromes
- concurrent anti-coagulant/anti-platelet drugs
- arthroscopy or intra-articular injections in the previous 3 months
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: Purified MSM
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
|---|
|
WOMAC questionnaire
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Registration Dates
First Submitted
August 21, 2010
First Submitted That Met QC Criteria
August 24, 2010
First Posted (Estimate)
August 25, 2010
Study Record Updates
Last Update Posted (Estimate)
August 25, 2010
Last Update Submitted That Met QC Criteria
August 24, 2010
Last Verified
May 1, 2005
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 13/05
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.