Right Ventricular Function in Patients With Obstructive Sleep Apnea

Right Ventricular Function in Patients With Obstructive Sleep Apnea Assessed by Real-time Three-dimensional Echocardiography

Sponsors

Lead Sponsor: Associação Fundo de Incentivo à Pesquisa

Source Associação Fundo de Incentivo à Pesquisa
Brief Summary

The purpose of this study is to determine whether patients with obstructive sleep apnea have any changes in right ventricular function evaluated by three dimensional echocardiography.

Detailed Description

Several studies have reported the association between sleep disorders to an increased risk to the development of cardiac disease. However, there is no substantial that about the influence of Obstructive Sleep Apnea on the right ventricular function. Objective: to analyse the right ventricular function in patients with Obstructive Sleep Apnea by means of Real-Time Three dimensional Echocardiography.

Overall Status Completed
Start Date June 2007
Completion Date November 2007
Study Type Observational
Enrollment 106
Condition
Eligibility

Sampling Method: Probability Sample

Criteria:

Inclusion Criteria:

- Individuals > 18 years old and < 70.

Exclusion Criteria:

- Body mass index greater than 35

- Past of clinically significant cardiac conditions

Gender: All

Minimum Age: 18 Years

Maximum Age: 70 Years

Healthy Volunteers: Accepts Healthy Volunteers

Overall Official
Last Name Role Affiliation
Orlando Campos, PhD Study Director Escola Paulista de Medicina
Location
Facility: Escola Paulista de Medicina
Location Countries

Brazil

Verification Date

June 2010

Responsible Party

Name Title: Wercules Oliveira

Organization: AFIP/Escola Paulista de Medicina

Keywords
Has Expanded Access No
Condition Browse
Arm Group

Label: Group 1 - Obstructive Sleep Apnea (OSA)

Description: Fifty-six patients with Obstructive Sleep Apnea

Label: Group 2 - Non-OSA Controls

Description: Fifty individuals without OSA with similar age, gender and body mass index (BMI)

Label: Group 3 - Treatment

Description: Fifteen patients with moderate and severe sleep apnea from group 1 underwent treatment with continuous positive airway pressure

Label: Group 4 - Placebo

Description: Fifteen patients with moderate/severe sleep apnea underwent to placebo

Study Design Info

Observational Model: Cohort

Time Perspective: Prospective

Source: ClinicalTrials.gov