- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01469741
Rehabilitation of Everyday Memory Impairment in Parkinson Disease: A Pilot Study (REMI-PD)
June 1, 2015 updated by: Erin Foster, Washington University School of Medicine
Cognitive impairment is common among non-demented individuals with Parkinson disease (PD) and is a significant source of disability and reduced quality of life.
Unfortunately, there are no successful interventions to address these impairments.
Prospective memory impairment is a particularly functionally- and clinically-relevant problem in PD.
The investigator's project will determine if a targeted intervention strategy improves PD participants' prospective memory.
The investigator's goal is to improve PD patients' everyday prospective memory so they can successfully perform desired activities and roles.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
Cognitive impairment is common among non-demented individuals with Parkinson disease (PD) and is a significant source of disability and reduced quality of life.
Unfortunately, there are no successful interventions to address these impairments.
Prospective memory impairment is a particularly functionally- and clinically-relevant problem in PD.
The investigator's project will determine if a targeted intervention strategy improves PD participants' prospective memory.
The investigator will use a randomized controlled design and a laboratory-based assessment of prospective memory to test the effect of the strategy in a controlled environment.
The investigator will also see if PD participants, with support from an occupational therapist (OT), can generalize the strategy to their complex, real-world environments and tasks.
Our goal is to improve PD patients' everyday prospective memory so they can successfully perform desired activities and roles.
Study Type
Interventional
Enrollment (Actual)
74
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Missouri
-
St. Louis, Missouri, United States, 63110
- Washington University School of Medicine
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-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
50 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- Participants will be males and females over age 50 who meet criteria for idiopathic typical PD, are Hoehn & Yahr39 stage I-III (mild-moderate disease) and are treated with levodopa/carbidopa.
Exclusion Criteria:
- Possible dementia,
- treatment with certain medications that interfere with cognition (e.g., anticholinergics),
- change in medications over the study period, other neurological disorders, brain surgery (e.g., STN DBS),
- history of psychotic disorder or significant current psychiatric disorder, or any condition that would interfere with testing (e.g., vision problems).
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Supportive Care
- Allocation: N/A
- Interventional Model: Single Group Assignment
- Masking: Single
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Investigators
- Principal Investigator: Erin Foster, OTD, OTR/L, Washington University School of Medicine, Department of Occupational Therapy
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
June 1, 2011
Primary Completion (Actual)
May 1, 2014
Study Completion (Actual)
May 1, 2014
Study Registration Dates
First Submitted
November 8, 2011
First Submitted That Met QC Criteria
November 9, 2011
First Posted (Estimate)
November 10, 2011
Study Record Updates
Last Update Posted (Estimate)
June 3, 2015
Last Update Submitted That Met QC Criteria
June 1, 2015
Last Verified
June 1, 2015
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 201103176
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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