Effect of Dental Scaling on Helicobacter Pylori Eradication and Reinfection (Scaling and Hp)

March 21, 2013 updated by: Celal Ulasoglu, Goztepe Training and Research Hospital

Patients who had received H.pylori eradication treatment will be categorised as eradication and reinfection status and whether dental scaling has any influence on these results.

Study Overview

Status

Unknown

Conditions

Helicobacter Pylori Infection

Detailed Description

Patients over 18 years with no comorbidities especially liver, cardiac and haemorrhagic diathesis and giving informed consent will be categorised according to their status of dental scaling, eradication and reinfection rates of h.pylori.

Statistical examination will include the multiple regression and Chi-Square.

The result will emphasize the influence of dental scaling on eradication (Presence of Hp cure 1-6 months after treatment) and reinfection ( reappearance of Hp 12 months later than the treatment).

Study Type

Observational

Enrollment (Anticipated)

300

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

Turkey
- - Istanbul, Turkey, 34727
    - GoztepeTRH
  - Istanbul, Turkey
    - GoztepeTRH

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 70 years (Adult, Older Adult)

Accepts Healthy Volunteers

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Eligible population with H.pylori infection and result of treatment based on presence of dental scaling.

Description

Inclusion Criteria:

Patients over 18 with h.pylori positivity and received anti-Hp treatment giving informed consent to analyse of their data on this subject.

Exclusion Criteria:

Comorbidities with cardiac, liver and medical contraindication to perform dental scaling.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Number of groups / cohorts

Cohorts and Interventions

Group / Cohort
Patients with scaling and patients without scaling No drug
Helicobacter eradicated or non-eradicated

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
The eradication and reinfection rates in dental scaled and non-scaled patients. Time Frame: last 1 year	last 1 year

Secondary Outcome Measures

Outcome Measure	Time Frame
Reinfection rate of patients treated for H.pylori Time Frame: 1 year	1 year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Goztepe Training and Research Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

March 1, 2013

Primary Completion (Anticipated)

May 1, 2013

Study Completion (Anticipated)