Acute Exacerbation of COPD and Physical Activity - Preliminary Study

People with chronic obstructive pulmonary disease (COPD) are very sedentary and efforts to establish an active lifestyle are challenging because of periodic acute exacerbations of COPD that interrupt physical activity patterns and contribute to further decline in physical activity. The purpose of this preliminary research is to learn more about the experience of acute exacerbations of COPD (AECOPD) from the perspective of the patient and his/her family and to learn how AECOPDs affect physical activity.

Study Overview

• Status: Terminated
• Conditions: Chronic Obstructive Pulmonary Disease

Detailed Description

Individuals with chronic obstructive pulmonary disease (COPD) are very sedentary and their physical activity is often interrupted by acute exacerbations of COPD (AECOPD). Little is known about the expectations had by individuals with COPD and the effects of these expectations on their physical activity. To increase the understanding of these expectations in people with COPD, a study is proposed to explore their experience of daily fluctuations in symptoms and AECOPDs, focusing on how these experiences influence health promoting behaviors, especially physical activity (PA).

This study will involve an enrollment visit during which consent will be obtained, survey data will be administered (that they may take home), spirometry testing will be conducted, and a physical activity monitor (ActivPAL device) will be applied to be worn one week to allow us to understand their usual PA. A clinical ethnographic interview will then be conducted one week following enrollment, at which point the questionnaires and ActivPAL device will be collected. A second clinical ethnographic interview will be conducted one week following the first. Survey data will again collected at week 15 by mail.

• Study Type: Observational
• Enrollment (Actual): 23

Contacts and Locations

Study Locations

• United States
  • Michigan
    • Ann Arbor, Michigan, United States, 48109
      • University of Michigan - School of Nursing

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 55 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

People with COPD, who have had an exaccerbation in the last year who live in the greater Ann Arbor area and their family members.

Description

Inclusion Criteria:

• People who have emphysema or chronic bronchitis as their primary health problem
• People who have had a respiratory infection or an exacerbation of their COPD within the last year.
• People who are 55 years or older
• Family member of someone who meets the above criteria.

Exclusion Criteria:

• Other lung diseases as their primary pulmonary problem.
• Mobility problems that limit physical activity

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort
People with COPD & recent exacerbation; The group consists of people with COPD who have had an exacerbation in the last year.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Physical activity during AECOPD	Subjects will be asked to report how they managed their physical activity during the last AECOPD. Current physical activity will be measured with accelerometry and by the CHAMPS questionnaire.	week 1

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Sense of coherence	Questionnaire that measures one's global orientation to life and the extent to which one sees life as comprehensible, manageable and meaningful.	week 1 and week 15
Barriers efficacy scale	Questionnaire that measures barriers to exercise and physical activity. The subjects reports the level of confidence they have that they can overcome each barrier.	week 1 week 15
Help seeking behavior	Questionnaire assesses help seeking with respect to healthcare services.	week 1 and week 15
COPD Stigma Scale	Questionnaire measures the stigma associated with having COPD.	week 1 and week 15

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
Social Support for Exercise	Questionnaire measures social support, positive and negative social influences for physical activity and social support for exercise.	week 1
COPD symptoms	Questionnaire, the COPD Assessment Tests quantifies severity of the most recent exacerbation.	week 1

Collaborators and Investigators

• Sponsor: University of Michigan
• Investigators: Principal Investigator: Janet L Larson, PhD, University of Michigan - School of Nursing

Study record dates

Study Major Dates

• Study Start: February 1, 2013
• Primary Completion (Actual): December 1, 2015
• Study Completion (Actual): July 1, 2021

Study Registration Dates

• First Submitted: June 3, 2013
• First Submitted That Met QC Criteria: June 3, 2013
• First Posted (Estimate): June 6, 2013

Study Record Updates

• Last Update Posted (Actual): August 10, 2021
• Last Update Submitted That Met QC Criteria: August 2, 2021
• Last Verified: August 1, 2021

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Respiratory Tract Diseases; Lung Diseases; Lung Diseases, Obstructive; Pulmonary Disease, Chronic Obstructive
• Other Study ID Numbers: HUM00062912