Computer Adaptation of Screening, Brief MET Intervention to Reduce Teen Drinking

The goal of this project is to evaluate the feasibility, acceptability, and effect size of a new computerized Motivational Enhancement Therapy (cMET) intervention for alcohol-involved adolescents in primary care.

Study Overview

• Status: Unknown
• Conditions: Tobacco Use Disorder; Substance Use; Alcohol Abuse
• Intervention / Treatment: Behavioral: cMET

Detailed Description

The study aims are to:

1. Assess cMET feasibility and acceptability and estimate its effect size on underage drinking. Hypothesis: Among 14- to 20-yr-old primary care patients, those receiving cMET will have lower rates of any alcohol use, days of alcohol use, drinks per drinking day, and days of heavy episodic drinking, than those receiving treatment as usual.
2. Estimate effect sizes for tobacco, cannabis, and other drug use, and other substance-related risks and outcomes including substance-related driving/riding, and experience of substance-related problems.
3. Identify potential moderators and mediators of cMET's effect.

• Study Type: Interventional
• Enrollment (Anticipated): 150
• Phase: Not Applicable

Contacts and Locations

Study Locations

• United States
  • Massachusetts
    • Boston, Massachusetts, United States, 02115
      • Recruiting
      • Boston Children's Hospital
      • Contact: John R Knight, MD; Phone Number: 617-355-5433; Email: john.knight@childrens.harvard.edu
      • Contact: Melissa M Weiksnar, MS, MBA; Phone Number: 857-218-4311; Email: melissa.weiksnar@childrens.harvard.edu
      • Principal Investigator: John R Knight, MD

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 14 years to 20 years (Child, Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• 14- to 20- yr-olds
• arriving for routine care to one of our participating pediatric practices (Lexington Pediatrics, Lexington, MA; East Boston Community Health Center, Longwood Pediatrics, Tufts Medical Center Adolescent Clinic, Boston, MA; Cambridge Health Alliance Dept. of Pediatrics, Cambridge, MA)
• any alcohol use days in the past 90 days,
• have an email address and internet access at home, school, or library
• provide informed assent/consent.

Exclusion Criteria:

• unable to read or understand English,
• living away at college at the time of the recruitment visit,
• not available for computer/telephone follow-ups,
• judged by the provider to be medically or emotionally unstable at the time of the visit.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
No Intervention: Treatment As Usual; Those randomized to Treatment as Usual (TAU) will not complete cMET but will receive standard treatment from the doctor.
Experimental: cMET; Those randomized to cMET will complete a 2-session computerized Motivational Enhancement Therapy (cMET) intervention.	Behavioral: cMET; Those in cMET complete the 2-session self-administered computerized intervention which includes 8 exercises designed to encourage adolescents to evaluate the impact of alcohol and other substance use on their health and well-being and consider changing their use.; Other Names: Computerized Motivational Enhancement Therapy intervention

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Alcohol use	The study investigators will measure the past 90 day alcohol use at 3-, 6-, and 9-months follow-up.	up to 9-months follow-up

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Drinks per drinking day	The study investigators will measure the number of drinks per drinking day in the past 90 days at 3-, 6-, and 9-months follow-up	up to 9-months follow-up

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
Heavy episodic drinking	The study investigators will measure the occurrences of heavy episodic drinking in the past 90 days at 3-, 6-, and 9-months follow-up.	up to 9-months follow-up

Collaborators and Investigators

• Sponsor: Boston Children's Hospital
• Investigators: Principal Investigator: John R Knight, MD, Boston Children's Hospital

Publications and helpful links

Helpful Links

• Web site of the Center for Adolescent Substance Abuse Research at Boston Children's Hospital

Study record dates

Study Major Dates

• Study Start: January 1, 2015
• Primary Completion (Anticipated): August 1, 2017
• Study Completion (Anticipated): August 1, 2017

Study Registration Dates

• First Submitted: June 18, 2013
• First Submitted That Met QC Criteria: June 19, 2013
• First Posted (Estimate): June 20, 2013

Study Record Updates

• Last Update Posted (Actual): April 20, 2017
• Last Update Submitted That Met QC Criteria: April 18, 2017
• Last Verified: April 1, 2017

More Information

Terms related to this study

• Keywords: Adolescents; Alcohol abuse; Motivational Enhancement Therapy; Tobacco use disorder; Substance use
• Additional Relevant MeSH Terms: Mental Disorders; Chemically-Induced Disorders; Drinking Behavior; Alcohol-Related Disorders; Alcohol Drinking; Substance-Related Disorders; Alcoholism; Tobacco Use Disorder; Underage Drinking
• Other Study ID Numbers: JRKnightR34PA-13-078

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO