TIVA, Inhalation Anesthesia, and Surgical Site Infection

July 9, 2015 updated by: Hyo-Seok Na, Seoul National University Bundang Hospital
The purpose of this retrospective study was to evaluate the incidence of SSI after colorectal surgery under the general anesthesia by different general anesthetic technique: inhalation versus total intravenous anesthesia.

Study Overview

Status

Completed

Conditions

Study Type

Observational

Enrollment (Actual)

2046

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Korea, Republic of
    • Gyeonggi-do
      • Seongnam-si, Gyeonggi-do, Korea, Republic of, 463-707
        • Seoul National University Bundang Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

20 years to 90 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Adult patients who underwent elective colorectal surgery under general anesthesia from January 2011 to December 2013 at SNUBH.

Description

Inclusion Criteria:

  • Adult patients who underwent elective colorectal surgery under general anesthesia from January 2011 to December 2013.

Exclusion Criteria:

  • None

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Case-Control
  • Time Perspectives: Retrospective

Cohorts and Interventions

Group / Cohort
Total intravenous anesthesia
Total intravenous anesthesia using propofol and remifentanil
Inhalation
Balanced inhalation anesthesia using volatile anesthetics and remifentanil

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Surgical site infection
Time Frame: Postoperative 30 day
Number of participants with surgical site infection
Postoperative 30 day

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Postoperative C-reactive protein
Time Frame: Postoperative 1 day
Plasma concentration
Postoperative 1 day
Segmented neutrophil count
Time Frame: Preoperaitve 1 day, postoperative 1 day
Segmented neutrophil count
Preoperaitve 1 day, postoperative 1 day
Transfusion
Time Frame: The day of operation, postoperative 30 day
Number of unit of transfused red blood cells
The day of operation, postoperative 30 day

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Seoul National University Bundang Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

January 1, 2015

Primary Completion (Actual)

June 1, 2015

Study Completion (Actual)

June 1, 2015

Study Registration Dates

First Submitted

June 17, 2015

First Submitted That Met QC Criteria

July 7, 2015

First Posted (Estimate)

July 10, 2015

Study Record Updates

Last Update Posted (Estimate)

July 13, 2015

Last Update Submitted That Met QC Criteria

July 9, 2015

Last Verified

July 1, 2015

More Information

Terms related to this study

Other Study ID Numbers

  • SSI_anesthesia

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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