Cerebral Bases of Arithmetics Processing

December 13, 2025 updated by: Hospices Civils de Lyon

Neural Bases of Arithmetic Processing: MRIf Study in Adults and Children

The aim of this study was to identify neural correlates involved in arthmetics processing in adults and children aged 8 to 14 with normal cognitive function. Brain area will be identified by functional magnetic resonance imaging (IRMf).

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

79

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • France
      • Bron, France, 69677
        • Médecine nucléaire, Groupement Hospitalier Est, HCL

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

8 years to 24 years (Child, Adult)

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • children aged 8 to 14 with parents' consent
  • adults aged 18 to 24
  • right-handed
  • affiliated to the French social security

Exclusion Criteria:

  • known neurological disorders including epilepsia
  • known psychiatric disorders including Attention Deficit Disorder
  • birth complications needing intensive care
  • central nervous system treatment
  • important hearing disabilities
  • not corrected impaired vision

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Other
  • Allocation: Non-Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Healthy subjects aged 18 to 24
Subjects without neurological or psychiatric history
Other: functional magnetic resonance imaging
Other Names:
  • IRMf
Other: neuropsychological testing
Other: simple arithmetic operations
Experimental: Healthy subjects aged 8 to 11
Subjects without neurological or psychiatric history
Other: functional magnetic resonance imaging
Other Names:
  • IRMf
Other: neuropsychological testing
Other: simple arithmetic operations
Experimental: Healthy subjects aged 12 to 14
Subjects without neurological or psychiatric history
Other: functional magnetic resonance imaging
Other Names:
  • IRMf
Other: neuropsychological testing
Other: simple arithmetic operations

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Brain area activity in arithmetic processing will be identified by IRMf
Time Frame: up to 60 days after inclusion
Brain activity is identified by IRMf
up to 60 days after inclusion

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Parietal region activity in arithmetic processing will be identified by IRMf
Time Frame: up to 60 days after inclusion
comparison between group aged to 12to 14 and group aged to 8 to 11
up to 60 days after inclusion

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Hospices Civils de Lyon

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

March 18, 2014

Primary Completion (Actual)

May 9, 2018

Study Completion (Actual)

May 9, 2018

Study Registration Dates

First Submitted

September 2, 2016

First Submitted That Met QC Criteria

September 8, 2016

First Posted (Estimated)

September 14, 2016

Study Record Updates

Last Update Posted (Estimated)

December 19, 2025

Last Update Submitted That Met QC Criteria

December 13, 2025

Last Verified

December 1, 2025

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2013.801

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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