Examining Measurement of Behavioral Neglect Post Stroke

The purpose of this study is to examine measurement of unilateral neglect post stroke. Although a number of clinical assessments are used to measure neglect, it is unclear whether items from some of the most commonly used assessments are able to effectively and comprehensively measure neglect. This study will determine whether these assessments measure different aspects of neglect and whether items from various neglect assessments can be combined to more effectively measure neglect.

Study Overview

• Status: Completed
• Conditions: Stroke; Hemispatial Neglect

Detailed Description

Many individuals have difficulty attending to the affected side of their body or to the affected side of space after stroke (unilateral neglect). Although a number of clinical assessments are used to measure this inattention, it is unclear whether items from some of the most commonly used assessments are able to effectively and comprehensively measure inattention. Clinical assessments provide critical information to clinicians and researchers and are used to inform treatment and document patient progress. Therefore, it is important that investigators more closely examine these existing assessments.

Individuals who demonstrate impaired attention to the affected side after stroke also have greater motor impairment than individuals who do not have impaired attention, but investigators do not know how inattention affects reaching movements using the impaired arm. This study will examine various methods used to assess inattention to the affected side after stroke and also examine how inattention affects reaching movements of the impaired arm.

• Study Type: Observational
• Enrollment (Actual): 55

Contacts and Locations

Study Locations

• United States
  • South Carolina
    • Charleston, South Carolina, United States, 29425
      • Medical University of South Carolina

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Stroke survivors

Description

Inclusion Criteria:

• Unilateral hemispheric stroke
• 18 years or older

Exclusion Criteria:

• Severe aphasia
• Inability to follow 2-step directions
• Presence of other neurological disease that may impair vision or perception during performance of evaluation procedures

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort
Stroke Survivors; Individuals who have experienced a unilateral hemispheric stroke

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Catherine Bergego Scale	One-time assessment scheduled over 1-2 days
Behavioral Inattention Test	One-time assessment scheduled over 1-2 days
Naturalistic Action Test	One-time assessment scheduled over 1-2 days
Virtual Reality Lateralized Attention Test	One-time assessment scheduled over 1-2 days
Kinematic Assessment of Arm Movement	One-time assessment scheduled over 1-2 days

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Arm Use measured by Accelerometers	Accelerometers will be issued on the first assessment day. Participants will wear accelerometers for 3 days.	One-time assessment scheduled over 3 days

Collaborators and Investigators

• Sponsor: Medical University of South Carolina
• Investigators: Principal Investigator: Michelle Woodbury, PhD, OTR/L, Medical University of South Carolina

Publications and helpful links

General Publications

• Grattan ES, Woodbury ML. Do Neglect Assessments Detect Neglect Differently? Am J Occup Ther. 2017 May/Jun;71(3):7103190050p1-7103190050p9. doi: 10.5014/ajot.2017.025015.

Study record dates

Study Major Dates

• Study Start: January 1, 2016
• Primary Completion (Actual): February 21, 2020
• Study Completion (Actual): February 21, 2020

Study Registration Dates

• First Submitted: October 12, 2016
• First Submitted That Met QC Criteria: October 13, 2016
• First Posted (Estimate): October 17, 2016

Study Record Updates

• Last Update Posted (Actual): November 25, 2022
• Last Update Submitted That Met QC Criteria: November 22, 2022
• Last Verified: November 1, 2022

More Information

Terms related to this study

• Keywords: Rehabilitation; Stroke; Neglect
• Additional Relevant MeSH Terms: Cardiovascular Diseases; Vascular Diseases; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurologic Manifestations; Neurobehavioral Manifestations; Stroke; Perceptual Disorders
• Other Study ID Numbers: PR00044531

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO