Does the Ingestion of Mycoprotein Elicit an Optimal Anabolic Response in Resting and Exercised Skeletal Muscle? (ARM)

April 25, 2025 updated by: University of Exeter
The present study will seek to quantify the muscle protein synthetic response to mycoprotein feeding, comparing it to milk protein as a gold standard and heavily researched positive control

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

20

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United Kingdom
    • Devon
      • Exeter, Devon, United Kingdom, EX1 2LU
        • University of Exeter, Sports & Health Sciences, College of Life & Environmental Sciences

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 40 years (Adult)

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

• BMI between 18 and 30 -

Exclusion Criteria:

  • Any diagnosed metabolic impairment (e.g. type 1 or 2 Diabetes)
  • Any diagnosed cardiovascular disease or hypertension.
  • Elevated blood pressure at the time of screening (e.g. blood pressure of ≥140/90mmHg).
  • Chronic use of any prescribed or over the counter pharmaceuticals.
  • A personal or family history of epilepsy, seizures or schizophrenia.
  • Anyone with previous motor disorders.
  • An allergy to mycoprotein / Quorn, penicillin, or milk.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Basic Science
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: Mycoprotein beverage
Other: Mycoprotein beverage
Mycoprotein protein beverage
Placebo Comparator: Milk protein beverage
Other: Milk protein beverage
Milk protein beverage

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Muscle fractional synthetic rate (muscle protein synthesis)
Time Frame: 7.5 hours
7.5 hours

Secondary Outcome Measures

Outcome Measure
Time Frame
Plasma amino acid concentration
Time Frame: 7.5 hours
7.5 hours
Serum insulin concentration
Time Frame: 7.5 hours
7.5 hours
Molecular markers of muscle anabolism
Time Frame: 7.5 hours
7.5 hours

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Exeter

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 26, 2017

Primary Completion (Actual)

May 1, 2018

Study Completion (Actual)

May 1, 2022

Study Registration Dates

First Submitted

December 2, 2016

First Submitted That Met QC Criteria

December 2, 2016

First Posted (Estimated)

December 6, 2016

Study Record Updates

Last Update Posted (Actual)

April 30, 2025

Last Update Submitted That Met QC Criteria

April 25, 2025

Last Verified

April 1, 2025

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 660065600

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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