Prone Position Impact in ARDS Patients on the Incidence of Central Venous Catheter Colonization (ILCDV)

Prone Position Impact in Patients With Acute Respiratory Distress Syndrome on the Incidence of Central Venous Catheter Colonizations in Reanimation

Catheter colonization, catheter-associated infection and catheter-associated bacteremia are a major challenge for resuscitation unit. This study wishes to explore the impact of the central venous catheter colonization on the ARDS patient with and without prone position.

Study Overview

• Status: Completed
• Conditions: Catheter Infection; ARDS, Human

Detailed Description

Catheter-associated infection prevention is achieved by identification of the population at risk. Patients receiving prone position Under acute respiratory distress syndrome appear to be particularly vulnerable. This retrospective study is designed to compare the risk of catheter colonization that could be induced or worsened by prone position. Knowing that, prone position is increased into the care acute respiratory distress syndrome since few years. Unfortunately, no study has examined the prone position impact on catheter-association infection in these population.

• Study Type: Observational
• Enrollment (Actual): 202

Contacts and Locations

Study Locations

• France
  • Metz, France, 57085
    • CHR Metz Thionville

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

ARDS patients with a central venous catheter placed or not into prone position

Description

Inclusion Criteria:

• Hospitalized patient in the reanimation unit of the CHR Metz-Thionville or the CHRU Nancy between january 2014 and december 2015
• Patient with an acute respiratory distress syndrome, moderate or severe
• With a central venous catheter
• With or without prone position during the stay

Exclusion Criteria:

• Minor patient
• Absence of information on central venous catheter bacteriology

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Impact of the prone position	Incidence rate of the bacterial colonization at least one catheter during the stay in resuscitation unit	Day 1

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Infection associated factors	multivariate analysis of risks factor for the catheter colonization ((age, sex, comorbidity, weight, length of stay)	Day 1

Collaborators and Investigators

• Sponsor: Centre Hospitalier Régional Metz-Thionville

Study record dates

Study Major Dates

• Study Start (Actual): November 2, 2017
• Primary Completion (Actual): June 4, 2018
• Study Completion (Actual): January 1, 2019

Study Registration Dates

• First Submitted: January 12, 2018
• First Submitted That Met QC Criteria: January 12, 2018
• First Posted (Actual): January 19, 2018

Study Record Updates

• Last Update Posted (Actual): February 4, 2019
• Last Update Submitted That Met QC Criteria: February 1, 2019
• Last Verified: January 1, 2018

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Respiratory Tract Diseases; Respiration Disorders; Lung Diseases; Respiratory Distress Syndrome
• Other Study ID Numbers: 2017-02-CHRMT

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No