Does Hemodialysis Affect Upper Extremity Functional Capacity, Physical Activity and Physical Function of Patients?

Atılım University, Physiotherapy and Rehabilitation Department

This study was planned to determine the effects of upper extremity functional capacity, physical activity level and physical functions of patients receiving hemodialysis treatment.

Study Overview

• Status: Completed
• Conditions: Chronic Kidney Diseases
• Intervention / Treatment: Diagnostic test: Hand grip, joint range of motion , functional level of the upper extremity, physical activity levels

Detailed Description

Upper extremity functional capacity, physical activity level and physical functions were evaluated in healthy subjects and hemodialysis patients.

• Study Type: Interventional
• Enrollment (Actual): 100
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Turkey
  • Ankara
    • Gölbaşı, Ankara, Turkey, 06830
      • Atılım University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 70 years (Adult, Older Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

Description

Inclusion criteria:

In study group,

• with cooperation
• hemodialysis treatment for at least 3 months
• with single-sided fistula

In the control group,

• healthy volunteers with no history of trauma or surgery in the upper extremity,
• with cooperating

Exclusion Criteria:

• Individuals with orthopedic problems associated with chronic renal failure,
• Upper limb functions affected

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Screening
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: dialysis patients; Dialysis patients were evaluated by objective diagnostic tests.	Diagnostic test: Hand grip, joint range of motion , functional level of the upper extremity, physical activity levels; Hand grip force with Jamar Hand Dynamometer, joint range of motion with Baseline Digital Goniometer, functional level of the upper extremity with the Shoulder-Arm and Hand Problems Questionnaire(DASH), physical activity levels with International Physical Activity Questionnaire Short Form(IPAQ-short form) and physical functions with Human Activity Profile (HAP) were evaluated.
Experimental: Control group; Healthy individuals	Diagnostic test: Hand grip, joint range of motion , functional level of the upper extremity, physical activity levels; Hand grip force with Jamar Hand Dynamometer, joint range of motion with Baseline Digital Goniometer, functional level of the upper extremity with the Shoulder-Arm and Hand Problems Questionnaire(DASH), physical activity levels with International Physical Activity Questionnaire Short Form(IPAQ-short form) and physical functions with Human Activity Profile (HAP) were evaluated.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Evaluation of The Upper Extremity Functional Level	Turkish version of the Shoulder, Arm and Hand Problems Questionnaire (The DASH-T) was used to asses the functional level of the upper extremity. Turkish version of the shoulder, arm and hand problems questionnaire consists of 30 questions. The first 20 questions are to examine physical competence, and the last 10 questions question pain and related functional and environmental constraints. As the score is closer to zero, the functional level of the person is high; as the score is far from zero the functional level of the person is low .	Evaluations were made after hemodialysis patients rested for half an hour after treatment.

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Evaluation of Physical Activity Level	To asses the level of physical activity, The Turkish version of International Physical Activity Questionnaire Short Form was used . In the turkish version of international physical activity questionnaire short form, physical activities were made at least 10 minutes at a time. In the last 7 days of the survey; Severe physical activity duration (min), moderate physical activity duration (min), walking and one day sitting time (min) were questioned. According to the total physical activity score, the physical activity levels of the participants were classified as low level (under 600 MET min /week), intermediate level (600-3000 MET-min /week) and high level (over 3000 MET-min / week) .	Evaluations were made after hemodialysis patients rested for half an hour after treatment.
Evaluation of Physical Function Level	The Human Activity Profile (HAP) was used to measure the physical function level. Human activity profile is a scale consisting of 94 items developed to determine the level of physical function in healthy individuals or individuals with chronic diseases at different ages . For each of the 94 items the respondent is asked to indicate whether they are still doing the activity, stopped doing the activity or have never done the activity before. Two scores are calculated: the maximum activity score (MAS) and the adjusted activity score (AAS). The physical activity level of the person is in one of 3 subgroups according to the adjusted activity score: <53 points: insufficient activity level, 53-74 points: moderately active and > 74 points: active .	Evaluations were made after hemodialysis patients rested for half an hour after treatment.

Collaborators and Investigators

• Sponsor: NAİME ULUG
• Investigators: Principal Investigator: Fatma Cansu AKTAŞ, MsC, Atılım University

Study record dates

Study Major Dates

• Study Start (Actual): April 1, 2018
• Primary Completion (Actual): January 1, 2019
• Study Completion (Actual): June 30, 2019

Study Registration Dates

• First Submitted: September 19, 2019
• First Submitted That Met QC Criteria: September 20, 2019
• First Posted (Actual): September 23, 2019

Study Record Updates

• Last Update Posted (Actual): September 23, 2019
• Last Update Submitted That Met QC Criteria: September 20, 2019
• Last Verified: September 1, 2019

More Information

Terms related to this study

• Keywords: physical activity; physical function; Hemodialysis; upper extremity; chronic renal failure
• Additional Relevant MeSH Terms: Urologic Diseases; Renal Insufficiency; Kidney Diseases; Renal Insufficiency, Chronic
• Other Study ID Numbers: 23/23

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No