the Antibacterial Effect of Zinc ,Silver and Fluoride

March 30, 2020 updated by: Dina mounir elkady, Cairo University

the Antibacterial Effect of Different Glass Ionomer Restoration Containing Zinc ,Silver and Fluoride Ion:in Situ Study

natural teeth will be filled with the 3 different material then the dentin sample will be collected ,bacterial culture and elementary analysis will be done

Study Overview

Status

Unknown

Conditions

Intervention / Treatment

Detailed Description

orthodontic patient with premolar indicated for extraction , teeth will restored with the different material 3 months before doing extraction

Study Type

Interventional

Enrollment (Anticipated)

50

Phase

  • Not Applicable

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

10 years to 30 years (Child, Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • patient need teeth extraction for orthodontic treatment

Exclusion Criteria:

  • carious teeth deciduous teeth

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Triple

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: conventional glass ionomer
Procedure: conventional glass ionomer
occlusal cavity filled with conventional glass ionomer
Experimental: zinc modified glass ionomer
Procedure: zinc modified
occlusal cavity filled with zinc modified
Experimental: silver modified glass ionomer
Procedure: silver modified glass ionomer
occlusal cavity filled with silver modified

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
bacterial count
Time Frame: 3months
streptococcus mutant count by culture of dentin sample excavated from the tooth after restoration removal
3months
elementary analysis of dentin
Time Frame: 3months
elementary analysis of dentin component excavated from the cavity after restoration removal to detect the change in tooth mineral
3months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Cairo University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Anticipated)

July 15, 2021

Primary Completion (Anticipated)

July 15, 2021

Study Completion (Anticipated)

July 15, 2021

Study Registration Dates

First Submitted

July 17, 2018

First Submitted That Met QC Criteria

March 30, 2020

First Posted (Actual)

April 1, 2020

Study Record Updates

Last Update Posted (Actual)

April 1, 2020

Last Update Submitted That Met QC Criteria

March 30, 2020

Last Verified

March 1, 2020

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 6679

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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