The Danish Occupational Medicine Cohort - Long-term Prognosis for Patients With Work-related Disorders (PRORISK)

Each year about 10.000 patients are referred due to suspected work-related disorders to the Danish departments of occupational medicine. In Denmark and internationally there is a lack of follow-up studies investigating the long-term prognosis of employees with work-related disorders. To facilitate long-term prognostic studies for work-related conditions a Danish Occupational Medicine Cohort has been established through the Danish population registers.

Study Overview

• Status: Active, not recruiting
• Conditions: Work-Related Condition

Detailed Description

Danish departments of occupational medicine examine around 10,000 patients each year referred due to suspected work-related disorders. In Denmark and internationally there is a lack of follow-up studies investigating the long-term prognosis of employees with work-related disorders. The purpose of this cohort is to facilitate long-term prognostic studies for conditions such as mental or musculoskeletal disorders.

The Danish Occupational Medicine cohort has been created through The Danish National Patient Register and comprises all patients seen in Danish Departments of Occupational Medicine from 2000-2018 (N=145.521). Numerous register data are included in the database from five years prior to time of inclusion until 2018. Examples of register data are; information on work, sickness absence and disability as well as number and type of contacts to health services, use of medication, income, education, type of occupation, social status, death and cause of death. Job Exposure Matrices (JEMs) on physical and psychosocial work exposure, life styles and other matrices are also available. The cohort will be updated with new patients and register data regularly.

• Study Type: Observational
• Enrollment (Actual): 145521

Contacts and Locations

Study Locations

• Denmark
  • Central Denmark Region
    • Herning, Central Denmark Region, Denmark, 7400
      • David H Christiansen

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 16 years and older (Child, Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

The cohort was created through The Danish National Patient Register and comprises all patients seen in Danish Departments of Occupational Medicine from 2000-2018 (N= 145.521). Numerous register data are included in the database from five years prior to time of inclusion until 2018. The cohort will be updated with new patients and register data regularly.

Description

Inclusion Criteria:

• A record of contact at Danish departments of occupational medicine with a relevant primary or secondary diagnosis according to the International Classification of Diseases, 10th revision.

Exclusion Criteria:

• No record of contact or only a record of referral without subsequent records of relevant primary or secondary diagnosis.

Study Plan

How is the study designed?

Design Details

• Observational Models: Cohort
• Time Perspectives: Prospective

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Annual work participation score	Work participation score is defined as number of weeks of employment relative to the total sum of number of weeks of employment plus number of weeks on temporary or permanent health related public compensation as registered by the Danish National Register on Public Transfer Payments register (DREAM).	5 years
Annual health care utilization	Primary and secondary Health care contacts - includes all face to face contacts from the Danish National Health Service Register and Danish National Patient Register	5 years

Collaborators and Investigators

• Sponsor: Regional Hospital West Jutland
• Collaborators: Aarhus University Hospital Skejby; University of Aarhus; Aalborg University Hospital
• Investigators: Principal Investigator: David H Christiansen, Occupational Medicine, Regional Hospital Herning

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2000
• Primary Completion (Anticipated): December 31, 2025
• Study Completion (Anticipated): December 31, 2025

Study Registration Dates

• First Submitted: July 1, 2020
• First Submitted That Met QC Criteria: July 1, 2020
• First Posted (Actual): July 7, 2020

Study Record Updates

• Last Update Posted (Actual): September 16, 2021
• Last Update Submitted That Met QC Criteria: September 14, 2021
• Last Verified: September 1, 2021

More Information

Terms related to this study

• Keywords: Prognosis; Work-related disorders; Occupational medicine
• Other Study ID Numbers: DST7055

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No