Vaccination Practices for Inflammatory Bowel Disease Patients in China With Gastroenterologists

Insufficient Awareness and Vaccination Practices for Inflammatory Bowel Disease Patients in China: A Multi-center Survey of Chinese Gastroenterologists

The aim of the current study was to evaluate the knowledge of Chinese gastroenterologists on vaccinating patients with IBD under the assistance of Chinese Crohn's & Colitis Foundation. The Chinese Crohn's & Colitis Foundation (CCCF) is the first nonprofit,volunteer-driven foundation specifically for patients with IBD in China.It has been joined by IBD specialists at various hospitals in China.

Study Overview

• Status: Completed
• Conditions: Inflammatory Bowel Diseases

Detailed Description

The questionnaire contained questions regarding the respondents'information, including their gender, years in practice, clinical specialty,and source of knowledge on immunization practices. The questionnaire mainly contained three sections: knowledge of vaccinations for hepatitis A virus (HAV), HBV, and varicella; current vaccination practices for the IBD group; and reasons for not recommending these vaccinations to patients with IBD. The questionnaire composed of 13 items specifically on the three vaccinations mentioned above for immunosuppressed patients with IBD. All questions were conducted based on recognized guidelines and were reviewed by 18 IBD experts. The questionnaire captured the frequency with which the respondents assessed patients with IBD for anti-HAV/hepatitis B surface antigen (HBsAg), hepatitis B core antibody, and hepatitis B surface antibody/ anti-HAV levels, and acquired infection and immunization histories. Whether the respondents recommended these three vaccines to the IBD group before treatment was also elicited.

• Study Type: Observational
• Enrollment (Actual): 307

Contacts and Locations

Study Locations

• China
  • Hangzhou
    • Zhejiang, Hangzhou, China, 310009
      • Shuyan Li

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: ADULT; OLDER_ADULT; CHILD
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

An email with a quick response code (QRC) was sent to CCCF-affiliated gastroenterologists specializing in IBD between July 2017 and August 2017

Description

Inclusion Criteria:

• gastroenterologists were members of tertiary hospitals

Exclusion Criteria:

• pediatricians were excluded, as were retired gastroenterologists and those currently in training

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
vaccination practices	The questionnaire mainly contained three sections: knowledge of vaccinations for hepatitis A virus (HAV), HBV, and varicella; current vaccination practices for the IBD group; and reasons for not recommending these vaccinations to patients with IBD. The questionnaire captured the frequency with which the respondents assessed patients with IBD for anti-HAV/hepatitis B surface antigen (HBsAg), hepatitis B core antibody, and hepatitis B surface antibody/ anti-HAV levels, and acquired infection and immunization histories.	between July 2017 and August 2017

Collaborators and Investigators

• Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University
• Collaborators: Peking Union Medical College Hospital; Zhujiang Hospital; Sixth Affiliated Hospital, Sun Yat-sen University; The First Affiliated Hospital of Zhejiang Chinese Medical University; Nanjing University of Chinese Medicine; The Ruijin Hospital, Shanghai Jiao Tong University School of Medicine; The Xinqiao Hospital, Army Medical University; Lishui Municipal Central Hospital, the Fifth Affiliated Hospital of Wenzhou Medical University; Shaoxing Shangyu People's Hospital

Study record dates

Study Major Dates

• Study Start (ACTUAL): July 1, 2017
• Primary Completion (ACTUAL): July 1, 2017
• Study Completion (ACTUAL): August 1, 2017

Study Registration Dates

• First Submitted: June 17, 2021
• First Submitted That Met QC Criteria: July 1, 2021
• First Posted (ACTUAL): July 2, 2021

Study Record Updates

• Last Update Posted (ACTUAL): July 19, 2021
• Last Update Submitted That Met QC Criteria: July 13, 2021
• Last Verified: July 1, 2021

More Information

Terms related to this study

• Keywords: inflammatory bowel diseases， vaccination
• Additional Relevant MeSH Terms: Digestive System Diseases; Gastrointestinal Diseases; Gastroenteritis; Inflammatory Bowel Diseases; Intestinal Diseases
• Other Study ID Numbers: 2020-089

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No