Impaired Toilet Training, LUTS and Bowel Dysfunction in Children With DCD

Impaired Toilet Training, Lower Urinary Tract Symptoms and Bowel Dysfunction in Children With Developmental Coordination Disorder

This cross-sectional case-control study aimed to determine whether there is a significant difference in the prevalence of impaired toilet training, LUTS, and functional bowel problems among children diagnosed with DCD and typically developing children (TDC).

Study Overview

• Status: Recruiting
• Conditions: Lower Urinary Tract Symptoms; Developmental Coordination Disorder; Bowel Dysfunction
• Intervention / Treatment: Other: Vancouver symptom score for dysfunctional elimination symptoms Questionnaire; Other: Developmental Coordination Disorder Questionnaire; Other: Questionnaire concerning impaired toilettraining and comorbities

• Study Type: Observational
• Enrollment (Estimated): 84

Contacts and Locations

• Study Contact: Name: Bieke Samijn, PhD; Phone Number: +32 9 332 19 38; Email: bieke.samijn@ugent.be

Study Locations

• Belgium
  • Ghent, Belgium
    • Recruiting
    • University Hospital Ghent
    • Contact: Bieke Samijn; Phone Number: +32 9 332 19 38; Email: bieke.samijn@uzgent.be
  • East Flanders
    • Ghent, East Flanders, Belgium, 9000
      • Recruiting
      • Ghent University Hospital/Ghent University
      • Contact: Bieke Samijn, Dr.; Phone Number: +32 9 332 19 38; Email: Bieke.Samijn@UGent.be

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child
• Accepts Healthy Volunteers: Yes

• Sampling Method: Non-Probability Sample

Study Population

Children with developmental coordination disorder and grade- and gender matched typically developing children.

Description

Inclusion Criteria:

• Diagnosed with DCD by a multidisciplinary team (DCD case group)
• Children with a typical development, grade and gender matched with the DCD case group (TDC control group).

Exclusion Criteria:

• A DCD-Q score indicative for DCD (TDC control group)
• Presence of other developmental disorders, such as ASS, ADHD or intellectual disability (TDC control group)

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
DCD case group; The case group consists of children with developmental coordination disorder.	Other: Vancouver symptom score for dysfunctional elimination symptoms Questionnaire; Vancouver symptom score for dysfunctional elimination syndrome, Dutch version, validated by 't Hoen et al. 2016. The questionnaire is filled in by the parents of the child.; Other Names: VSSDES; Other: Developmental Coordination Disorder Questionnaire; Validated Developmental Coordination Disorder Questionnaire, Dutch version includes assessment of motor functioning. The questionnaire is filled in by the parents of the child.; Other Names: DCD-Q; CVO; Other: Questionnaire concerning impaired toilettraining and comorbities; Unvalidated, complementary questions concerning impaired toilettraining and comorbidities. Questions were based on ICCS standardisation guidelines (Austin et al., 2015). The questionnaire is filled in by the parents of the child.
TDC control group; The control group consists of typically developing children, grade and gender matched with the DCD case group.	Other: Vancouver symptom score for dysfunctional elimination symptoms Questionnaire; Vancouver symptom score for dysfunctional elimination syndrome, Dutch version, validated by 't Hoen et al. 2016. The questionnaire is filled in by the parents of the child.; Other Names: VSSDES; Other: Developmental Coordination Disorder Questionnaire; Validated Developmental Coordination Disorder Questionnaire, Dutch version includes assessment of motor functioning. The questionnaire is filled in by the parents of the child.; Other Names: DCD-Q; CVO; Other: Questionnaire concerning impaired toilettraining and comorbities; Unvalidated, complementary questions concerning impaired toilettraining and comorbidities. Questions were based on ICCS standardisation guidelines (Austin et al., 2015). The questionnaire is filled in by the parents of the child.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Impaired toilet training	Prevalence of impaired toilet training in children with DCD compared to TDC	through study completion, 25 minutes
Daytime incontinence	Prevalence of daytime incontinence at 5 years old in children with DCD compared to TDC	through study completion, 25 minutes
Enuresis	Prevalence of enuresis at 5 years old in children with DCD compared to TDC	through study completion, 25 minutes
Fecal incontinence	Prevalence of fecal incontinence at 4 years old in children with DCD compared to TDC	through study completion, 25 minutes

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Toilet training difficulties	Prevalence and amount of toilet training difficulties in children with DCD compared to TDC	through study completion, 25 minutes
General bladder and bowel dysfunction	Prevalence of LUTS, bowel problems or combined bladder and bowel dysfunction in children with DCD compared to TDC	through study completion, 25 minutes

Collaborators and Investigators

• Sponsor: University Hospital, Ghent
• Investigators: Principal Investigator: Ellen Vandamme, MD, University Hospital, Ghent; Principal Investigator: Bieke Samijn, PhD, University Ghent

Study record dates

Study Major Dates

• Study Start (Actual): March 14, 2023
• Primary Completion (Estimated): June 1, 2025
• Study Completion (Estimated): June 1, 2025

Study Registration Dates

• First Submitted: March 7, 2024
• First Submitted That Met QC Criteria: March 7, 2024
• First Posted (Actual): March 15, 2024

Study Record Updates

• Last Update Posted (Actual): August 2, 2024
• Last Update Submitted That Met QC Criteria: August 1, 2024
• Last Verified: August 1, 2024

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Mental Disorders; Digestive System Diseases; Urological Manifestations; Neurodevelopmental Disorders; Lower Urinary Tract Symptoms; Gastrointestinal Diseases; Intestinal Diseases; Motor Skills Disorders
• Other Study ID Numbers: #BC-11326 AM04

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No