Renalase(rs10887800) Genotyping & Leucocytes Telomere Length in Postpartum. Hypertension

July 12, 2024 updated by: Amera Morad Foad, Sohag University

Renalase(rs10887800) Genotyping & Leucocytes Telomere Length in Patients With Postpartum Hypertension.

This is an observertional study aimed at Study the association between Renalase(rs10887800) Genotyping & Leucocytes telomere length in patients with postpartum hypertension whether new onset( denovo) or persistent following pregnancy complicated by hypertension.

Study Overview

Study Type

Observational

Enrollment (Estimated)

90

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

      • Sohag, Egypt
        • Recruiting
        • Sohag university hosoital
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

N/A

Sampling Method

Probability Sample

Study Population

Patients who were 18 years or above, and have a diagnosis of postpartum hypertension

Description

Inclusion Criteria:

  • Patients who are18 years or above, and have a diagnosis of postpartum hypertension(regardless of where they received their antenatal care) attended to Sohag university hospitals

Exclusion Criteria:

  • All pregnant women with medical disorders in pregnancy other than Hypertensive disorders during pregnancy (e.g., sickle cell disease, heart disease, kidney and other connective tissues disorders) will be excluded from the study. Also we excluded measurements taken during scheduled or unscheduled surgical encounters given potential for interaction with anesthetic agents

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
denovo postpartum hypertension
females with new onset hypertension after delivary
persitant postpartum hypertension
females with preexisting hypertension or preeclampsia that persist after delivery
control
females with normal postpartum blood pressure

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Renalase(rs10887800) Genotyping
Time Frame: 1 year
The presence of gene polymorphism whether homogenetic or heterogenetic
1 year

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Leucocytes telomere length
Time Frame: 1 year
Measurement of the relative length of WBCs telomere in patints with postpartum hypertension
1 year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Investigators

  • Principal Investigator: Amera Morad Foad, assistant professor, Sohag University Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

June 25, 2024

Primary Completion (Estimated)

June 25, 2025

Study Completion (Estimated)

September 1, 2025

Study Registration Dates

First Submitted

July 8, 2024

First Submitted That Met QC Criteria

July 8, 2024

First Posted (Actual)

July 15, 2024

Study Record Updates

Last Update Posted (Actual)

July 16, 2024

Last Update Submitted That Met QC Criteria

July 12, 2024

Last Verified

July 1, 2024

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • Soh-Med-24-06-08PD

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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